LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Back to previous search Search history
Advanced search

Your last searches

  1. AU="Richieri, Peter"
  2. AU="Panchbhaya, Yasmin N."
  3. AU="Menier, C"
  4. AU="Hikosaka, Okihide"
  5. AU="Taylor, John A"
  6. AU="Weidenhammer, Christian"
  7. AU="Cheema, Marvi"
  8. AU="Chen, Dashu"
  9. AU="Meyer, Birgit"
  10. AU="Palle, Pushpalatha"
  11. AU="Rajendran, Krishnan"
  12. AU="Cathleen R. Carlin"
  13. AU="Huang, Florent"
  14. AU="Allen, Paul"
  15. AU=Noknoy Sairat
  16. AU=Hardie William D
  17. AU="de Libero, Cinzia"
  18. AU="Peyro, Mohaddeseh"
  19. AU="Su, Y S"
  20. AU=Li Qiubai AU=Li Qiubai
  21. AU="Xu, Winnie"
  22. AU="Seah, Annabel"
  23. AU="Qv, Zong-Yang"
  24. AU="Lederer, Franziska L"
  25. AU="Funder, John W"
  26. AU="Boyang Zhou"
  27. AU="Karsten Niehaus"
  28. AU=Sakurada Tsutomu
  29. AU="Ravinovich"
  30. AU="Le Corroller, Thomas"
  31. AU=Wang Lihua
  32. AU="Balducci, Ivan"
  33. AU="Kamble, Nitish" AU="Kamble, Nitish"
  34. AU="Violetta Dziedziejko"
  35. AU="Pablo Cañón"
  36. AU="Boone, Darren"
  37. AU="Nadeem S. Sheikh"
  38. AU="Means, Gary"
  39. AU="Tania Kew"
  40. AU="Williams, Scott A"
  41. AU="Dvir, May"

Search results

Result 1 - 2 of total 2

Search options

  1. Article: Spatial analysis of human lung cancer reveals organized immune hubs enriched for stem-like CD8 T cells and associated with immunotherapy response.

    Chen, Jonathan H / Nieman, Linda T / Spurrell, Maxwell / Jorgji, Vjola / Richieri, Peter / Xu, Katherine H / Madhu, Roopa / Parikh, Milan / Zamora, Izabella / Mehta, Arnav / Nabel, Christopher S / Freeman, Samuel S / Pirl, Joshua D / Lu, Chenyue / Meador, Catherine B / Barth, Jaimie L / Sakhi, Mustafa / Tang, Alexander L / Sarkizova, Siranush /
    Price, Colles / Fernandez, Nicolas F / Emanuel, George / He, Jiang / Raay, Katrina Van / Reeves, Jason W / Yizhak, Keren / Hofree, Matan / Shih, Angela / Sade-Feldman, Moshe / Boland, Genevieve M / Pelka, Karin / Aryee, Martin / Korsunsky, Ilya / Mino-Kenudson, Mari / Gainor, Justin F / Hacohen, Nir

    bioRxiv : the preprint server for biology

    2023  

    Abstract: The organization of immune cells in human tumors is not well understood. Immunogenic tumors harbor spatially-localized multicellular 'immunity hubs' defined by expression of the T cell-attracting ... ...

    Abstract The organization of immune cells in human tumors is not well understood. Immunogenic tumors harbor spatially-localized multicellular 'immunity hubs' defined by expression of the T cell-attracting chemokines
    Language English
    Publishing date 2023-04-06
    Publishing country United States
    Document type Preprint
    DOI 10.1101/2023.04.04.535379
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  2. Article ; Online: Human lung cancer harbors spatially organized stem-immunity hubs associated with response to immunotherapy.

    Chen, Jonathan H / Nieman, Linda T / Spurrell, Maxwell / Jorgji, Vjola / Elmelech, Liad / Richieri, Peter / Xu, Katherine H / Madhu, Roopa / Parikh, Milan / Zamora, Izabella / Mehta, Arnav / Nabel, Christopher S / Freeman, Samuel S / Pirl, Joshua D / Lu, Chenyue / Meador, Catherine B / Barth, Jaimie L / Sakhi, Mustafa / Tang, Alexander L /
    Sarkizova, Siranush / Price, Colles / Fernandez, Nicolas F / Emanuel, George / He, Jiang / Van Raay, Katrina / Reeves, Jason W / Yizhak, Keren / Hofree, Matan / Shih, Angela / Sade-Feldman, Moshe / Boland, Genevieve M / Pelka, Karin / Aryee, Martin J / Mino-Kenudson, Mari / Gainor, Justin F / Korsunsky, Ilya / Hacohen, Nir

    Nature immunology

    2024  Volume 25, Issue 4, Page(s) 644–658

    Abstract: The organization of immune cells in human tumors is not well understood. Immunogenic tumors harbor spatially localized multicellular 'immunity hubs' defined by expression of the T cell-attracting chemokines CXCL10/CXCL11 and abundant T cells. Here, we ... ...

    Abstract The organization of immune cells in human tumors is not well understood. Immunogenic tumors harbor spatially localized multicellular 'immunity hubs' defined by expression of the T cell-attracting chemokines CXCL10/CXCL11 and abundant T cells. Here, we examined immunity hubs in human pre-immunotherapy lung cancer specimens and found an association with beneficial response to PD-1 blockade. Critically, we discovered the stem-immunity hub, a subtype of immunity hub strongly associated with favorable PD-1-blockade outcome. This hub is distinct from mature tertiary lymphoid structures and is enriched for stem-like TCF7
    MeSH term(s) Humans ; Lung Neoplasms ; CD8-Positive T-Lymphocytes ; Programmed Cell Death 1 Receptor ; Chemokines/metabolism ; Immunotherapy/methods ; Tumor Microenvironment
    Chemical Substances Programmed Cell Death 1 Receptor ; Chemokines
    Language English
    Publishing date 2024-03-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2016987-5
    ISSN 1529-2916 ; 1529-2908
    ISSN (online) 1529-2916
    ISSN 1529-2908
    DOI 10.1038/s41590-024-01792-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 5294: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MG 42: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top