LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 101

Search options

  1. Article ; Online: [The significance of autoantibodies against nodal and paranodal proteins in autoimmune nodopathies].

    Ogata, Hidenori

    Rinsho shinkeigaku = Clinical neurology

    2023  Volume 63, Issue 11, Page(s) 715–724

    Abstract: Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is recognized as a syndrome caused by multiple pathologies. Since the 2010s, it has been clarified that autoantibodies against membranous proteins localized in the nodes of Ranvier and ... ...

    Abstract Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is recognized as a syndrome caused by multiple pathologies. Since the 2010s, it has been clarified that autoantibodies against membranous proteins localized in the nodes of Ranvier and paranodes are positive in subsets of CIDP patients, leading to proposing a new disease concept called autoimmune nodopathies, which is independent of CIDP, in the revised international CIDP guidelines. This article reviews the significance of these autoantibodies, especially anti-neurofascin 155 and anti-contactin 1 antibodies, which have been the most prevalent and achieved a higher degree of consensus.
    MeSH term(s) Humans ; Cell Adhesion Molecules ; Ranvier's Nodes/metabolism ; Ranvier's Nodes/pathology ; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating ; Autoantibodies/metabolism ; Nerve Growth Factors
    Chemical Substances Cell Adhesion Molecules ; Autoantibodies ; Nerve Growth Factors
    Language Japanese
    Publishing date 2023-10-25
    Publishing country Japan
    Document type Review ; English Abstract ; Journal Article
    ZDB-ID 604200-4
    ISSN 1882-0654 ; 0009-918X
    ISSN (online) 1882-0654
    ISSN 0009-918X
    DOI 10.5692/clinicalneurol.cn-001878
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article: [Autoantibodies in Chronic Immune-Mediated Demyelinating Polyneuropathy].

    Ogata, Hidenori

    Brain and nerve = Shinkei kenkyu no shinpo

    2023  Volume 75, Issue 7, Page(s) 813–819

    Abstract: Autoantibodies against nodal and paranodal proteins, such as neurofascin 140/186, neurofascin 155, contactin 1, and contactin-associated protein 1, have been identified in subsets of patients with chronic inflammatory demyelinating polyneuropathy. Their ... ...

    Abstract Autoantibodies against nodal and paranodal proteins, such as neurofascin 140/186, neurofascin 155, contactin 1, and contactin-associated protein 1, have been identified in subsets of patients with chronic inflammatory demyelinating polyneuropathy. Their distinctive characteristics including poor response to immunoglobulin led to the establishment of a new disease entity called "autoimmune nodopathies." IgM monoclonal antibodies against myelin-associated glycoproteins cause intractable sensory-dominant demyelinating polyneuropathy. IgM anti-GM1 and IgG anti-LM1 antibodies are associated with multifocal motor neuropathy and chronic inflammatory demyelinating polyneuropathy, respectively. Monoclonal IgM against disialosyl ganglioside epitopes induces chronic ataxic neuropathy with ophthalmoplegia and cold agglutinin.
    MeSH term(s) Humans ; Autoantibodies ; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating ; Antibodies, Monoclonal ; Immunoglobulin G ; Immunoglobulin M ; Polyneuropathies
    Chemical Substances Autoantibodies ; Antibodies, Monoclonal ; Immunoglobulin G ; Immunoglobulin M
    Language Japanese
    Publishing date 2023-07-11
    Publishing country Japan
    Document type English Abstract ; Journal Article
    ZDB-ID 390389-8
    ISSN 1344-8129 ; 1881-6096 ; 0006-8969
    ISSN (online) 1344-8129
    ISSN 1881-6096 ; 0006-8969
    DOI 10.11477/mf.1416202426
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article ; Online: Complete genome sequences of

    Okuhama, Shinnosuke / Takahashi, Hidenori / Nakayama, Yasunori / Ogata, Yusuke / Suda, Wataru

    Microbiology resource announcements

    2023  Volume 13, Issue 1, Page(s) e0078423

    Abstract: Here, we report the complete genome sequence of ... ...

    Abstract Here, we report the complete genome sequence of the
    Language English
    Publishing date 2023-12-15
    Publishing country United States
    Document type Journal Article
    ISSN 2576-098X
    ISSN (online) 2576-098X
    DOI 10.1128/mra.00784-23
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article ; Online: Pediatric Anti-Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease With Combined Central and Peripheral Demyelination.

    Horiguchi, Ayumi / Kikuchi, Kenjiro / Horita, Haruhito / Ogata, Hidenori / Hamano, Shin-Ichiro

    Pediatric neurology

    2023  Volume 152, Page(s) 30–33

    MeSH term(s) Humans ; Child ; Myelin-Oligodendrocyte Glycoprotein ; Autoantigens ; Demyelinating Diseases/diagnostic imaging ; Oligodendroglia ; Autoantibodies ; Optic Neuritis
    Chemical Substances Myelin-Oligodendrocyte Glycoprotein ; Autoantigens ; Autoantibodies
    Language English
    Publishing date 2023-12-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 639164-3
    ISSN 1873-5150 ; 0887-8994
    ISSN (online) 1873-5150
    ISSN 0887-8994
    DOI 10.1016/j.pediatrneurol.2023.12.011
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Article: [Concepts and epidemiology of combined central and peripheral demyelination].

    Ogata, Hidenori

    Nihon rinsho. Japanese journal of clinical medicine

    2015  Volume 73 Suppl 7, Page(s) 341–346

    MeSH term(s) Adult ; Demyelinating Diseases/diagnosis ; Demyelinating Diseases/epidemiology ; Diagnosis, Differential ; Female ; Humans ; Japan/epidemiology ; Male ; Multiple Sclerosis/diagnosis ; Peripheral Nervous System Diseases/diagnosis ; Peripheral Nervous System Diseases/epidemiology ; Time Factors
    Language Japanese
    Publishing date 2015-09
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 390903-7
    ISSN 0047-1852
    ISSN 0047-1852
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  6. Article ; Online: Editorial

    Tomomichi Ogata / Takanori Horii / Hidenori Aiki / Yu-Lin K. Chang / Iskhaq Iskandar / Yukio Masumoto

    Frontiers in Climate, Vol

    Multi-scale air-sea variability and its application in Indo-Pacific regions

    2023  Volume 5

    Keywords El Niño-Southern Oscillation ; Indian Ocean Dipole (IOD) ; Indo-Pacific region ; tropical pacific and Indian Ocean ; tropical cyclone (TC) ; satellite observation ; Environmental sciences ; GE1-350
    Language English
    Publishing date 2023-07-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  7. Article ; Online: Prenatal test cohort of a modified rat comparative thyroid assay adding brain thyroid hormone measurements and histology but lowering group size appears able to detect disruption by sodium phenobarbital.

    Minami, Kenta / Sato, Akira / Tomiyama, Naruto / Ogata, Keiko / Kosaka, Tadashi / Hojo, Hitoshi / Takahashi, Naofumi / Suto, Hidenori / Aoyama, Hiroaki / Yamada, Tomoya

    Current research in toxicology

    2024  Volume 6, Page(s) 100168

    Abstract: The Comparative Thyroid Assay (CTA, USEPA) is a screening test for thyroid hormone (TH) disruption in peripheral blood of dams and offspring. Recently, we began investigating feasible improvements to the CTA by adding examination of offspring brain TH ... ...

    Abstract The Comparative Thyroid Assay (CTA, USEPA) is a screening test for thyroid hormone (TH) disruption in peripheral blood of dams and offspring. Recently, we began investigating feasible improvements to the CTA by adding examination of offspring brain TH concentrations and brain histopathology. In addition, we hypothesize that the number of animals required could be reduced by 50 % while still maintaining sensitivity to characterize treatment related changes in THs. Previously, we showed that the prenatal test cohort of the modified CTA could detect 1000 ppm sodium phenobarbital (NaPB)-induced suppression of brain T3 (by 9 %) and T4 (by 33 %) with no significant changes in serum T3 and T4 (less than 8 %). In the current study we expanded the dose response in a prenatal test cohort. Pregnant SD rats (N = 10/group) were exposed to 0, 1000 or 1500 ppm NaPB in the diet from gestational days (GD) 6 to GD20. Serum THs concentrations in GD20 dams together with serum/brain THs concentrations and brain histopathology in the GD20 fetuses were examined. NaPB dose-dependently suppressed serum T3 (up to -26 %) and T4 (up to -44 %) in dams, with suppression of T3 in serum (up to -26 %) and brain (up to -18 %) and T4 in serum (up to -26 %) and brain (up to -29 %) of fetuses but without clear dose dependency. There were no remarkable findings that deviated significantly from controls in GD20 fetal brain by qualitative histopathology. Overall, the present study suggests that the prenatal test cohort of this modified CTA is able to detect the expected fetal TH disruptions by prenatal exposure to NaPB, while also reducing the number of animals used by 50 %, consistent with the results of our previous study. These findings add to the suggestion that lowering group sizes and adding endpoints may be a useful alternative to the original CTA design.
    Language English
    Publishing date 2024-04-18
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2666-027X
    ISSN (online) 2666-027X
    DOI 10.1016/j.crtox.2024.100168
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  8. Article ; Online: Teaching Video NeuroImage: Reversible Parkinsonism Caused by Lumboperitoneal Shunt Overdrainage.

    Takeuchi, Hajime / Masaki, Katsuhisa / Ogata, Hidenori / Nagata, Satoshi / Shimogawa, Takafumi / Yamasaki, Ryo / Isobe, Noriko

    Neurology

    2022  Volume 99, Issue 11, Page(s) 486–488

    MeSH term(s) Cerebrospinal Fluid Shunts/adverse effects ; Humans ; Hydrocephalus/surgery ; Parkinsonian Disorders/diagnostic imaging ; Parkinsonian Disorders/etiology ; Ventriculoperitoneal Shunt/adverse effects
    Language English
    Publishing date 2022-07-08
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 207147-2
    ISSN 1526-632X ; 0028-3878
    ISSN (online) 1526-632X
    ISSN 0028-3878
    DOI 10.1212/WNL.0000000000200994
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  9. Article ; Online: The vertical structure of annual wave energy flux in the tropical Indian Ocean

    Zimeng Li / Hidenori Aiki / Motoki Nagura / Tomomichi Ogata

    Progress in Earth and Planetary Science, Vol 8, Iss 1, Pp 1-

    2021  Volume 19

    Abstract: Abstract A recently developed energy flux diagnosis scheme, which incorporates a smooth connection between the tropical and subtropical zones, is used in the present study to investigate vertically propagating waves in the tropical Indian Ocean (IO) ... ...

    Abstract Abstract A recently developed energy flux diagnosis scheme, which incorporates a smooth connection between the tropical and subtropical zones, is used in the present study to investigate vertically propagating waves in the tropical Indian Ocean (IO) based on the result of a linear, continuously stratified ocean model driven by climatological wind forcing. This extended diagnosis reveals deep-reaching eastward energy fluxes at the equator which develop four times per year and are associated with equatorial Kelvin waves (KWs) generated by semiannual winds. The authors find that the downward transfer of wave energy is particularly deep in the southern Bay of Bengal (SBoB). This downward flux is attributed to off-equatorial Rossby waves and appears four times per year, maximizing its amplitude during November–December. Southwesterly winds in the Arabian Sea intensify eastward energy flux of KWs at mid-depth, which maximizes in amplitude in August. This is contrastive to KW energy flux at the surface which peaks in May. These mid-depth equatorial KW packets subsequently arrive at the eastern boundary of the IO and are diffracted poleward to produce downward energy flux in November and December detected in the SBoB.
    Keywords Indian Ocean ; Kelvin wave ; Rossby wave ; Seasonal variation ; Vertical structure ; Wave energy ; Geography. Anthropology. Recreation ; G ; Geology ; QE1-996.5
    Subject code 551
    Language English
    Publishing date 2021-07-01T00:00:00Z
    Publisher SpringerOpen
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  10. Article ; Online: Randomization and Constraint of Molecular Alignment and Orientation

    Masahito Oh-e / Hidenori Ogata / Fumito Araoka

    ACS Omega, Vol 4, Iss 1, Pp 39-

    Temperature-Dependent Anisotropy and Phase Transition in Vapor-Deposited Thin Films of an Organic Cross-Shaped Molecule

    2019  Volume 47

    Keywords Chemistry ; QD1-999
    Language English
    Publishing date 2019-01-01T00:00:00Z
    Publisher American Chemical Society
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

To top