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Article: Complimentary address to Mr Koichi Tanaka, the winner of Nobel Prize in Chemistry 2002.

Shimizu, Akira

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

2003 Volume 792, Issue 1, Page(s) 3–4

MeSH term(s)	Chemical Phenomena ; Chemistry ; Nobel Prize
Language	English
Publishing date	2003-07-14
Publishing country	Netherlands
Document type	Address
ISSN	1570-0232
ISSN	1570-0232
DOI	10.1016/s1570-0232(03)00313-1
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Book ; Conference proceedings: Fluorescein angiography; proceedings... edited by Koichi Shimizu

Shimizu, Kōichi

1974

Title variant	Proceedings of the International Symposium on Fluorescein Angiography
Event/congress	International Symposium on Fluorescein Angiography (1972, Tokyo)
MeSH term(s)	Eye/diagnostic imaging ; Fluorescein Angiography ; Radiography
Language	English
Size	xix, 449 p., ill.
Publisher	Igaku Shoin
Publishing place	Tokyo
Document type	Book ; Conference proceedings
Database	Catalogue of the US National Library of Medicine (NLM)

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Article: Near-Infrared Transillumination for Macroscopic Functional Imaging of Animal Bodies.

Shimizu, Koichi

Biology

2023 Volume 12, Issue 11

Abstract: The classical transillumination technique has been revitalized through recent advancements in optical technology, enhancing its applicability in the realm of biomedical research. With a new perspective on near-axis scattered light, we have harnessed near- ...

Abstract	The classical transillumination technique has been revitalized through recent advancements in optical technology, enhancing its applicability in the realm of biomedical research. With a new perspective on near-axis scattered light, we have harnessed near-infrared (NIR) light to visualize intricate internal light-absorbing structures within animal bodies. By leveraging the principle of differentiation, we have extended the applicability of the Beer-Lambert law even in cases of scattering-dominant media, such as animal body tissues. This approach facilitates the visualization of dynamic physiological changes occurring within animal bodies, thereby enabling noninvasive, real-time imaging of macroscopic functionality in vivo. An important challenge inherent to transillumination imaging lies in the image blur caused by pronounced light scattering within body tissues. By extracting near-axis scattered components from the predominant diffusely scattered light, we have achieved cross-sectional imaging of animal bodies. Furthermore, we have introduced software-based techniques encompassing deconvolution using the point spread function and the application of deep learning principles to counteract the scattering effect. Finally, transillumination imaging has been elevated from two-dimensional to three-dimensional imaging. The effectiveness and applicability of these proposed techniques have been validated through comprehensive simulations and experiments involving human and animal subjects. As demonstrated through these studies, transillumination imaging coupled with emerging technologies offers a promising avenue for future biomedical applications.
Language	English
Publishing date	2023-10-24
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2661517-4
ISSN	2079-7737
ISSN	2079-7737
DOI	10.3390/biology12111362
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Article: Erratum: Optical parameters estimation in inhomogeneous turbid media using backscattered light: for transcutaneous scattering measurement of intravascular blood: erratum.

Liang, Shiyang / Miyake, Takeo / Shimizu, Koichi

Biomedical optics express

2024 Volume 15, Issue 2, Page(s) 910

Abstract: This corrects the article on p. 237 in vol. 15, PMID: 38223194.]. ...

Abstract	[This corrects the article on p. 237 in vol. 15, PMID: 38223194.].
Language	English
Publishing date	2024-01-19
Publishing country	United States
Document type	Published Erratum
ZDB-ID	2572216-5
ISSN	2156-7085
ISSN	2156-7085
DOI	10.1364/BOE.517856
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Article: Optical parameters estimation in inhomogeneous turbid media using backscattered light: for transcutaneous scattering measurement of intravascular blood.

Liang, Shiyang / Miyake, Takeo / Shimizu, Koichi

Biomedical optics express

2023 Volume 15, Issue 1, Page(s) 237–255

Abstract: In our earlier research, a technique was developed to estimate the effective attenuation coefficient of subcutaneous blood vessels from the skin surface using the spatial distribution of backscattered near-infrared (NIR) light. The scattering effect in ... ...

Abstract	In our earlier research, a technique was developed to estimate the effective attenuation coefficient of subcutaneous blood vessels from the skin surface using the spatial distribution of backscattered near-infrared (NIR) light. The scattering effect in surrounding tissues was suppressed through the application of a differential principle, provided that the
Language	English
Publishing date	2023-12-15
Publishing country	United States
Document type	Journal Article
ZDB-ID	2572216-5
ISSN	2156-7085
ISSN	2156-7085
DOI	10.1364/BOE.510245
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Article ; Online: Emerging Insights into the Role of BDNF on Health and Disease in Periphery.

Ichimura-Shimizu, Mayuko / Kurrey, Khuleshwari / Miyata, Misaki / Dezawa, Takuya / Tsuneyama, Koichi / Kojima, Masami

Biomolecules

2024 Volume 14, Issue 4

Abstract: Brain-derived neurotrophic factor (BDNF) is a growth factor that promotes the survival and growth of developing neurons. It also enhances circuit formation to synaptic transmission for mature neurons in the brain. However, reduced BDNF expression and ... ...

Abstract	Brain-derived neurotrophic factor (BDNF) is a growth factor that promotes the survival and growth of developing neurons. It also enhances circuit formation to synaptic transmission for mature neurons in the brain. However, reduced BDNF expression and single nucleotide polymorphisms (SNP) are reported to be associated with functional deficit and disease development in the brain, suggesting that BDNF is a crucial molecule for brain health. Interestingly, BDNF is also expressed in the hypothalamus in appetite and energy metabolism. Previous reports demonstrated that BDNF knockout mice exhibited overeating and obesity phenotypes remarkably. Therefore, we could raise a hypothesis that the loss of function of BDNF may be associated with metabolic syndrome and peripheral diseases. In this review, we describe our recent finding that BDNF knockout mice develop metabolic dysfunction-associated steatohepatitis and recent reports demonstrating the role of one of the BDNF receptors, TrkB-T1, in some peripheral organ functions and diseases, and would provide an insight into the role of BDNF beyond the brain.
MeSH term(s)	Brain-Derived Neurotrophic Factor/metabolism ; Brain-Derived Neurotrophic Factor/genetics ; Animals ; Humans ; Receptor, trkB/metabolism ; Receptor, trkB/genetics ; Mice ; Mice, Knockout ; Energy Metabolism/genetics ; Obesity/metabolism ; Obesity/genetics ; Polymorphism, Single Nucleotide
Chemical Substances	Brain-Derived Neurotrophic Factor ; Receptor, trkB (EC 2.7.10.1) ; BDNF protein, human (7171WSG8A2)
Language	English
Publishing date	2024-04-05
Publishing country	Switzerland
Document type	Journal Article ; Review ; Research Support, Non-U.S. Gov't
ZDB-ID	2701262-1
ISSN	2218-273X ; 2218-273X
ISSN (online)	2218-273X
ISSN	2218-273X
DOI	10.3390/biom14040444
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Article ; Online: Erratum to: Reoperation Rates of Microendoscopic Discectomy Compared With Conventional Open Lumbar Discectomy: A Large-database Study.

Masuda, Soichiro / Fukasawa, Toshiki / Takeuchi, Masato / Fujibayashi, Shunsuke / Otsuki, Bungo / Murata, Koichi / Shimizu, Takayoshi / Matsuda, Shuichi / Kawakami, Koji

Clinical orthopaedics and related research

2024 Volume 482, Issue 3, Page(s) 569

Language	English
Publishing date	2024-02-14
Publishing country	United States
Document type	Journal Article ; Published Erratum
ZDB-ID	80301-7
ISSN	1528-1132 ; 0009-921X
ISSN (online)	1528-1132
ISSN	0009-921X
DOI	10.1097/CORR.0000000000002982
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Uk I Zs.188: Show issues

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Article ; Online: Pressure Dynamics on Intervertebral Disc Cages in Transforaminal Lumbar Interbody Fusion: A Cadaver Study.

Takaki, Yoshiyama / Tanida, Shimei / Murata, Koichi / Shimizu, Takayoshi / Matsuda, Shuichi / Otsuki, Bungo

World neurosurgery

2024

Abstract: Objective: This study aimed to quantify the change in pressure on the cage during compression manipulation in lumbar interbody fusion. While the procedure involves applying compression between pedicle screws to press the cage against the endplate, the ... ...

Abstract	Objective: This study aimed to quantify the change in pressure on the cage during compression manipulation in lumbar interbody fusion. While the procedure involves applying compression between pedicle screws to press the cage against the endplate, the exact compression force remains elusive. We hypothesize that an intact facet joint might serve as a fulcrum, potentially reducing cage pressure. Methods: Pressure on the intervertebral disc cage was measured during compression manipulation in 4 donor cadavers undergoing lumbar interbody fusion. Unilateral facetectomy models with both normal and parallel compression and bilateral facetectomy models were included. A transforaminal lumbar interbody fusion cage with a built-in load cell measured the compression force. Results: Pressure data from 14 discs indicated a consistent precompression pressure average of 68.16 N. Following compression, pressures increased to 125.99 N and 140.84 N for normal and parallel compression postunilateral facetectomy, respectively, and to 154.58 N and 150.46 N for bilateral models. A strong linear correlation (correlation coefficient: 0.967, P < 0.0001) between precompression and postcompression pressures emphasized the necessity of sufficient precompression pressure for achieving desired postcompression outcomes. None of the data showed a decrease in compression force to the cage with the compression maneuver. Conclusions: Both normal and parallel compression maneuvers effectively increased the pressure on the cage, irrespective of the facet joint resection status. Compression manipulation consistently enhanced compressive force on the cage. However, when baseline pressure is low, the manipulation might not yield significant increases in compression force. This underlines the essential role of meticulous precompression preparation in enhancing surgical outcomes.
Language	English
Publishing date	2024-03-21
Publishing country	United States
Document type	Journal Article
ZDB-ID	2534351-8
ISSN	1878-8769 ; 1878-8750
ISSN (online)	1878-8769
ISSN	1878-8750
DOI	10.1016/j.wneu.2024.03.080
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Zs.A 1159: Show issues

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Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

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Article: Sagittal Section Hounsfield Units of the Upper Instrumented Vertebrae as a Predictor of Proximal Junctional Vertebral Fractures Following Adult Spinal Deformity Surgery.

Murata, Koichi / Otsuki, Bungo / Shimizu, Takayoshi / Sono, Takashi / Fujibayashi, Shunsuke / Matsuda, Shuichi

Asian spine journal

2024

Abstract: Study design: A retrospective observational study.: Purpose: This study aimed to determine an accurate and convenient screening method for predicting proximal junctional fractures (PJFr) following surgery for adult spinal deformity (ASD) using ... ...

Abstract	Study design: A retrospective observational study. Purpose: This study aimed to determine an accurate and convenient screening method for predicting proximal junctional fractures (PJFr) following surgery for adult spinal deformity (ASD) using computed tomography (CT)-based measurement of Hounsfield units (HUs). Overview of literature: CT-based measurement of HUs is an alternative tool for assessing bone mineral density. However, the optimal method for predicting adjacent vertebral fractures following spinal fusion using HUs remains unclear. Methods: This retrospective observational study included 42 patients who underwent reconstructive surgery for ASD. Elliptical regions of interest (ROIs) on the axial section and rectangular ROIs on the sagittal section were placed at the upper instrumented vertebrae (UIV), UIV+1, and UIV+2. In addition, the HU value of the L2 vertebra was used as the representative. Results: PJFr occurred in 28.6% of patients within 2 years following surgery. The HU values obtained from the axial sections of L2, UIV, UIV+1, and UIV+2 were not significantly associated with the incidence of PJFr within 2 years, except for the ROI set in the lower region of the L2 vertebra. However, the HU value of the anterior third of the UIV in the sagittal section was significantly lower in the PJFr group than in the nonPJFr group (87.0 vs. 160.3, p =0.001). A UIV HU value of <100 was associated with a higher incidence of PJFr than an HU vaue of >100 (p <0.05). Conclusions: Measurements of HU in the anterior one-third of the UIV in the sagittal section demonstrated predictive ability for PJFr following ASD surgery. A UIV HU value of <100 emerged as a risk factor for PJFr.
Language	English
Publishing date	2024-04-23
Publishing country	Korea (South)
Document type	Journal Article
ZDB-ID	2559763-2
ISSN	1976-7846 ; 1976-1902
ISSN (online)	1976-7846
ISSN	1976-1902
DOI	10.31616/asj.2023.0339
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Zs.A 6861: Show issues

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Article ; Online: Differences in joint angles during pole vaulting between male pole vaulters with and without chronic low back pain

Enoki Shota / Kuramochi Rieko / Nakayama Koichi / Takigawa Hiroko / Shimizu Takuya

Biomedical Human Kinetics, Vol 15, Iss 1, Pp 131-

2023 Volume 138

Abstract: Study aim: To determine the difference in joint angles of the shoulder, hip, and trunk (angle of the upper torso and lower torso) during vaulting between male pole vaulters with and without chronic low back pain (LBP) and to examine the relationship ... ...

Abstract	Study aim: To determine the difference in joint angles of the shoulder, hip, and trunk (angle of the upper torso and lower torso) during vaulting between male pole vaulters with and without chronic low back pain (LBP) and to examine the relationship between the range of motion (ROM) and maximum angle of the same joint during vaulting in all participants.
Keywords	back pain ; lumbago ; track and field ; 3d-dlt ; Sports medicine ; RC1200-1245 ; Physiology ; QP1-981
Language	English
Publishing date	2023-01-01T00:00:00Z
Publisher	Sciendo
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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