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  1. Article: Outcomes Following Pedestal Cup Reconstruction of (Impending) Pathological Fractures of the Acetabulum due to Metastatic Bone Disease.

    Macdonald, J / Baird, C / Jeys, L / Parry, M / Stevenson, J

    Indian journal of surgical oncology

    2024  Volume 15, Issue 2, Page(s) 428–436

    Abstract: Management of periacetabular metastatic bone disease (MBD) is challenging, specifically if associated with bone loss or fracture. The aim of this study was to evaluate the complications and outcomes after undergoing peri-acetabular reconstruction using ... ...

    Abstract Management of periacetabular metastatic bone disease (MBD) is challenging, specifically if associated with bone loss or fracture. The aim of this study was to evaluate the complications and outcomes after undergoing peri-acetabular reconstruction using an 'ice-cream cone' pedestal cup endoprostheses for the most severe cases of (impending) pathological acetabular fractures. Fifty cases with severe periacetabular disease were identified. Acetabular defects were classified using the Metastatic Acetabular Classification (MAC). Pre- and post-operative mobility was assessed using the Eastern Cooperative Oncology Group (ECOG) Performance Status. Pain levels were assessed using a verbal rating scale. Surgical complications and patient survival were analysed; the Prognostic Immune Nutritional Index (PINI) was applied retrospectively to survival. There were 32 females and 18 males with a median age of 65 (41-88). Median post-operative follow-up was 16 months (IQR 5.5-28.5 months). Thirty-nine had complete, and 11, impending pathological fractures. The observed five-year survival was 19%, with a median survival of 16 months (IQR 5.8-42.5 months). Significantly worse survival was observed with PINI scores < 3.0 (
    Supplementary information: The online version contains supplementary material available at 10.1007/s13193-024-01917-x.
    Language English
    Publishing date 2024-03-16
    Publishing country India
    Document type Journal Article
    ZDB-ID 2568289-1
    ISSN 0976-6952 ; 0975-7651
    ISSN (online) 0976-6952
    ISSN 0975-7651
    DOI 10.1007/s13193-024-01917-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Book ; Online ; E-Book: Our warming planet

    Rosenzweig, Cynthia / Parry, Martin L. / De Mel, Manishka

    climate change impacts and adaptation

    (Lectures in climate change ; vol. 2)

    2022  

    Author's details editors: Cynthia Rosenzweig (NASA Goddard Institute for Space Studies, USA & Columbia University, USA), Martin Parry (Imperial College London, UK), Manishka De Mel (Columbia University, USA & NASA Goddard Institute for Space Studies, USA)
    Series title Lectures in climate change ; vol. 2
    Collection
    Keywords Global warming ; Climatic changes
    Language English
    Size 1 Online-Ressource (xxiv, 682 Seiten), Illustrationen
    Publisher World Scientific
    Publishing place Singapore
    Publishing country Singapore
    Document type Book ; Online ; E-Book
    Note Includes bibliographical references
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT021192120
    ISBN 978-981-12-3822-2 ; 9789811238239 ; 9789811238215 ; 9789811239298 ; 981-12-3822-7 ; 9811238235 ; 9811238219 ; 9811239290
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Article ; Online: Caregiver Burden and Cardiovascular Disease: Can We Afford to Keep the Health of Caregivers in Canada Invisible?

    Parry, Monica

    The Canadian journal of cardiology

    2019  Volume 35, Issue 10, Page(s) 1267–1269

    MeSH term(s) Adaptation, Psychological ; Canada ; Cardiovascular Diseases ; Caregivers ; Cost of Illness ; Humans ; Risk Factors
    Language English
    Publishing date 2019-09-09
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 632813-1
    ISSN 1916-7075 ; 0828-282X
    ISSN (online) 1916-7075
    ISSN 0828-282X
    DOI 10.1016/j.cjca.2019.06.025
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  4. Article: Introducing the Metastatic Breast Cancer Project: a novel patient-partnered initiative to accelerate understanding of MBC.

    Parry, Marina

    ESMO open

    2018  Volume 3, Issue 7, Page(s) e000452

    Language English
    Publishing date 2018-11-01
    Publishing country England
    Document type Journal Article
    ISSN 2059-7029
    ISSN 2059-7029
    DOI 10.1136/esmoopen-2018-000452
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  5. Article: Tumor evolution in non-small-cell lung cancer.

    Parry, Marina

    ESMO open

    2018  Volume 3, Issue 6, Page(s) e000436

    Language English
    Publishing date 2018-09-25
    Publishing country England
    Document type Journal Article
    ISSN 2059-7029
    ISSN 2059-7029
    DOI 10.1136/esmoopen-2018-000436
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  6. Article: Intramuscular ossifying metastasis from oesophageal carcinoma, with a pattern distinct from myositis ossificans - A case report.

    Freer, F / Parry, M / Botchu, R

    Journal of clinical orthopaedics and trauma

    2021  Volume 24, Page(s) 101725

    Abstract: Muscle metastasis is uncommon. We present second reported case of ossifying metastasis from oesophageal carcinoma and review the literature. Our case highlights the different patterns of ossification in muscle, which is essential to make the diagnosis of ...

    Abstract Muscle metastasis is uncommon. We present second reported case of ossifying metastasis from oesophageal carcinoma and review the literature. Our case highlights the different patterns of ossification in muscle, which is essential to make the diagnosis of myositis ossificans, a "don't touch lesion" in contrast to muscle metastasis or tumour, that needs oncological management.
    Language English
    Publishing date 2021-11-29
    Publishing country India
    Document type Case Reports
    ZDB-ID 2596956-0
    ISSN 2213-3445 ; 0976-5662
    ISSN (online) 2213-3445
    ISSN 0976-5662
    DOI 10.1016/j.jcot.2021.101725
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  7. Article: Providing compassionate care in a virtual context: Qualitative exploration of Canadian primary care nurses' experiences.

    Rouleau, Geneviève / Wu, Kelly / Parry, Monica / Richard, Lauralie / Desveaux, Laura

    Digital health

    2024  Volume 10, Page(s) 20552076231224072

    Abstract: Objective: Virtual care presents a promising opportunity to create new communication channels and increase access to healthcare. However, concerns have been raised around the potential for unintended emotional distances created through virtual care ... ...

    Abstract Objective: Virtual care presents a promising opportunity to create new communication channels and increase access to healthcare. However, concerns have been raised around the potential for unintended emotional distances created through virtual care environments that could strain patient-provider relationships. While compassionate care is an enabler of emotional connectivity and a core tenant of nursing, little is known about whether or how nurses have adapted their compassion skills into virtual interactions. These concerns are particularly relevant in primary care, where there is a focus on relational continuity (i.e. relationship-based, longitudinal care) and a broad uptake of virtual care. The aim of this study was to explore the meaning of compassionate virtual care and to uncover how nurses operationalized compassionate care through virtual interactions in primary care.
    Methods: We used a qualitative interpretive descriptive lens to conduct semistructured interviews with primary care nurses (Ontario, Canada) who had provided virtual care (i.e. video visits, remote patient monitoring, or asynchronous messaging). We used a thematic approach to analyze the data.
    Results: We interviewed 18 nurse practitioners and two registered nurses. Participants described how: (1) compassionate care was central to nursing practice, (2) compassionate care was evolving through virtual nurse-patient interaction, and (3) nurses balanced practice with patients' expectations while providing virtual compassionate care.
    Conclusions: There is an opportunity to better align nurses' understanding and operationalization of compassionate care in virtual primary care contexts. Exploring how compassionate care is operationalized in primary care settings is a necessary first step to building compassionate competencies across the nursing profession to support the continued virtual evolution of health service delivery.
    Language English
    Publishing date 2024-01-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2819396-9
    ISSN 2055-2076
    ISSN 2055-2076
    DOI 10.1177/20552076231224072
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Health locus of control and self-management behaviours among individuals with ischaemic heart disease: protocol for a scoping review.

    Wang, Run / Zhou, Chunlan / Parry, Monica

    BMJ open

    2023  Volume 13, Issue 10, Page(s) e075277

    Abstract: Introduction: Ischaemic heart disease is a significant cause of morbidity and mortality worldwide. Self-management is a way to reduce the risk associated with ischaemic heart disease; however, some individuals may not have the ability or willingness to ... ...

    Abstract Introduction: Ischaemic heart disease is a significant cause of morbidity and mortality worldwide. Self-management is a way to reduce the risk associated with ischaemic heart disease; however, some individuals may not have the ability or willingness to engage in self-management behaviours. One approach to identify an individual's readiness and capacity to engage in self-management behaviours is to assess their health locus of control. Based on the Individual and Family Self-Management Theory, this review's objectives are to describe: (1) how health locus of control affects the process of engaging in self-management behaviours, (2) impacts of health locus of control on outcomes associated with self-management behaviours and (3) potential contextual variations in the relationship between health locus of control and self-management behaviours.
    Methods and analysis: The scoping review will be guided by the Joanna Briggs Institute methodological framework. A comprehensive search will encompass seven electronic databases (Ovid Medline, CINAHL, EMBASE, APA PsycINFO, Cochrane Database of Systematic Reviews, Cochrane Central Register of Controlled Trials, Scopus) and grey literature sources (ProQuest Dissertations, ClinicalTrials.gov). Collaborative efforts with library experts will inform our search strategies, building on insights from previous reviews centred on self-management and ischaemic heart disease. Two review authors will independently conduct the screening and data extraction processes; discrepancies will be resolved through consensus or discussion with a third review author. The review will include English studies from database inception, focusing on the health locus of control among adults with ischaemic heart disease. Findings will be presented graphically and tabularly, together with a narrative description.
    Ethics and dissemination: We will collect data from published and grey literature, meaning ethical approval is not necessary. Findings will be published in peer-reviewed journals and presented at academic conferences.
    Registration details: Open Science Framework (https://doi.org/10.17605/OSF.IO/B4A6F).
    MeSH term(s) Adult ; Humans ; Self-Management ; Internal-External Control ; Systematic Reviews as Topic ; Myocardial Ischemia/therapy ; Research Design ; Review Literature as Topic
    Language English
    Publishing date 2023-10-17
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2599832-8
    ISSN 2044-6055 ; 2044-6055
    ISSN (online) 2044-6055
    ISSN 2044-6055
    DOI 10.1136/bmjopen-2023-075277
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Application of deep learning in cancer epigenetics through DNA methylation analysis.

    Yassi, Maryam / Chatterjee, Aniruddha / Parry, Matthew

    Briefings in bioinformatics

    2023  Volume 24, Issue 6

    Abstract: DNA methylation is a fundamental epigenetic modification involved in various biological processes and diseases. Analysis of DNA methylation data at a genome-wide and high-throughput level can provide insights into diseases influenced by epigenetics, such ...

    Abstract DNA methylation is a fundamental epigenetic modification involved in various biological processes and diseases. Analysis of DNA methylation data at a genome-wide and high-throughput level can provide insights into diseases influenced by epigenetics, such as cancer. Recent technological advances have led to the development of high-throughput approaches, such as genome-scale profiling, that allow for computational analysis of epigenetics. Deep learning (DL) methods are essential in facilitating computational studies in epigenetics for DNA methylation analysis. In this systematic review, we assessed the various applications of DL applied to DNA methylation data or multi-omics data to discover cancer biomarkers, perform classification, imputation and survival analysis. The review first introduces state-of-the-art DL architectures and highlights their usefulness in addressing challenges related to cancer epigenetics. Finally, the review discusses potential limitations and future research directions in this field.
    MeSH term(s) Humans ; DNA Methylation ; Deep Learning ; Epigenesis, Genetic ; Genome ; Neoplasms/genetics
    Language English
    Publishing date 2023-11-20
    Publishing country England
    Document type Systematic Review ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2068142-2
    ISSN 1477-4054 ; 1467-5463
    ISSN (online) 1477-4054
    ISSN 1467-5463
    DOI 10.1093/bib/bbad411
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  10. Article ; Online: Telephone consultations to manage paediatric outpatient clinics during the COVID-19 pandemic: a service evaluation.

    Edwards, Lowri M / Parry, Mair

    Irish journal of medical science

    2021  Volume 191, Issue 3, Page(s) 977–983

    Abstract: Background: North West Wales is predominantly rural with a relatively small population spread over a large geographical area. The rapid development of the COVID-19 pandemic led to a radical re-thinking of how to provide continuing paediatric outpatient ... ...

    Abstract Background: North West Wales is predominantly rural with a relatively small population spread over a large geographical area. The rapid development of the COVID-19 pandemic led to a radical re-thinking of how to provide continuing paediatric outpatient care in the face of a lockdown. The solution adopted was to use telephone consultations.
    Aims: This study took place during the summer of 2020, after the first lockdown had been relaxed. The purpose of this study was to evaluate the acceptability of telephone consultations as an alternative to conventional paediatric outpatient appointments and assess whether it could continue to have a useful role beyond the pandemic.
    Methods: Two hundred ninety-five telephone surveys were conducted with respondents, most of whom were carers of paediatric outpatients. Questions explored the child's underlying condition, respondents' attitudes towards the service received, social factors including distance previously travelled to the hospital and whether they would find ongoing telephone review acceptable or not.
    Results: Sixty-one percent of respondents expressed a positive interest in ongoing telephone consultations. They commented particularly on compatibility with work commitments, childcare arrangements and travel times. Those travelling more than 1 h were particularly positive in their support. Respondents expressed the continued need for face-to-face review if the child's condition changed acutely.
    Conclusion: Telephone consultations are an acceptable means of improving clinic punctuality, accessibility and convenience for families in rural areas, with ongoing potential beyond the pandemic. Careful consideration is required of the individual's needs and requirement for physical examination when extending the use of telephone consultations.
    MeSH term(s) Ambulatory Care Facilities ; COVID-19 ; Child ; Communicable Disease Control ; Humans ; Pandemics ; Referral and Consultation ; Telemedicine ; Telephone
    Language English
    Publishing date 2021-06-07
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 390895-1
    ISSN 1863-4362 ; 0021-1265
    ISSN (online) 1863-4362
    ISSN 0021-1265
    DOI 10.1007/s11845-021-02672-6
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