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  1. Book ; Online: Interorganizational Diffusion in International Relations : Regional Institutions and the Role of the European Union

    Lenz, Tobias

    2021  

    Keywords International relations ; Comparative politics ; Regional government ; EU & European institutions ; Public administration ; regional organizations, diffusion, institutional design, institutional change, contractual open-endedness, EU, Mercosur, SADC, ASEAN, NAFTA, mixed methods
    Size 1 electronic resource (288 pages)
    Publisher Oxford University Press
    Publishing place Oxford
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021051001
    ISBN 9780198823827 ; 0198823827
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book: Exploratives Sandspiel

    Lenz, Tanja / Fleck, Ingrid

    Wege zur Resilienz

    2020  

    Author's details Tanja Lenz, Ingrid Fleck
    Keywords Sandspiel ; Sandbild ; C. G. Jung ; Sandbildgestaltung ; Therapie ; psychische Entwicklung ; Bindung ; Vulnerabilität ; Psychotherapie ; Trauma ; posttraumatische Belastungsstörung ; PTBS ; Resilienz ; Resilienzforschung ; therapeutisches Gefäß ; Schutzraum ; innere Sicherheit ; analytische Psychologie ; unbewusst ; Schizophrenie ; Differentielle Psychologie und Persönlichkeitspsychologie und psychologische Diagnostik ; Sandspieltherapie ; Psychisches Trauma
    Subject Widerstandsfähigkeit ; Psychische Widerstandsfähigkeit ; Psychische Widerstandskraft ; Sandbaukasten ; Sandspiel-Therapie ; Behandlung ; Psychologische Behandlung ; Psychische Traumatisierung ; Psychotrauma ; Trauma
    Language German
    Size 146 Seiten, Illustrationen
    Publisher Waxmann
    Publishing place Münster ; New York
    Publishing country Germany
    Document type Book
    HBZ-ID HT020473706
    ISBN 978-3-8309-4157-6 ; 3-8309-4157-9 ; 9783830991571 ; 3830991576
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2020 A 1032 available for loan (reading room) Lesesaal EG

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  3. Article ; Online: Phenylsilver - an unexpected one-dimensional coordination polymer of silver(I) tetrads.

    Lenz, Tabea / Hebenbrock, Marian

    Dalton transactions (Cambridge, England : 2003)

    2024  Volume 53, Issue 2, Page(s) 423–427

    Abstract: Herein we present the structures of two distinct one-dimensional coordination polymers of phenylsilver. Both polymers consist of phenylsilver tetrads inter- ... ...

    Abstract Herein we present the structures of two distinct one-dimensional coordination polymers of phenylsilver. Both polymers consist of phenylsilver tetrads inter-connected
    Language English
    Publishing date 2024-01-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 1472887-4
    ISSN 1477-9234 ; 1364-5447 ; 0300-9246 ; 1477-9226
    ISSN (online) 1477-9234 ; 1364-5447
    ISSN 0300-9246 ; 1477-9226
    DOI 10.1039/d3dt03007e
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Behandlung der Nierenarterienstenose im Jahr 2021.

    Lenz, Tomas

    Der Internist

    2021  Volume 62, Issue 3, Page(s) 252–262

    Abstract: Severe arteriosclerotic stenosis of the renal artery with at least 60-70% narrowing of the lumen can lead to various diseases: in the case of unilateral stenosis it can lead to renovascular hypertension, in the case of bilateral narrowing (or in a ... ...

    Title translation Treatment of renal artery stenosis in the year 2021.
    Abstract Severe arteriosclerotic stenosis of the renal artery with at least 60-70% narrowing of the lumen can lead to various diseases: in the case of unilateral stenosis it can lead to renovascular hypertension, in the case of bilateral narrowing (or in a stenotic solitary kidney) also to an often progressive renal insufficiency (ischemic kidney disease) and/or to acute pulmonary edema (pulmonary flash edema). Renal artery stenosis may be treated by revascularization using either percutaneous (balloon angioplasty with or without stenting) or less commonly open surgical procedures, both with excellent primary patency rates of over 90%; however, randomized trials of catheter-based interventions have failed to demonstrate a longer term benefit with respect to blood pressure control and renal function as well as improved overall survival over optimal medicinal management alone. Due to improved clinical outcomes interventional revascularization is justified in cases with critical stenoses and clinical sequelae, such as pulmonary flash edema and progressive renal failure. Careful patient selection is essential to maximize a potential clinical benefit.
    MeSH term(s) Angioplasty ; Humans ; Hypertension, Renovascular/etiology ; Renal Artery/pathology ; Renal Artery Obstruction/complications ; Renal Artery Obstruction/surgery ; Stents ; Treatment Outcome
    Language German
    Publishing date 2021-01-18
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 2913-0
    ISSN 1432-1289 ; 0020-9554
    ISSN (online) 1432-1289
    ISSN 0020-9554
    DOI 10.1007/s00108-020-00935-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.380: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Ischämische Nephropathie und Nierenarterienstenose.

    Lenz, T

    Der Internist

    2015  Volume 56, Issue 3, Page(s) 248–254

    Abstract: Severe renal artery stenosis may cause renovascular hypertension; in case of bilateral narrowing or in a stenotic solitary or transplant kidney, renal insufficiency (ischemic renal disease) or rarely pulmonary flash edema may occur. In most cases ... ...

    Title translation Ischemic renal disease and renal artery stenosis.
    Abstract Severe renal artery stenosis may cause renovascular hypertension; in case of bilateral narrowing or in a stenotic solitary or transplant kidney, renal insufficiency (ischemic renal disease) or rarely pulmonary flash edema may occur. In most cases arteriosclerotic disease is the underlying cause; less prevalent are the various manifestations of fibromuscular disease. Renal artery stenosis may be treated by revasularization, using either percutaneous (balloon angioplasty, stenting) or rarely open surgical procedures, both with excellent primary patency rates. However, randomized trials of renal artery angioplasty or stenting in patients with arteriosclerotic lesions have failed to demonstrate a longer-term benefit with regard to hypertension control and renal dysfunction over medical management alone. Careful patient selection is essential to maximize the potential benefit (e.g., in patients with refractory hypertension, progressive renal failure or recurrent pulmonary flash edema).
    MeSH term(s) Humans ; Hypertension, Renal/diagnosis ; Hypertension, Renal/etiology ; Hypertension, Renal/prevention & control ; Ischemia/complications ; Ischemia/diagnosis ; Ischemia/surgery ; Kidney/blood supply ; Renal Artery Obstruction/complications ; Renal Artery Obstruction/diagnosis ; Renal Artery Obstruction/surgery ; Treatment Outcome ; Vascular Surgical Procedures/methods
    Language German
    Publishing date 2015-03
    Publishing country Germany
    Document type English Abstract ; Journal Article
    ZDB-ID 2913-0
    ISSN 1432-1289 ; 0020-9554
    ISSN (online) 1432-1289
    ISSN 0020-9554
    DOI 10.1007/s00108-014-3573-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.380: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Reply: Targeting Inflammation and Immunology: A Hope for the Frequent Flyers?

    Lenz, Tobias / Koch, Tobias / Kufner, Sebastian

    JACC. Cardiovascular interventions

    2024  Volume 17, Issue 7, Page(s) 948

    MeSH term(s) Humans ; Treatment Outcome ; Inflammation
    Language English
    Publishing date 2024-04-10
    Publishing country United States
    Document type Letter
    ZDB-ID 2452157-7
    ISSN 1876-7605 ; 1936-8798
    ISSN (online) 1876-7605
    ISSN 1936-8798
    DOI 10.1016/j.jcin.2024.02.018
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6669: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  7. Book ; Online: Reflection for Tuesday, June 30, 2020

    Lenz, Tom

    13th week in Ordinary Time. ; Daily Reflections (Meditations) on the Scriptures from the Roman Catholic Lectionary.

    2020  

    Abstract: Today's story in Matthew's gospel is likely a familiar one to most people. Jesus goes out in a boat with his disciples and the sea's turn for the worse. The disciples are scared and believe they may die and all the while Jesus is asleep. They call on ... ...

    Abstract |Today's story in Matthew's gospel is likely a familiar one to most people. Jesus goes out in a boat with his disciples and the sea's turn for the worse. The disciples are scared and believe they may die and all the while Jesus is asleep. They call on him to wake up. I can picture myself on that boat as the sky turns dark, the winds blow hard as the waves come up over the sides of the boat. I would be terrified, no doubt. After I read the story, however, the familiarity of it changed as I became fixed on the idea of Jesus being asleep while all this was going on.|Many of my thoughts these days seem to focus on racism and the struggles that people of color experience in today's world. I think about being a white man and how I have greatly benefited from those two unearned characteristics. I have done nothing to earn the many privileges that just seem to be part of my normal life. For most of my life I just kind of assumed everyone lived like me and had the same opportunities and benefits that I did. I am beginning to understand, however, that this is not so – and unfortunately, far from the true life experiences of my brothers and sisters of color. I have been asleep while the storm blew all around me.|Racism, sexism, consumerism, war, disease, politics, and other noxious doings of life today foster a sense of dualism – or a separation of humanity where we do not see our similarities, but only our differences. If there were ever a time when we should recognize the sameness of all humanity, it should be now. The COVID-19 virus does not discriminate based on color, race, gender, or political alliance. Nor too, do the feelings of hurt and anger after watching people of color murdered by those with power and privilege.|The storm of racism and injustice isn't scary to those who are asleep. The inability to see the happenings of today, either by choice or by ignorance, is a position of unearned privilege. It is time to wake from our sleep and take action to calm the storm – just as Jesus did. It's time for everyone who has been asleep to get up and rebuke the wind and the sea, and perhaps then we can have great calm.
    Keywords Amos 3:1-8 ; 4:11-12 ; Psalms 5:4b-6a ; 6b-7 ; 8 ; Matthew 8:23-27 ; covid19
    Subject code 230
    Language English
    Publishing date 2020-06-30
    Publisher University Ministry, Creighton University.
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Book ; Online: Reflection for Saturday, April 25, 2020

    Lenz, Thomas

    Saint Mark, Evangelist. ; Daily Reflections (Meditations) on the Scriptures from the Roman Catholic Lectionary.

    2020  

    Abstract: My reflection on the readings of the day usually draw me towards the gospel. Today's gospel reading from Mark certainly has a great deal of good stuff to reflect upon as Jesus ascends into heaven and his disciples go forth and preach everywhere.|But, my ...

    Abstract |My reflection on the readings of the day usually draw me towards the gospel. Today's gospel reading from Mark certainly has a great deal of good stuff to reflect upon as Jesus ascends into heaven and his disciples go forth and preach everywhere.|But, my attention from today's readings are drawing me to Peter's first letter. It seems to say so much about what the world is experiencing right here and now. Peter says, "Cast all your worries upon him because he care for you." How perfect for the worries of the newness we live in today. But, Peter goes on to teach us about something that is perhaps as equally important - our sameness with one another. A few lines later he says, "…knowing that your brothers and sisters throughout the world undergo the same sufferings." If there is one positivity that we can take away from this pandemic is the realization of our sameness in our humanity.|Sometimes our fast-paced lives cause us to get caught up inside the issues of our personal lives only. It's easy to feel like our problems are worse than others. This "otherness" leads to an individualistic view and does not allow us to see the interconnections among all of us. It doesn't allow us to see that we are just part of the whole, rather than being "the whole". Peter reminds us that people everywhere experience the same difficulties and challenges regardless of where you live. Likewise, the COVID-19 pandemic is teaching us the same. It doesn't matter your gender, race, nationality, socio-economic status, or even political party, no one is immune to the challenges of the day. We are all experiencing physical isolation from one another, anxiety from not knowing what the immediate and long-term future holds, and perhaps a longing for "the good 'ol days" of pre-pandemic life. But, knowing that we are not suffering inside of our individual-ness is somehow comforting because it allows us to connect with everyone across the globe at a deeper level. And, perhaps if we reflect upon that notion for long enough, we can realize that in order for us to feel whole as an individual, we need to paradoxically come to terms with the idea that we are only part of the whole and share the greater wholeness with the rest of humanity.
    Keywords Saint Mark ; evangelist ; 1 Peter 5:5b-14 ; Psalms 89:2-3 ; 6-7 ; 16-17 ; Mark 16:15-20 ; covid19
    Subject code 120
    Language English
    Publishing date 2020-04-25
    Publisher University Ministry, Creighton University.
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Book ; Thesis: Langzeitanalyse intertrochantärer Korrekturosteotomien bei posttraumatischen Veränderungen

    Lenz, Thomas

    1998  

    Author's details vorgelegt von Thomas Lenz
    Language German
    Size 96 Bl. : Ill., graph. Darst.
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Bochum, Univ., Diss., 1999
    HBZ-ID HT011090731
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    99 E 2481 order for loan Magazin

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  10. Article ; Online: S

    Lenz, Thomas / Stühler, Kai

    International journal of molecular sciences

    2022  Volume 23, Issue 10

    Abstract: Chemical biology and the application of small molecules has proven to be a potent perturbation strategy, especially for the functional elucidation of proteins, their networks, and regulators. In recent years, the cellular thermal shift assay (CETSA) and ... ...

    Abstract Chemical biology and the application of small molecules has proven to be a potent perturbation strategy, especially for the functional elucidation of proteins, their networks, and regulators. In recent years, the cellular thermal shift assay (CETSA) and its proteome-wide extension, thermal proteome profiling (TPP), have proven to be effective tools for identifying interactions of small molecules with their target proteins, as well as off-targets in living cells. Here, we asked the question whether isothermal dose-response (ITDR) CETSA can be exploited to characterize secondary effects downstream of the primary binding event, such as changes in post-translational modifications or protein-protein interactions (PPI). By applying ITDR-CETSA to MAPK14 kinase inhibitor treatment of living HL-60 cells, we found similar dose-responses for the direct inhibitor target and its known interaction partners MAPKAPK2 and MAPKAPK3. Extension of the dose-response similarity comparison to the proteome wide level using TPP with compound concentration range (TPP-CCR) revealed not only the known MAPK14 interaction partners MAPKAPK2 and MAPKAPK3, but also the potentially new intracellular interaction partner MYLK. We are confident that dose-dependent small molecule treatment in combination with ITDR-CETSA or TPP-CCR similarity assessment will not only allow discrimination between primary and secondary effects, but will also provide a novel method to study PPI in living cells without perturbation by protein modification, which we named "small molecule arranged thermal proximity coaggregation" (smarTPCA).
    MeSH term(s) Humans ; Mitogen-Activated Protein Kinase 14 ; Proteome/metabolism
    Chemical Substances Proteome ; Mitogen-Activated Protein Kinase 14 (EC 2.7.11.24)
    Language English
    Publishing date 2022-05-17
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms23105605
    Database MEDical Literature Analysis and Retrieval System OnLINE

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