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  1. AU=Cohen Irun R
  2. AU="Mo, Zhao-Hui"
  3. AU="Bahar, Fahmi"
  4. AU="Stambouli, Sarra"
  5. AU="Held, Susanne"
  6. AU="Warit, Saradee"
  7. AU="Songco, Annabel" AU="Songco, Annabel"
  8. AU="Nezbeda, Ivo"
  9. AU="Bair, Henry"
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  1. Artikel ; Online: Evolution is driven by natural autoencoding: reframing species, interaction codes, cooperation and sexual reproduction.

    Cohen, Irun R / Marron, Assaf

    Proceedings. Biological sciences

    2023  Band 290, Heft 1994, Seite(n) 20222409

    Abstract: The continuity of life and its evolution, we proposed, emerge from an interactive group process manifested in networks of interaction. We term this ... ...

    Abstract The continuity of life and its evolution, we proposed, emerge from an interactive group process manifested in networks of interaction. We term this process
    Mesh-Begriff(e) Algorithms ; Recognition, Psychology ; Reproduction
    Sprache Englisch
    Erscheinungsdatum 2023-03-01
    Erscheinungsland England
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 209242-6
    ISSN 1471-2954 ; 0080-4649 ; 0962-8452 ; 0950-1193
    ISSN (online) 1471-2954
    ISSN 0080-4649 ; 0962-8452 ; 0950-1193
    DOI 10.1098/rspb.2022.2409
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Buch: Tending Adam's garden

    Cohen, Irun R.

    evolving the cognitive immune self

    2000  

    Verfasserangabe Irun R. Cohen
    Sprache Englisch
    Umfang XX, 266 S. : graph. Darst.
    Verlag Academic Press
    Erscheinungsort San Diego u.a.
    Erscheinungsland Vereinigte Staaten
    Dokumenttyp Buch
    HBZ-ID HT011231792
    ISBN 0-12-178355-3 ; 978-0-12-178355-6
    Datenquelle Katalog ZB MED Medizin, Gesundheit

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  3. Artikel ; Online: Avraham Ben-Nun-Pioneer, fighter, friend.

    Cohen, Irun R / Wekerle, Hartmut

    European journal of immunology

    2019  Band 49, Heft 4, Seite(n) 521–522

    Sprache Englisch
    Erscheinungsdatum 2019-03-19
    Erscheinungsland Germany
    Dokumenttyp Journal Article
    ZDB-ID 120108-6
    ISSN 1521-4141 ; 0014-2980
    ISSN (online) 1521-4141
    ISSN 0014-2980
    DOI 10.1002/eji.201970046
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Buch: Autoimmune disease models

    Cohen, Irun R.

    a guidebook

    1994  

    Verfasserangabe ed. by Irun R. Cohen
    Schlagwörter Autoimmune Diseases ; Disease Models, Animal ; Mice ; Rats ; Autoaggressionskrankheit ; Tiermodell
    Schlagwörter Autoantikörperkrankheit ; Autoimmunkrankheit ; Autoimmunopathie ; Autoimmunerkrankung
    Sprache Englisch
    Umfang XVIII, 329 S. : Ill.
    Verlag Acad. Press
    Erscheinungsort San Diego u.a.
    Erscheinungsland Vereinigte Staaten
    Dokumenttyp Buch
    HBZ-ID HT006541403
    ISBN 0-12-178330-8 ; 978-0-12-178330-3
    Datenquelle Katalog ZB MED Medizin, Gesundheit

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  5. Artikel: Updating Darwin: Information and entropy drive the evolution of life.

    Cohen, Irun R

    F1000Research

    2016  Band 5, Seite(n) 2808

    Abstract: The evolution of species, according to Darwin, is driven by struggle - by competition between variant autonomous individuals ... ...

    Abstract The evolution of species, according to Darwin, is driven by struggle - by competition between variant autonomous individuals for
    Sprache Englisch
    Erscheinungsdatum 2016-12-01
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 2699932-8
    ISSN 2046-1402
    ISSN 2046-1402
    DOI 10.12688/f1000research.10289.1
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel ; Online: The evolution of universal adaptations of life is driven by universal properties of matter: energy, entropy, and interaction.

    Cohen, Irun R / Marron, Assaf

    F1000Research

    2020  Band 9, Seite(n) 626

    Abstract: The evolution of multicellular eukaryotes expresses two sorts of adaptations: local adaptations like fur or feathers, which characterize species in particular environments, and universal adaptations like microbiomes or sexual reproduction, which ... ...

    Abstract The evolution of multicellular eukaryotes expresses two sorts of adaptations: local adaptations like fur or feathers, which characterize species in particular environments, and universal adaptations like microbiomes or sexual reproduction, which characterize most multicellulars in any environment. We reason that the mechanisms driving the universal adaptations of multicellulars should themselves be universal, and propose a mechanism based on properties of matter and systems:
    Mesh-Begriff(e) Adaptation, Biological ; Animals ; Entropy ; Humans ; Metabolic Networks and Pathways ; Microbiota ; Phenotype ; Reproduction
    Sprache Englisch
    Erscheinungsdatum 2020-06-18
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 2699932-8
    ISSN 2046-1402 ; 2046-1402
    ISSN (online) 2046-1402
    ISSN 2046-1402
    DOI 10.12688/f1000research.24447.3
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Buch: Perspectives on autoimmunity

    Cohen, Irun R.

    1988  

    Verfasserangabe ed. Irun R. Cohen
    Schlagwörter Autoantibodies ; Autoimmune Diseases ; Autoaggressionskrankheit
    Schlagwörter Autoantikörperkrankheit ; Autoimmunkrankheit ; Autoimmunopathie ; Autoimmunerkrankung
    Umfang 225 S. : graph. Darst.
    Verlag CRC Pr
    Erscheinungsort Boca Raton, Fla
    Erscheinungsland Vereinigte Staaten
    Dokumenttyp Buch
    HBZ-ID HT003335522
    ISBN 0-8493-6431-0 ; 978-0-8493-6431-0
    Datenquelle Katalog ZB MED Medizin, Gesundheit

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  8. Artikel ; Online: The evolution of universal adaptations of life is driven by universal properties of matter

    Irun R. Cohen / Assaf Marron

    F1000Research, Vol

    energy, entropy, and interaction [version 2; peer review: 2 approved]

    2020  Band 9

    Abstract: The evolution of multicellular eukaryotes expresses two sorts of adaptations: local adaptations like fur or feathers, which characterize species in particular environments, and universal adaptations like microbiomes or sexual reproduction, which ... ...

    Abstract The evolution of multicellular eukaryotes expresses two sorts of adaptations: local adaptations like fur or feathers, which characterize species in particular environments, and universal adaptations like microbiomes or sexual reproduction, which characterize most multicellulars in any environment. We reason that the mechanisms driving the universal adaptations of multicellulars should themselves be universal, and propose a mechanism based on properties of matter and systems: energy, entropy, and interaction. Energy from the sun, earth and beyond creates new arrangements and interactions. Metabolic networks channel some of this energy to form cooperating, interactive arrangements. Entropy, used here as a term for all forces that dismantle ordered structures (rather than as a physical quantity), acts as a selective force. Entropy selects for arrangements that resist it long enough to replicate, and dismantles those that do not. Interactions, energy-charged and dynamic, restrain entropy and enable survival and propagation of integrated living systems. This fosters survival-of-the-fitted – those entities that resist entropic destruction – and not only of the fittest – the entities with the greatest reproductive success. The “unit” of evolution is not a discrete entity, such as a gene, individual, or species; what evolves are collections of related interactions at multiple scales. Survival-of-the-fitted explains universal adaptations, including resident microbiomes, sexual reproduction, continuous diversification, programmed turnover, seemingly wasteful phenotypes, altruism, co-evolving environmental niches, and advancing complexity. Indeed survival-of-the-fittest may be a particular case of the survival-of-the-fitted mechanism, promoting local adaptations that express reproductive advantages in addition to resisting entropy. Survival-of-the-fitted accounts for phenomena that have been attributed to neutral evolution: in the face of entropy, there is no neutrality; all variations are challenged by ubiquitous energy ...
    Schlagwörter Medicine ; R ; Science ; Q
    Thema/Rubrik (Code) 612
    Sprache Englisch
    Erscheinungsdatum 2020-07-01T00:00:00Z
    Verlag F1000 Research Ltd
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  9. Artikel ; Online: The evolution of universal adaptations of life is driven by universal properties of matter

    Irun R. Cohen / Assaf Marron

    F1000Research, Vol

    energy, entropy, and interaction [version 3; peer review: 3 approved]

    2020  Band 9

    Abstract: The evolution of multicellular eukaryotes expresses two sorts of adaptations: local adaptations like fur or feathers, which characterize species in particular environments, and universal adaptations like microbiomes or sexual reproduction, which ... ...

    Abstract The evolution of multicellular eukaryotes expresses two sorts of adaptations: local adaptations like fur or feathers, which characterize species in particular environments, and universal adaptations like microbiomes or sexual reproduction, which characterize most multicellulars in any environment. We reason that the mechanisms driving the universal adaptations of multicellulars should themselves be universal, and propose a mechanism based on properties of matter and systems: energy, entropy, and interaction. Energy from the sun, earth and beyond creates new arrangements and interactions. Metabolic networks channel some of this energy to form cooperating, interactive arrangements. Entropy, used here as a term for all forces that dismantle ordered structures (rather than as a physical quantity), acts as a selective force. Entropy selects for arrangements that resist it long enough to replicate, and dismantles those that do not. Interactions, energy-charged and dynamic, restrain entropy and enable survival and propagation of integrated living systems. This fosters survival-of-the-fitted – those entities that resist entropic destruction – and not only of the fittest – the entities with the greatest reproductive success. The “unit” of evolution is not a discrete entity, such as a gene, individual, or species; what evolves are collections of related interactions at multiple scales. Survival-of-the-fitted explains universal adaptations, including resident microbiomes, sexual reproduction, continuous diversification, programmed turnover, seemingly wasteful phenotypes, altruism, co-evolving environmental niches, and advancing complexity. Indeed survival-of-the-fittest may be a particular case of the survival-of-the-fitted mechanism, promoting local adaptations that express reproductive advantages in addition to resisting entropy. Survival-of-the-fitted accounts for phenomena that have been attributed to neutral evolution: in the face of entropy, there is no neutrality; all variations are challenged by ubiquitous energy ...
    Schlagwörter Medicine ; R ; Science ; Q
    Thema/Rubrik (Code) 612
    Sprache Englisch
    Erscheinungsdatum 2020-09-01T00:00:00Z
    Verlag F1000 Research Ltd
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  10. Buch ; Online: Evolution is Driven by Natural Autoencoding

    Cohen, Irun R. / Marron, Assaf

    Reframing Species, Interaction Codes, Cooperation, and Sexual Reproduction

    2022  

    Abstract: The continuity of life and its evolution, we proposed, emerge from an interactive group process manifested in networks of interaction. We term this process \textit{survival-of-the-fitted}. Here, we reason that survival of the fitted results from a ... ...

    Abstract The continuity of life and its evolution, we proposed, emerge from an interactive group process manifested in networks of interaction. We term this process \textit{survival-of-the-fitted}. Here, we reason that survival of the fitted results from a natural computational process we term \textit{natural autoencoding}. Natural autoencoding works by retaining repeating biological interactions while non-repeatable interactions disappear. (1) We define a species by its \textit{species interaction code}, which consists of a compact description of the repeating interactions of species organisms with their external and internal environments. Species interaction codes are descriptions recorded in the biological infrastructure that enables repeating interactions. Encoding and decoding are interwoven. (2) Evolution proceeds by natural autoencoding of sustained changes in species interaction codes. DNA is only one element in natural autoencoding. (3) Natural autoencoding accounts for the paradox of genome randomization in sexual reproduction -- recombined genomes are analogous to the diversified inputs required for artificial autoencoding. The increase in entropy generated by genome randomization compensates for the decrease in entropy generated by organized life. (4) Natural autoencoding and artificial autoencoding algorithms manifest defined similarities and differences. Recognition of the importance of fittedness could well serve the future of a humanly livable biosphere.

    Comment: In version 7 we added various clarifications including to terminology, definitions, and to the reference to the second law of thermodynamics
    Schlagwörter Computer Science - Neural and Evolutionary Computing
    Thema/Rubrik (Code) 612
    Erscheinungsdatum 2022-03-22
    Erscheinungsland us
    Dokumenttyp Buch ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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