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  1. Book: Exoscope-Assisted Surgery in Otorhinolaryngology

    de Virgilio, Armando / Spriano, Giuseppe

    2021  

    Language English
    Size 154 p.
    Publisher Elsevier Science
    Document type Book
    Note PDA Manuell_11
    Format 192 x 233 x 10
    ISBN 9780323831680 ; 0323831680
    Database PDA

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  2. Article ; Online: Is the robot an instrument or an indication for transoral surgery?

    De Virgilio, Armando / Virós Porcuna, David / Sampieri, Claudio / Costantino, Andrea

    Oral oncology

    2024  Volume 153, Page(s) 106716

    MeSH term(s) Humans ; Robotic Surgical Procedures/instrumentation ; Robotic Surgical Procedures/methods ; Robotics/instrumentation ; Robotics/methods
    Language English
    Publishing date 2024-02-19
    Publishing country England
    Document type Letter ; Editorial
    ZDB-ID 1120465-5
    ISSN 1879-0593 ; 0964-1955 ; 1368-8375
    ISSN (online) 1879-0593
    ISSN 0964-1955 ; 1368-8375
    DOI 10.1016/j.oraloncology.2024.106716
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  3. Article ; Online: Microvascular anastomosis in head and neck free flap reconstruction using the RoboticScope.

    De Virgilio, Armando / Pace, Gian Marco / Costantino, Andrea / Russo, Elena / Festa, Bianca Maria

    American journal of otolaryngology

    2024  Volume 45, Issue 4, Page(s) 104363

    Language English
    Publishing date 2024-04-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 604541-8
    ISSN 1532-818X ; 0196-0709
    ISSN (online) 1532-818X
    ISSN 0196-0709
    DOI 10.1016/j.amjoto.2024.104363
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  4. Article ; Online: Theranostics of Thyroid Cancer.

    Giovanella, Luca / Tuncel, Murat / Aghaee, Atena / Campenni, Alfredo / Petranović Ovčariček, Petra / De Virgilio, Armando

    Seminars in nuclear medicine

    2024  

    Abstract: Molecular imaging is pivotal in evaluating and managing patients with different thyroid cancer histotypes. The existing, pathology-based, risk stratification systems can be usefully refined, by incorporating tumor-specific molecular and molecular imaging ...

    Abstract Molecular imaging is pivotal in evaluating and managing patients with different thyroid cancer histotypes. The existing, pathology-based, risk stratification systems can be usefully refined, by incorporating tumor-specific molecular and molecular imaging biomarkers with theranostic value, allowing patient-specific treatment decisions. Molecular imaging with different radioactive iodine isotopes (ie, I
    Language English
    Publishing date 2024-03-18
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 120248-0
    ISSN 1558-4623 ; 0001-2998
    ISSN (online) 1558-4623
    ISSN 0001-2998
    DOI 10.1053/j.semnuclmed.2024.01.011
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  5. Article ; Online: Reply to: Comment on "Transoral robotic surgery in oropharyngeal squamous cell carcinoma: A comparative study between da Vinci Single-Port and da Vinci Xi systems".

    Costantino, Andrea / Sampieri, Claudio / Meliante, Piero Giuseppe / De Virgilio, Armando / Kim, Se-Heon

    Oral oncology

    2024  Volume 150, Page(s) 106700

    MeSH term(s) Humans ; Squamous Cell Carcinoma of Head and Neck ; Robotic Surgical Procedures ; Head and Neck Neoplasms
    Language English
    Publishing date 2024-02-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 1120465-5
    ISSN 1879-0593 ; 0964-1955 ; 1368-8375
    ISSN (online) 1879-0593
    ISSN 0964-1955 ; 1368-8375
    DOI 10.1016/j.oraloncology.2024.106700
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  6. Article ; Online: The Use of Machine Learning for Predicting Complications of Free Flap Head and Neck Reconstruction: Caution Needed.

    Costantino, Andrea / Festa, Bianca Maria / Spriano, Giuseppe / De Virgilio, Armando

    Annals of surgical oncology

    2023  Volume 30, Issue 7, Page(s) 4232–4233

    MeSH term(s) Humans ; Free Tissue Flaps/adverse effects ; Free Tissue Flaps/surgery ; Plastic Surgery Procedures/adverse effects ; Neck/surgery ; Machine Learning ; Head and Neck Neoplasms/surgery ; Retrospective Studies ; Postoperative Complications/etiology ; Postoperative Complications/surgery
    Language English
    Publishing date 2023-03-30
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 1200469-8
    ISSN 1534-4681 ; 1068-9265
    ISSN (online) 1534-4681
    ISSN 1068-9265
    DOI 10.1245/s10434-023-13428-0
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  7. Article ; Online: Neo-adjuvant chemotherapy and transoral robotic surgery in locoregionally advanced oropharyngeal cancer.

    Costantino, Andrea / Sampieri, Claudio / De Virgilio, Armando / Kim, Se-Heon

    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

    2023  Volume 49, Issue 12, Page(s) 107121

    Abstract: Purpose: To analyze the oncological outcomes and patterns of recurrence of patients with locoregionally advanced oropharyngeal squamous cell carcinoma (OPSCC) who underwent neo-adjuvant chemotherapy (NCT) with subsequent transoral robotic surgery (TORS). ...

    Abstract Purpose: To analyze the oncological outcomes and patterns of recurrence of patients with locoregionally advanced oropharyngeal squamous cell carcinoma (OPSCC) who underwent neo-adjuvant chemotherapy (NCT) with subsequent transoral robotic surgery (TORS).
    Methods: A single-center retrospective cohort study was performed, including 198 patients (mean age: 58.6, SD: 9.2). The primary outcome was disease-free survival (DFS).
    Results: The median follow-up time was 26.5 months (IQR: 16.0-52.0). Estimated DFS rates (95 % CI) at 1 and 3 years were 86.6 % (81.9-91.7), and 81.4 % (75.7-87.6), respectively. Estimated DSS rates (95 % CI) at 1 and 3 years were 96.7 % (94.1-99.3), and 92.6 % (88.4-97.0), respectively. Estimated OS rates (95 % CI) at 1 and 3 years were 96.2 % (93.4-99.0), and 88.7 % (83.4-94.2), respectively. A total of 31 (15.6 %) patients showed a disease relapse after a median time of 8 months (IQR: 4.0-12.0), but only 12 (6 %) patients died of the disease during the study period.
    Conclusions: This study demonstrates that NCT and TORS can obtain excellent tumor control and survival in locoregionally advanced OPSCC. NCT might reduce the need for adjuvant treatments, and randomized clinical trials should be conducted to better define this aspect.
    MeSH term(s) Humans ; Middle Aged ; Carcinoma, Squamous Cell/drug therapy ; Carcinoma, Squamous Cell/surgery ; Retrospective Studies ; Robotic Surgical Procedures/methods ; Neoadjuvant Therapy ; Neoplasm Recurrence, Local ; Squamous Cell Carcinoma of Head and Neck ; Oropharyngeal Neoplasms/drug therapy ; Oropharyngeal Neoplasms/surgery ; Head and Neck Neoplasms
    Language English
    Publishing date 2023-10-18
    Publishing country England
    Document type Journal Article
    ZDB-ID 632519-1
    ISSN 1532-2157 ; 0748-7983
    ISSN (online) 1532-2157
    ISSN 0748-7983
    DOI 10.1016/j.ejso.2023.107121
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  8. Article ; Online: Caution Regarding Assessment of Toxic Effects and Survival in Treatment De-escalation With Radiotherapy vs Transoral Surgery for Human Papillomavirus-Associated Oropharyngeal Cancer.

    De Virgilio, Armando / Costantino, Andrea / Spriano, Giuseppe

    JAMA oncology

    2022  Volume 8, Issue 10, Page(s) 1511–1512

    MeSH term(s) Humans ; Papillomaviridae ; Alphapapillomavirus ; Oropharyngeal Neoplasms/radiotherapy ; Oropharyngeal Neoplasms/surgery ; Papillomavirus Infections/surgery
    Language English
    Publishing date 2022-08-18
    Publishing country United States
    Document type Journal Article ; Comment
    ISSN 2374-2445
    ISSN (online) 2374-2445
    DOI 10.1001/jamaoncol.2022.3458
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  9. Article ; Online: Near-Infrared Spectroscopy for Continuous Noninvasive Monitoring of Free Flap in Head and Neck Reconstruction: Systematic Review of the Literature and Personal Experience.

    Festa, Bianca Maria / Costantino, Andrea / Pace, Gian Marco / Spriano, Giuseppe / De Virgilio, Armando

    Surgical innovation

    2023  Volume 30, Issue 6, Page(s) 711–719

    Abstract: Background: Buried free flaps represent a reconstructive challenge concerning monitoring of vitality, which is fundamental for an early detection of flap failure and prompt surgical salvage. Many flap monitoring techniques have been developed over time, ...

    Abstract Background: Buried free flaps represent a reconstructive challenge concerning monitoring of vitality, which is fundamental for an early detection of flap failure and prompt surgical salvage. Many flap monitoring techniques have been developed over time, and there is still no consensus concerning the best monitoring technique for buried reconstructions.
    Methods: We performed a systematic review of the literature on NIRS monitoring for head and neck free flaps. Moreover, we presented a case of orbital reconstruction through a buried free myo-fascial anterolateral tight flap (ALTF) in which postoperative monitoring was performed by means of NIRS.
    Results: Four studies were included with a total of 200 monitored head and neck free flap reconstructions. Flap survival was reported in 96.5% of studies (n = 193/200) with a 3.5% of total flap failure rate (n = 7/200). We monitored the buried myo-fascial ALTF for 7 post-operative days measuring a regional oxygen saturation (rSO
    Conclusions: This device appeared to be an efficient choice for monitoring buried flaps, thanks to its ability to measure tissue perfusion deep under the skin, to the continuous availability of recorded data on the monitor, and to its low impact on the patient. Further prospective studies are advised in order to standardize this monitoring technique and define warning values.
    MeSH term(s) Humans ; Free Tissue Flaps ; Prospective Studies ; Spectroscopy, Near-Infrared/methods ; Plastic Surgery Procedures ; Neck ; Retrospective Studies
    Language English
    Publishing date 2023-10-25
    Publishing country United States
    Document type Systematic Review ; Case Reports ; Journal Article
    ZDB-ID 2182571-3
    ISSN 1553-3514 ; 1553-3506
    ISSN (online) 1553-3514
    ISSN 1553-3506
    DOI 10.1177/15533506231209128
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  10. Article ; Online: Compartmental Transoral Robotic Lateral Oropharyngectomy with the da Vinci Single-Port System: Surgical Technique.

    De Virgilio, Armando / Costantino, Andrea / Festa, Bianca Maria / Sampieri, Claudio / Spriano, Giuseppe / Kim, Se-Heon

    Annals of surgical oncology

    2023  Volume 30, Issue 9, Page(s) 5728–5732

    Abstract: Background: Transoral robotic surgery (TORS) has renovated the surgical management of oropharyngeal squamous cell carcinoma (OPSCC), allowing a minimally invasive surgical approach with optimal oncological outcomes. The recent introduction of the da ... ...

    Abstract Background: Transoral robotic surgery (TORS) has renovated the surgical management of oropharyngeal squamous cell carcinoma (OPSCC), allowing a minimally invasive surgical approach with optimal oncological outcomes. The recent introduction of the da Vinci Single Port (SP) system resulted in a considerable improvement of TORS technique.
    Methods: In this video, we illustrate the transoral robotic lateral oropharyngectomy performed with the da Vinci SP system in a 50-year-old male patient suffering from a p16+ oropharyngeal squamous cell carcinoma cT4N1M0.
    Results: The transoral robotic lateral oropharyngectomy is illustrated step by step. The structures encountered during the resection are described, and the surgical margins are defined based on anatomical landmarks. The most critical regions encountered during resection are pointed out, and the tip and tricks of this surgery are reported.
    Conclusions: A step-by-step transoral lateral oropharyngectomy is described to increase its reproducibility. The da Vinci SP system owns various benefits for performing transoral lateral oropharyngectomy due to the increased maneuverability in the narrower oral cavity working spaces.
    MeSH term(s) Male ; Humans ; Middle Aged ; Squamous Cell Carcinoma of Head and Neck ; Robotic Surgical Procedures/methods ; Reproducibility of Results ; Mouth/surgery ; Mouth/pathology ; Head and Neck Neoplasms ; Oropharyngeal Neoplasms/surgery ; Oropharyngeal Neoplasms/pathology
    Language English
    Publishing date 2023-07-06
    Publishing country United States
    Document type Video-Audio Media ; Case Reports ; Journal Article
    ZDB-ID 1200469-8
    ISSN 1534-4681 ; 1068-9265
    ISSN (online) 1534-4681
    ISSN 1068-9265
    DOI 10.1245/s10434-023-13735-6
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