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  1. AU=Shimizu Kazuki
  2. AU=Pell Robert AU=Pell Robert
  3. AU="Aguiar, Liza"
  4. AU="Bahls, Christine"
  5. AU="Dongho Lee"
  6. AU=Houser Steven R.
  7. AU="Morgom M.M."
  8. AU="Jordana-Comajuncosa, Rosa"
  9. AU="Kaushansky, Alexis"
  10. AU="Bhatjiwale, Mohinish"
  11. AU="Velu, Chinavenmeni S"
  12. AU=Trayanova Natalia A
  13. AU=Jimeno-Gonzlez Silvia
  14. AU=Bussolino F
  15. AU="Almulla, Hanan"
  16. AU="Chen, Wenmei"
  17. AU=Zeng Weiqing

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  1. Artikel ; Online: A SWOT Analysis of the Guidelines on Prevention of HIV/AIDS in Japan in the Context of COVID-19

    Kazuki Shimizu

    Infectious Disease Reports, Vol 13, Iss 87, Pp 949-

    2021  Band 956

    Abstract: In January 2018, the Minister of Health, Labour and Welfare, Japan, released an amended Guideline on the Prevention of Specified Infectious Diseases on Acquired Immunodeficiency Syndrome (AIDS) to propose measures to control the human immunodeficiency ... ...

    Abstract In January 2018, the Minister of Health, Labour and Welfare, Japan, released an amended Guideline on the Prevention of Specified Infectious Diseases on Acquired Immunodeficiency Syndrome (AIDS) to propose measures to control the human immunodeficiency virus (HIV)/AIDS. Content analysis was performed to examine the strengths, weaknesses, opportunities, and threats of the guidelines in the context of the ongoing COVID-19 pandemic, thus aiming to promote discussions on the guideline itself and the national HIV/AIDS strategy in Japan in the years ahead. The strengths included the incorporation of the latest scientific advancements, clarification of high-risk populations, an alignment with measures against sexually transmitted diseases (STDs), and willingness towards international cooperation in the Asia-Pacific region. The weaknesses that were exposed included a lack of explicit targets for controlling and containing HIV/AIDS, insufficient descriptions about pre-exposure prophylaxis (PrEP), and aggregated discussions on HIV/AIDS among foreign residents. Although several opportunities for re-energizing the discussions around HIV/AIDS were recognized, insufficient political will and funding, along with the emergence of the ongoing COVID-19 pandemic, could operate as threats. Addressing barriers that were recognized before 2019 and exposed due to the COVID-19 pandemic, and tackling underlying health inequalities through the concept of social determinants of health will be critical.
    Schlagwörter HIV/AIDS ; health policy ; policy analysis ; prevention ; testing ; antiretroviral therapy ; Other systems of medicine ; RZ201-999
    Thema/Rubrik (Code) 360
    Sprache Englisch
    Erscheinungsdatum 2021-11-01T00:00:00Z
    Verlag MDPI AG
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  2. Artikel: A SWOT Analysis of the Guidelines on Prevention of HIV/AIDS in Japan in the Context of COVID-19.

    Shimizu, Kazuki

    Infectious disease reports

    2021  Band 13, Heft 4, Seite(n) 949–956

    Abstract: In January 2018, the Minister of Health, Labour and Welfare, Japan, released an amended Guideline on the Prevention of Specified Infectious Diseases on Acquired Immunodeficiency Syndrome (AIDS) to propose measures to control the human immunodeficiency ... ...

    Abstract In January 2018, the Minister of Health, Labour and Welfare, Japan, released an amended Guideline on the Prevention of Specified Infectious Diseases on Acquired Immunodeficiency Syndrome (AIDS) to propose measures to control the human immunodeficiency virus (HIV)/AIDS. Content analysis was performed to examine the strengths, weaknesses, opportunities, and threats of the guidelines in the context of the ongoing COVID-19 pandemic, thus aiming to promote discussions on the guideline itself and the national HIV/AIDS strategy in Japan in the years ahead. The strengths included the incorporation of the latest scientific advancements, clarification of high-risk populations, an alignment with measures against sexually transmitted diseases (STDs), and willingness towards international cooperation in the Asia-Pacific region. The weaknesses that were exposed included a lack of explicit targets for controlling and containing HIV/AIDS, insufficient descriptions about pre-exposure prophylaxis (PrEP), and aggregated discussions on HIV/AIDS among foreign residents. Although several opportunities for re-energizing the discussions around HIV/AIDS were recognized, insufficient political will and funding, along with the emergence of the ongoing COVID-19 pandemic, could operate as threats. Addressing barriers that were recognized before 2019 and exposed due to the COVID-19 pandemic, and tackling underlying health inequalities through the concept of social determinants of health will be critical.
    Sprache Englisch
    Erscheinungsdatum 2021-11-05
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ISSN 2036-7430
    ISSN 2036-7430
    DOI 10.3390/idr13040087
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: 2019-nCoV, fake news, and racism.

    Shimizu, Kazuki

    Lancet (London, England)

    2020  Band 395, Heft 10225, Seite(n) 685–686

    Mesh-Begriff(e) COVID-19 ; China/epidemiology ; Coronavirus Infections/epidemiology ; Disease Outbreaks ; Humans ; Japan/epidemiology ; Pneumonia, Viral/epidemiology ; Racism ; Social Media
    Schlagwörter covid19
    Sprache Englisch
    Erscheinungsdatum 2020-02-11
    Erscheinungsland England
    Dokumenttyp Letter
    ZDB-ID 3306-6
    ISSN 1474-547X ; 0023-7507 ; 0140-6736
    ISSN (online) 1474-547X
    ISSN 0023-7507 ; 0140-6736
    DOI 10.1016/S0140-6736(20)30357-3
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel ; Online: Long-term effectiveness and cost-effectiveness of guided internet-based cognitive behavioral therapy for obsessive-compulsive disorder: 24-month follow-up.

    Matsumoto, Kazuki / Hamatani, Sayo / Shimizu, Eiji

    Internet interventions

    2024  Band 35, Seite(n) 100725

    Abstract: This study investigated the long-term effectiveness and cost-effectiveness of guided internet-based cognitive behavioral therapy (ICBT) for obsessive-compulsive disorder (OCD). Twenty-five patients with OCD who had undergone guided ICBT in a randomized ... ...

    Abstract This study investigated the long-term effectiveness and cost-effectiveness of guided internet-based cognitive behavioral therapy (ICBT) for obsessive-compulsive disorder (OCD). Twenty-five patients with OCD who had undergone guided ICBT in a randomized controlled trial or a single-arm trial were followed up for 6, 12, and 24 months. Missing data were imputed using the mice package in R, and a one-way analysis of variance with repeated measures was performed. The total Yale-Brown Obsessive-Compulsive Scale (Y-BOCS) score significantly decreased from baseline to all endpoints
    Sprache Englisch
    Erscheinungsdatum 2024-02-08
    Erscheinungsland Netherlands
    Dokumenttyp Journal Article
    ZDB-ID 2764252-5
    ISSN 2214-7829 ; 2214-7829
    ISSN (online) 2214-7829
    ISSN 2214-7829
    DOI 10.1016/j.invent.2024.100725
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: An Extremely Delayed Onset of Frey Syndrome: A Case Report and Literature Review.

    Kobayashi, Yuya / Kasuga, Kazuki / Shimizu, Yusaku / Sekijima, Yoshiki

    Internal medicine (Tokyo, Japan)

    2024  

    Abstract: We report the case of an 80-year-old man with Frey syndrome that developed 30 years postoperatively, which is an exceptionally long period before its occurrence. Sweating and flushing occurred on only the side of his face where the surgery was performed, ...

    Abstract We report the case of an 80-year-old man with Frey syndrome that developed 30 years postoperatively, which is an exceptionally long period before its occurrence. Sweating and flushing occurred on only the side of his face where the surgery was performed, and he had no other causative abnormalities. Following treatment with botulinum toxin, the patient's symptoms resolved. Extremely early- and late-onset cases do not fit the conventional paradigm of this pathology. Various surgical methods to prevent this syndrome have been explored, but complete prevention has not yet been achieved. These findings suggest that the underlying pathophysiology of Frey's syndrome may be more complex than previously recognized.
    Sprache Englisch
    Erscheinungsdatum 2024-02-26
    Erscheinungsland Japan
    Dokumenttyp Journal Article
    ZDB-ID 32371-8
    ISSN 1349-7235 ; 0021-5120 ; 0918-2918
    ISSN (online) 1349-7235
    ISSN 0021-5120 ; 0918-2918
    DOI 10.2169/internalmedicine.3094-23
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel ; Online: Defamation Against Healthcare Workers During COVID-19 Pandemic.

    Shimizu, Kazuki / Lin, Leesa

    International journal of health policy and management

    2022  Band 11, Heft 5, Seite(n) 720–721

    Mesh-Begriff(e) COVID-19 ; Defamation ; Health Personnel ; Humans ; Influenza A Virus, H1N1 Subtype ; Pandemics
    Schlagwörter covid19
    Sprache Englisch
    Erscheinungsdatum 2022-05-01
    Erscheinungsland Iran
    Dokumenttyp Letter
    ZDB-ID 2724317-5
    ISSN 2322-5939 ; 2322-5939
    ISSN (online) 2322-5939
    ISSN 2322-5939
    DOI 10.34172/ijhpm.2020.184
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel ; Online: Defamation Against Healthcare Workers During COVID-19 Pandemic

    Kazuki Shimizu / Leesa Lin

    International Journal of Health Policy and Management, Vol 11, Iss 5, Pp 720-

    2022  Band 721

    Schlagwörter covid-19 ; pandemic ; discrimination ; healthcare workers ; panic ; media ; Public aspects of medicine ; RA1-1270
    Sprache Englisch
    Erscheinungsdatum 2022-05-01T00:00:00Z
    Verlag Kerman University of Medical Sciences
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  8. Artikel ; Online: Comparative analysis of isothiocyanates in eight cruciferous vegetables and evaluation of the hepatoprotective effects of 4-(methylsulfinyl)-3-butenyl isothiocyanate (sulforaphene) from daikon radish (

    Yamaguchi, Yusuke / Sugiki, Mikio / Shimizu, Motomi / Ogawa, Kazuki / Kumagai, Hitomi

    Food & function

    2024  Band 15, Heft 9, Seite(n) 4894–4904

    Abstract: The contributions of cruciferous vegetables to human health are widely recognised, particularly at the molecular level, where their isothiocyanates play a significant role. However, compared to the well-studied isothiocyanate 4-(methylsulfinyl)butyl ... ...

    Abstract The contributions of cruciferous vegetables to human health are widely recognised, particularly at the molecular level, where their isothiocyanates play a significant role. However, compared to the well-studied isothiocyanate 4-(methylsulfinyl)butyl isothiocyanate (sulforaphane) produced from broccoli sprouts, less is known about the pharmacological effects of other isothiocyanates and the stage of vegetables preferable to obtain their benefits. We analysed the quantity and quality of isothiocyanates produced in both the sprouts and mature stages of eight cruciferous vegetables using gas chromatography-mass spectrometry (GC-MS). Additionally, we investigated the hepatoprotective effects of isothiocyanates in a mouse model of acute hepatitis induced by carbon tetrachloride (CCl
    Mesh-Begriff(e) Isothiocyanates/pharmacology ; Animals ; Mice ; Raphanus/chemistry ; Male ; Vegetables/chemistry ; Rats ; Liver/drug effects ; Liver/metabolism ; Plant Extracts/pharmacology ; Plant Extracts/chemistry ; Sulfoxides ; Chemical and Drug Induced Liver Injury/prevention & control ; Protective Agents/pharmacology ; Protective Agents/chemistry ; Brassica/chemistry ; Humans ; Rats, Sprague-Dawley ; Brassicaceae/chemistry
    Chemische Substanzen Isothiocyanates ; Plant Extracts ; Sulfoxides ; Protective Agents ; sulforaphane (GA49J4310U) ; sulphoraphene (NCO9MC39IO)
    Sprache Englisch
    Erscheinungsdatum 2024-05-07
    Erscheinungsland England
    Dokumenttyp Journal Article ; Comparative Study
    ZDB-ID 2612033-1
    ISSN 2042-650X ; 2042-6496
    ISSN (online) 2042-650X
    ISSN 2042-6496
    DOI 10.1039/d4fo00133h
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  9. Artikel: Clinical decision support system using a machine learning model to assist simultaneous cardiopulmonary auscultation: Open-label randomized controlled trial.

    Hirosawa, Takanobu / Sakamoto, Tetsu / Harada, Yukinori / Tokumasu, Kazuki / Shimizu, Taro

    Digital health

    2024  Band 10, Seite(n) 20552076241233689

    Abstract: Background: The utility of a clinical decision support system using a machine learning (ML) model for simultaneous cardiac and pulmonary auscultation is unknown.: Objective: This study aimed to develop and evaluate an ML system's utility for ... ...

    Abstract Background: The utility of a clinical decision support system using a machine learning (ML) model for simultaneous cardiac and pulmonary auscultation is unknown.
    Objective: This study aimed to develop and evaluate an ML system's utility for cardiopulmonary auscultation.
    Methods: First, we developed an ML system for cardiopulmonary auscultation, using cardiopulmonary sound files from our previous study. The technique involved pre-processing, feature extraction, and classification through several neural network layers. After integration, the output class was categorized as "normal," "abnormal," or "undetermined." Second, we evaluated the ML system with 24 junior residents in an open-label randomized controlled trial at a university hospital. Participants were randomly assigned to the ML system group (intervention) or conventional auscultation group (control). During training, participants listened to four cardiac and four pulmonary sounds, all of which were correctly classified. Then, participants classified a series of 16 simultaneous cardiopulmonary sounds. The control group auscultated the sounds using noise-cancelling headphones, while the intervention group did so by watching recommendations from the ML system.
    Results: The total scores for correctly identified normal or abnormal cardiopulmonary sounds in the intervention group were significantly higher than those in the control group (366/384 [95.3%] vs. 343/384 [89.3%],
    Conclusions: The ML-based system improved the accuracy of cardiopulmonary auscultation for junior residents. This result suggests that the system can assist early-career physicians in accurate screening.
    Sprache Englisch
    Erscheinungsdatum 2024-02-19
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 2819396-9
    ISSN 2055-2076
    ISSN 2055-2076
    DOI 10.1177/20552076241233689
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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