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  1. Article ; Online: Research progress on the mechanism of ferroptosis in neonatal acute lung injury

    CHU Xiaoyun, CAI Cheng

    Jichu yixue yu linchuang, Vol 43, Iss 6, Pp 1008-

    2023  Volume 1011

    Abstract: Acute lung injury is a common critical illness in neonates. Ferroptosis, a novel form of programmed cell death, plays an important role in the process of acute lung injury by regulating iron homeostasis, metabolism of amino acid and lipid peroxidation. ... ...

    Abstract Acute lung injury is a common critical illness in neonates. Ferroptosis, a novel form of programmed cell death, plays an important role in the process of acute lung injury by regulating iron homeostasis, metabolism of amino acid and lipid peroxidation. In-depth study of the mechanism of ferroptosis in acute lung injury may provide new ideas for its prevention and treatment.
    Keywords ferroptosis|iron homeostasis|metabolism of amino acid|lipid peroxidation|acute lung injury in neonate ; Medicine ; R
    Language Chinese
    Publishing date 2023-06-01T00:00:00Z
    Publisher Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Nanozyme as a rising star for metabolic disease management.

    Wang, Yanan / He, Xiaoyun / Huang, Kunlun / Cheng, Nan

    Journal of nanobiotechnology

    2024  Volume 22, Issue 1, Page(s) 226

    Abstract: Nanozyme, characterized by outstanding and inherent enzyme-mimicking properties, have emerged as highly promising alternatives to natural enzymes owning to their exceptional attributes such as regulation of oxidative stress, convenient storage, ... ...

    Abstract Nanozyme, characterized by outstanding and inherent enzyme-mimicking properties, have emerged as highly promising alternatives to natural enzymes owning to their exceptional attributes such as regulation of oxidative stress, convenient storage, adjustable catalytic activities, remarkable stability, and effortless scalability for large-scale production. Given the potent regulatory function of nanozymes on oxidative stress and coupled with the fact that reactive oxygen species (ROS) play a vital role in the occurrence and exacerbation of metabolic diseases, nanozyme offer a unique perspective for therapy through multifunctional activities, achieving essential results in the treatment of metabolic diseases by directly scavenging excess ROS or regulating pathologically related molecules. The rational design strategies, nanozyme-enabled therapeutic mechanisms at the cellular level, and the therapies of nanozyme for several typical metabolic diseases and underlying mechanisms are discussed, mainly including obesity, diabetes, cardiovascular disease, diabetic wound healing, and others. Finally, the pharmacokinetics, safety analysis, challenges, and outlooks for the application of nanozyme are also presented. This review will provide some instructive perspectives on nanozyme and promote the development of enzyme-mimicking strategies in metabolic disease therapy.
    MeSH term(s) Humans ; Metabolic Diseases/drug therapy ; Metabolic Diseases/metabolism ; Animals ; Reactive Oxygen Species/metabolism ; Oxidative Stress/drug effects ; Nanostructures/chemistry ; Nanostructures/therapeutic use ; Nanoparticles/chemistry ; Enzymes/metabolism ; Diabetes Mellitus/drug therapy ; Diabetes Mellitus/metabolism ; Obesity/metabolism ; Obesity/drug therapy
    Chemical Substances Reactive Oxygen Species ; Enzymes
    Language English
    Publishing date 2024-05-06
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2100022-0
    ISSN 1477-3155 ; 1477-3155
    ISSN (online) 1477-3155
    ISSN 1477-3155
    DOI 10.1186/s12951-024-02478-5
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  3. Article ; Online: The minus strand of positive-sense RNA viruses encodes small proteins.

    Cheng, Xiaofei / Wu, Xiaoyun / Fang, Rongxiang

    Trends in microbiology

    2023  Volume 32, Issue 1, Page(s) 6–7

    Abstract: It is widely accepted that the minus strands of positive single-strand RNA (+ssRNA) viruses function as replication templates only. Gong et al. revealed that the minus strand of two unrelated +ssRNA viruses encodes proteins. This textbook-changing ... ...

    Abstract It is widely accepted that the minus strands of positive single-strand RNA (+ssRNA) viruses function as replication templates only. Gong et al. revealed that the minus strand of two unrelated +ssRNA viruses encodes proteins. This textbook-changing discovery calls for the reconsideration of the molecular mechanisms underlying the infection cycle of +ssRNA viruses.
    MeSH term(s) RNA, Viral/genetics ; RNA, Viral/metabolism ; Virus Replication ; Positive-Strand RNA Viruses/genetics ; Positive-Strand RNA Viruses/metabolism ; RNA Viruses/genetics ; RNA Viruses/metabolism
    Chemical Substances RNA, Viral
    Language English
    Publishing date 2023-11-10
    Publishing country England
    Document type Journal Article
    ZDB-ID 1158963-2
    ISSN 1878-4380 ; 0966-842X
    ISSN (online) 1878-4380
    ISSN 0966-842X
    DOI 10.1016/j.tim.2023.10.012
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3738: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  4. Article ; Online: Activation of peroxymonosulfate with natural pyrite-biochar composite for sulfamethoxazole degradation in soil: Organic matter effects and free radical conversion.

    Zhao, Ranran / Wang, Tianyu / Wang, Zhaowei / Cheng, Wan / Li, Liangyu / Wang, Yaodong / Xie, Xiaoyun

    Journal of hazardous materials

    2024  Volume 469, Page(s) 133895

    Abstract: Peroxymonosulfate (PMS)-based advanced oxidation processes (AOPs) represent an effective method for the remediation of antibiotic-contaminated soils. In this study, a natural pyrite-biochar composite material (FBCx) was developed, demonstrating superior ... ...

    Abstract Peroxymonosulfate (PMS)-based advanced oxidation processes (AOPs) represent an effective method for the remediation of antibiotic-contaminated soils. In this study, a natural pyrite-biochar composite material (FBCx) was developed, demonstrating superior activation performance and achieving a 76% removal rate of SMX from soil within 120 min. There existed different degradation mechanisms for SMX in aqueous and soil solutions, respectively. The production of
    Language English
    Publishing date 2024-02-27
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1491302-1
    ISSN 1873-3336 ; 0304-3894
    ISSN (online) 1873-3336
    ISSN 0304-3894
    DOI 10.1016/j.jhazmat.2024.133895
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  5. Article ; Online: Erythema Multiforme-Like Drug Eruption Associated With Adalimumab Treatment.

    Lei, Mingjun / Niu, Ruiju / Cheng, Xiumei / Zhang, Xiaoyun / Xue, Sisi / Yang, Yinan

    Dermatitis : contact, atopic, occupational, drug

    2023  

    Language English
    Publishing date 2023-08-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2144723-8
    ISSN 2162-5220 ; 1532-8163 ; 1710-3568
    ISSN (online) 2162-5220 ; 1532-8163
    ISSN 1710-3568
    DOI 10.1089/derm.2023.0110
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3680: Show issues Location:
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  6. Article ; Online: Photonic neuromorphic architecture for tens-of-task lifelong learning.

    Cheng, Yuan / Zhang, Jianing / Zhou, Tiankuang / Wang, Yuyan / Xu, Zhihao / Yuan, Xiaoyun / Fang, Lu

    Light, science & applications

    2024  Volume 13, Issue 1, Page(s) 56

    Abstract: Scalable, high-capacity, and low-power computing architecture is the primary assurance for increasingly manifold and large-scale machine learning tasks. Traditional electronic artificial agents by conventional power-hungry processors have faced the ... ...

    Abstract Scalable, high-capacity, and low-power computing architecture is the primary assurance for increasingly manifold and large-scale machine learning tasks. Traditional electronic artificial agents by conventional power-hungry processors have faced the issues of energy and scaling walls, hindering them from the sustainable performance improvement and iterative multi-task learning. Referring to another modality of light, photonic computing has been progressively applied in high-efficient neuromorphic systems. Here, we innovate a reconfigurable lifelong-learning optical neural network (L
    Language English
    Publishing date 2024-02-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 2662628-7
    ISSN 2047-7538 ; 2047-7538
    ISSN (online) 2047-7538
    ISSN 2047-7538
    DOI 10.1038/s41377-024-01395-4
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  7. Article ; Online: LncRNA POU6F2-AS2 contributes to malignant phenotypes and paclitaxel resistance by promoting SKP2 expression in stomach adenocarcinoma.

    Jin, Yanzhao / Cao, Jiaqing / Cheng, Hua / Hu, Xiaoyun

    Journal of chemotherapy (Florence, Italy)

    2023  Volume 35, Issue 7, Page(s) 638–652

    Abstract: This study aimed to investigate the role and mechanism of POU6F2-AS2 in the development of gastric cancer. POU6F2-AS2 expression was considerably higher in clinical stomach adenocarcinoma (STAD) tissues and gastric cancer cell lines (MKN-28 and MGC-803) ... ...

    Abstract This study aimed to investigate the role and mechanism of POU6F2-AS2 in the development of gastric cancer. POU6F2-AS2 expression was considerably higher in clinical stomach adenocarcinoma (STAD) tissues and gastric cancer cell lines (MKN-28 and MGC-803) than in neighbouring normal tissues and gastric mucosa epithelial cells (GES-1). POU6F2-AS2 overexpression resulted in a low overall survival probability, progression-free survival probability and post progression survival probability, as well as increased cell viability, migration and invasion of gastric cancer cells, thereby inhibiting apoptosis. Based on RNA pull-down, cycloheximide and MG132 incubation experiments, POU6F2-AS2 promoted SKP2 by stabilizing NONO expression. In addition,
    MeSH term(s) Humans ; MicroRNAs/genetics ; RNA, Long Noncoding/genetics ; Paclitaxel/pharmacology ; Paclitaxel/therapeutic use ; Stomach Neoplasms/drug therapy ; Stomach Neoplasms/genetics ; Cell Line, Tumor ; Adenocarcinoma/drug therapy ; Adenocarcinoma/genetics ; Phenotype ; Cell Proliferation/genetics ; Gene Expression Regulation, Neoplastic ; POU Domain Factors/genetics ; POU Domain Factors/metabolism
    Chemical Substances MicroRNAs ; RNA, Long Noncoding ; Paclitaxel (P88XT4IS4D) ; POU6F2 protein, human ; POU Domain Factors
    Language English
    Publishing date 2023-02-16
    Publishing country England
    Document type Journal Article
    ZDB-ID 1036294-0
    ISSN 1973-9478 ; 1120-009X
    ISSN (online) 1973-9478
    ISSN 1120-009X
    DOI 10.1080/1120009X.2023.2177807
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2701: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
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    Zs.MO 387: Show issues

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  8. Article ; Online: Photo-Reactivity of dissolved black carbon unveiled by combination of optical spectroscopy and FT-ICR MS analysis: Effects of pyrolysis temperature.

    Li, Liangyu / Cheng, Wan / Xie, Xiaoyun / Zhao, Ranran / Wang, Yaodong / Wang, Zhaowei

    Water research

    2024  Volume 251, Page(s) 121138

    Abstract: Dissolved black carbon (DBC) has high photoactivity, which plays an important role in contaminants photodegradation. However, it is unclear how pyrolysis temperatures would affect the composition and photo-reactivity of DBC at the molecular level. Herein, ...

    Abstract Dissolved black carbon (DBC) has high photoactivity, which plays an important role in contaminants photodegradation. However, it is unclear how pyrolysis temperatures would affect the composition and photo-reactivity of DBC at the molecular level. Herein, we combined complementary techniques to study the characteristics of DBC pyrolyzed at 200 - 500 ℃, as well as the photoproduction of reactive species and the photodegradation of tetracycline (TC). Bulk composition characterization found that condensed aromatic carbonyl compounds (ConAC) with narrow molecular weights in DBC experienced an increase from 200 to 500 °C, which enhanced the photoproduction of
    MeSH term(s) Temperature ; Pyrolysis ; Photolysis ; Spectrum Analysis ; Soot/analysis ; Soot/chemistry ; Anti-Bacterial Agents ; Tetracycline ; Carbon
    Chemical Substances Soot ; Anti-Bacterial Agents ; Tetracycline (F8VB5M810T) ; Carbon (7440-44-0)
    Language English
    Publishing date 2024-01-15
    Publishing country England
    Document type Journal Article
    ZDB-ID 202613-2
    ISSN 1879-2448 ; 0043-1354
    ISSN (online) 1879-2448
    ISSN 0043-1354
    DOI 10.1016/j.watres.2024.121138
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    In stock of ZB MED Bonn / Germany

    Z 78/260: Show issues
    Z 3381: Show issues

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  9. Article ; Online: Herpes zoster-induced acute urinary retention, limb paresis, and constipation in two immunocompetent patients.

    Lu, XiaoYun / Cheng, Fang / Xiao, FengLi

    Clinical autonomic research : official journal of the Clinical Autonomic Research Society

    2022  Volume 32, Issue 1, Page(s) 77–80

    MeSH term(s) Constipation/etiology ; Female ; Herpes Zoster/complications ; Herpes Zoster/diagnosis ; Humans ; Male ; Paresis/etiology ; Urinary Retention/etiology
    Language English
    Publishing date 2022-01-04
    Publishing country Germany
    Document type Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 1080007-4
    ISSN 1619-1560 ; 0959-9851
    ISSN (online) 1619-1560
    ISSN 0959-9851
    DOI 10.1007/s10286-021-00846-x
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3270: Show issues Location:
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  10. Article: Erratum: CircNT5E promotes the proliferation and migration of bladder cancer via sponging miR-502-5p: Erratum.

    Yang, Jinhui / Liu, Xiaoyun / Dai, Guangcheng / Qu, Lanying / Tan, Bo / Zhu, Bo / Qi, Fuming / Gai, Xinyu / Cheng, Bo

    Journal of Cancer

    2024  Volume 15, Issue 10, Page(s) 3152–3153

    Abstract: This corrects the article DOI: 10.7150/jca.53385.]. ...

    Abstract [This corrects the article DOI: 10.7150/jca.53385.].
    Language English
    Publishing date 2024-04-11
    Publishing country Australia
    Document type Published Erratum
    ZDB-ID 2573318-7
    ISSN 1837-9664
    ISSN 1837-9664
    DOI 10.7150/jca.93985
    Database MEDical Literature Analysis and Retrieval System OnLINE

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