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Article: Herbal product use patterns and possible herb-drug interactions among older adults in Turkey

Taneri, Petek Eylul / Akis, Nalan / Karaalp, Atila

Journal of herbal medicine. 2021 Oct., v. 29

2021

Abstract: Traditional and Complementary medicine use is on the increase universally. In this descriptive study, the aim is to evaluate the frequency and determinants of herbal product use, as well as determine possible drug-herb interactions among older ... ...

Abstract	Traditional and Complementary medicine use is on the increase universally. In this descriptive study, the aim is to evaluate the frequency and determinants of herbal product use, as well as determine possible drug-herb interactions among older individuals who live in rural and urban areas.The study was carried out with individuals 65 years or older in one urban and five rural neighborhoods in Bursa, Turkey. The data was collected during face-to-face interviews using a questionnaire comprising 43 questions. The participants were asked about the drugs and herb/herbal products they use and then the possible drug-herb interactions were evaluated using Micromedex®.Among the participants, 82.2 % reported using at least one drug regularly, and 18.3 % used at least one herb/herbal product in the past year (rural 26.1 %, urban 13.4 %). Most commonly used herb/herbal products were plane tree leaves and black cumin. Herbal product use was seen more among those experiencing difficulties accessing health care and living alone. Among those using drug and herb/herbal products concurrently, the possible drug-herb interaction rate was 7.5 %.Physicians providing health care services to geriatric populations should inquire about usage of drugs and herbs. Conventional medicine should be made accessible to every older adult, and it should be ensured that they do not have to resort to complementary therapies that could harm their health.
Keywords	Nigella sativa ; alternative medicine ; descriptive studies ; health services ; herbal medicines ; medicine ; questionnaires ; trees
Language	English
Dates of publication	2021-10
Publishing place	Elsevier GmbH
Document type	Article
ISSN	2210-8033
DOI	10.1016/j.hermed.2021.100487
Database	NAL-Catalogue (AGRICOLA)

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Article: A 7-Step Guideline for Qualitative Synthesis and Meta-Analysis of Observational Studies in Health Sciences.

Glisic, Marija / Raguindin, Peter Francis / Gemperli, Armin / Taneri, Petek Eylul / Salvador, Dante Jr / Voortman, Trudy / Marques Vidal, Pedro / Papatheodorou, Stefania I / Kunutsor, Setor K / Bano, Arjola / Ioannidis, John P A / Muka, Taulant

Public health reviews

2023 Volume 44, Page(s) 1605454

Abstract: Objectives: ...

Abstract	Objectives:
Language	English
Publishing date	2023-05-16
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	217531-9
ISSN	2107-6952 ; 0301-0422
ISSN (online)	2107-6952
ISSN	0301-0422
DOI	10.3389/phrs.2023.1605454
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Article ; Online: Risk Prediction Models of Natural Menopause Onset: A Systematic Review.

Raeisi-Dehkordi, Hamidreza / Kummer, Stefanie / Francis Raguindin, Peter / Dejanovic, Gordana / Eylul Taneri, Petek / Cardona, Isabel / Kastrati, Lum / Minder, Beatrice / Voortman, Trudy / Marques-Vidal, Pedro / Dhana, Klodian / Glisic, Marija / Muka, Taulant

The Journal of clinical endocrinology and metabolism

2022 Volume 107, Issue 10, Page(s) 2934–2944

Abstract: Context: Predicting the onset of menopause is important for family planning and to ensure prompt intervention in women at risk of developing menopause-related diseases.: Objective: We aimed to summarize risk prediction models of natural menopause ... ...

Abstract	Context: Predicting the onset of menopause is important for family planning and to ensure prompt intervention in women at risk of developing menopause-related diseases. Objective: We aimed to summarize risk prediction models of natural menopause onset and their performance. Methods: Five bibliographic databases were searched up to March 2022. We included prospective studies on perimenopausal women or women in menopausal transition that reported either a univariable or multivariable model for risk prediction of natural menopause onset. Two authors independently extracted data according to the CHARMS (critical appraisal and data extraction for systematic reviews of prediction modelling studies) checklist. Risk of bias was assessed using a prediction model risk of bias assessment tool (PROBAST). Results: Of 8132 references identified, we included 14 articles based on 8 unique studies comprising 9588 women (mainly Caucasian) and 3289 natural menopause events. All included studies used onset of natural menopause (ONM) as outcome, while 4 studies also predicted early ONM. Overall, there were 180 risk prediction models investigated, with age, anti-Müllerian hormone, and follicle-stimulating hormone being the most investigated predictors. Estimated C-statistic for the prediction models ranged from 0.62 to 0.95. Although all studies were rated at high risk of bias mainly due to the methodological concerns related to the statistical analysis, their applicability was satisfactory. Conclusion: Predictive performance and generalizability of current prediction models on ONM is limited given that these models were generated from studies at high risk of bias and from specific populations/ethnicities. Although in certain settings such models may be useful, efforts to improve their performance are needed as use becomes more widespread.
MeSH term(s)	Anti-Mullerian Hormone ; Female ; Follicle Stimulating Hormone ; Humans ; Menopause ; Prospective Studies
Chemical Substances	Anti-Mullerian Hormone (80497-65-0) ; Follicle Stimulating Hormone (9002-68-0)
Language	English
Publishing date	2022-07-31
Publishing country	United States
Document type	Journal Article ; Systematic Review ; Research Support, Non-U.S. Gov't
ZDB-ID	3029-6
ISSN	1945-7197 ; 0021-972X
ISSN (online)	1945-7197
ISSN	0021-972X
DOI	10.1210/clinem/dgac461
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Article ; Online: Protocol for the development of a core outcome set for neonatal sepsis (NESCOS)

Petek Eylul Taneri / Jamie J. Kirkham / Eleanor J. Molloy / Linda Biesty / Richard A. Polin / James L. Wynn / Barbara J. Stoll / Niranjan Kissoon / Kondwani Kawaza / Mandy Daly / Aoife Branagan / Lívia Nagy Bonnard / Eric Giannoni / Tobias Strunk / Magdalena Ohaja / Kenneth Mugabe / Denise Suguitani / Fiona Quirke / Declan Devane

PLoS ONE, Vol 18, Iss

2023 Volume 12

Keywords	Medicine ; R ; Science ; Q
Language	English
Publishing date	2023-01-01T00:00:00Z
Publisher	Public Library of Science (PLoS)
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Buckwheat and Cardiometabolic Health: A Systematic Review and Meta-Analysis.

Llanaj, Erand / Ahanchi, Noushin Sadat / Dizdari, Helga / Taneri, Petek Eylul / Niehot, Christa D / Wehrli, Faina / Khatami, Farnaz / Raeisi-Dehkordi, Hamidreza / Kastrati, Lum / Bano, Arjola / Glisic, Marija / Muka, Taulant

Journal of personalized medicine

2022 Volume 12, Issue 12

Abstract: Buckwheat (BW) is suggested to have beneficial effects, but evidence on how it affects cardiometabolic health (CMH) is not yet established. We aimed to assess the effects of BW and/or its related bioactive compounds on cardiovascular disease (CVD) risk ... ...

Abstract	Buckwheat (BW) is suggested to have beneficial effects, but evidence on how it affects cardiometabolic health (CMH) is not yet established. We aimed to assess the effects of BW and/or its related bioactive compounds on cardiovascular disease (CVD) risk markers in adults. Five databases were searched for eligible studies. Observational prospective studies, nonrandomized or randomized trials were considered if they assessed BW, rutin or quercetin-3-glucoside intake and CVD risk markers. We adhered to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines for reporting. We selected 16 human studies based on 831 subjects with mild metabolic disturbances, such as hypercholesterolemia, diabetes and/or overweight. Eight studies, investigating primarily grain components, were included in the meta-analyses (
Language	English
Publishing date	2022-11-22
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2662248-8
ISSN	2075-4426
ISSN	2075-4426
DOI	10.3390/jpm12121940
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Article ; Online: Protocol for the development of a core outcome set for neonatal sepsis (NESCOS).

Taneri, Petek Eylul / Kirkham, Jamie J / Molloy, Eleanor J / Biesty, Linda / Polin, Richard A / Wynn, James L / Stoll, Barbara J / Kissoon, Niranjan / Kawaza, Kondwani / Daly, Mandy / Branagan, Aoife / Bonnard, Lívia Nagy / Giannoni, Eric / Strunk, Tobias / Ohaja, Magdalena / Mugabe, Kenneth / Suguitani, Denise / Quirke, Fiona / Devane, Declan

PloS one

2023 Volume 18, Issue 12, Page(s) e0295325

Abstract: Neonatal sepsis is a serious public health problem; however, there is substantial heterogeneity in the outcomes measured and reported in research evaluating the effectiveness of the treatments. Therefore, we aim to develop a Core Outcome Set (COS) for ... ...

Abstract	Neonatal sepsis is a serious public health problem; however, there is substantial heterogeneity in the outcomes measured and reported in research evaluating the effectiveness of the treatments. Therefore, we aim to develop a Core Outcome Set (COS) for studies evaluating the effectiveness of treatments for neonatal sepsis. Since a systematic review of key outcomes from randomised trials of therapeutic interventions in neonatal sepsis was published recently, we will complement this with a qualitative systematic review of the key outcomes of neonatal sepsis identified by parents, other family members, parent representatives, healthcare providers, policymakers, and researchers. We will interpret the outcomes of both studies using a previously established framework. Stakeholders across three different groups i.e., (1) researchers, (2) healthcare providers, and (3) patients' parents/family members and parent representatives will rate the importance of the outcomes in an online Real-Time Delphi Survey. Afterwards, consensus meetings will be held to agree on the final COS through online discussions with key stakeholders. This COS is expected to minimize outcome heterogeneity in measurements and publications, improve comparability and synthesis, and decrease research waste.
MeSH term(s)	Infant, Newborn ; Humans ; Neonatal Sepsis/therapy ; Research Design ; Delphi Technique ; Consensus ; Outcome Assessment, Health Care/methods ; Treatment Outcome ; Systematic Reviews as Topic
Language	English
Publishing date	2023-12-05
Publishing country	United States
Document type	Journal Article
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0295325
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: A 7-Step Guideline for Qualitative Synthesis and Meta-Analysis of Observational Studies in Health Sciences

Glisic, Marija / Raguindin, Peter Francis / Gemperli, Armin / Taneri, Petek Eylul / Salvador, Dante Jr / Voortman, Trudy / Marques Vidal, Pedro / Papatheodorou, Stefania I. / Kunutsor, Setor K. / Bano, Arjola / Ioannidis, John P.A. / Muka, Taulant

Public Health Reviews

2023 Volume 44

Abstract: Objectives: To provide a step-by-step, easy-to-understand, practical guide for systematic review and meta-analysis of observational studies. Methods: A multidisciplinary team of researchers with extensive experience in observational studies and ... ...

Abstract	Objectives: To provide a step-by-step, easy-to-understand, practical guide for systematic review and meta-analysis of observational studies. Methods: A multidisciplinary team of researchers with extensive experience in observational studies and systematic review and meta-analysis was established. Previous guidelines in evidence synthesis were considered. Results: There is inherent variability in observational study design, population, and analysis, making evidence synthesis challenging. We provided a framework and discussed basic meta-analysis concepts to assist reviewers in making informed decisions. We also explained several statistical tools for dealing with heterogeneity, probing for bias, and interpreting findings. Finally, we briefly discussed issues and caveats for translating results into clinical and public health recommendations. Our guideline complements “A 24-step guide on how to design, conduct, and successfully publish a systematic review and meta-analysis in medical research” and addresses peculiarities for observational studies previously unexplored. Conclusion: We provided 7 steps to synthesize evidence from observational studies. We encourage medical and public health practitioners who answer important questions to systematically integrate evidence from observational studies and contribute evidence-based decision-making in health sciences.
Keywords	cohort studies ; cross-sectional studies ; evidence-based approach ; observational study ; systematic review and meta-analysis
Subject code	306
Language	English
Publishing country	nl
Document type	Article ; Online
ZDB-ID	217531-9
ISSN	2107-6952 ; 0301-0422
ISSN (online)	2107-6952
ISSN	0301-0422
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Prognostic models in COVID-19 infection that predict severity: a systematic review.

Buttia, Chepkoech / Llanaj, Erand / Raeisi-Dehkordi, Hamidreza / Kastrati, Lum / Amiri, Mojgan / Meçani, Renald / Taneri, Petek Eylul / Ochoa, Sergio Alejandro Gómez / Raguindin, Peter Francis / Wehrli, Faina / Khatami, Farnaz / Espínola, Octavio Pano / Rojas, Lyda Z / de Mortanges, Aurélie Pahud / Macharia-Nimietz, Eric Francis / Alijla, Fadi / Minder, Beatrice / Leichtle, Alexander B / Lüthi, Nora /

Ehrhard, Simone / Que, Yok-Ai / Fernandes, Laurenz Kopp / Hautz, Wolf / Muka, Taulant

European journal of epidemiology

2023 Volume 38, Issue 4, Page(s) 355–372

Abstract: Current evidence on COVID-19 prognostic models is inconsistent and clinical applicability remains controversial. We performed a systematic review to summarize and critically appraise the available studies that have developed, assessed and/or validated ... ...

Abstract	Current evidence on COVID-19 prognostic models is inconsistent and clinical applicability remains controversial. We performed a systematic review to summarize and critically appraise the available studies that have developed, assessed and/or validated prognostic models of COVID-19 predicting health outcomes. We searched six bibliographic databases to identify published articles that investigated univariable and multivariable prognostic models predicting adverse outcomes in adult COVID-19 patients, including intensive care unit (ICU) admission, intubation, high-flow nasal therapy (HFNT), extracorporeal membrane oxygenation (ECMO) and mortality. We identified and assessed 314 eligible articles from more than 40 countries, with 152 of these studies presenting mortality, 66 progression to severe or critical illness, 35 mortality and ICU admission combined, 17 ICU admission only, while the remaining 44 studies reported prediction models for mechanical ventilation (MV) or a combination of multiple outcomes. The sample size of included studies varied from 11 to 7,704,171 participants, with a mean age ranging from 18 to 93 years. There were 353 prognostic models investigated, with area under the curve (AUC) ranging from 0.44 to 0.99. A great proportion of studies (61.5%, 193 out of 314) performed internal or external validation or replication. In 312 (99.4%) studies, prognostic models were reported to be at high risk of bias due to uncertainties and challenges surrounding methodological rigor, sampling, handling of missing data, failure to deal with overfitting and heterogeneous definitions of COVID-19 and severity outcomes. While several clinical prognostic models for COVID-19 have been described in the literature, they are limited in generalizability and/or applicability due to deficiencies in addressing fundamental statistical and methodological concerns. Future large, multi-centric and well-designed prognostic prospective studies are needed to clarify remaining uncertainties.
MeSH term(s)	Adult ; Humans ; Adolescent ; Young Adult ; Middle Aged ; Aged ; Aged, 80 and over ; COVID-19 ; Prognosis ; Critical Care ; Intensive Care Units ; Hospitalization
Language	English
Publishing date	2023-02-25
Publishing country	Netherlands
Document type	Systematic Review ; Journal Article ; Review
ZDB-ID	632614-6
ISSN	1573-7284 ; 0393-2990
ISSN (online)	1573-7284
ISSN	0393-2990
DOI	10.1007/s10654-023-00973-x
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Association Between Ultra-Processed Food Intake and All-Cause Mortality: A Systematic Review and Meta-Analysis.

Taneri, Petek Eylul / Wehrli, Faina / Roa-Díaz, Zayne M / Itodo, Oche Adam / Salvador, Dante / Raeisi-Dehkordi, Hamidreza / Bally, Lia / Minder, Beatrice / Kiefte-de Jong, Jessica C / Laine, Jessica E / Bano, Arjola / Glisic, Marija / Muka, Taulant

American journal of epidemiology

2022 Volume 191, Issue 7, Page(s) 1323–1335

Abstract: Consumption of ultra-processed foods (UPF) has increased worldwide during the last decades because they are hyperpalatable, cheap, and ready-to-consume products. However, uncertainty exists about their impact on health. We conducted a systematic review ... ...

Abstract	Consumption of ultra-processed foods (UPF) has increased worldwide during the last decades because they are hyperpalatable, cheap, and ready-to-consume products. However, uncertainty exists about their impact on health. We conducted a systematic review and meta-analysis evaluating the association of UPF consumption with all-cause mortality risk. Five bibliographic databases were searched for relevant studies. Random effects models were used to calculate pooled relative risks (RRs) and 95% confidence intervals (CIs). Of 6,951 unique citations, 40 unique prospective cohort studies comprising 5,750,133 individuals were included; publication dates ranged from 1984 to 2021. Compared with low consumption, highest consumption of UPF (RR = 1.29, 95% CI: 1.17, 1.42), sugar-sweetened beverages (RR = 1.11, 95% CI, 1.04, 1.18), artificially sweetened beverages (RR = 1.14, 95% CI, 1.05, 1.22), and processed meat/red meat (RR = 1.15, 95% CI, 1.10, 1.21) were significantly associated with increased risk of mortality. However, breakfast cereals were associated with a lower mortality risk (RR = 0.85, 95% CI, 0.79, 0.92). This meta-analysis suggests that high consumption of UPF, sugar-sweetened beverages, artificially sweetened beverages, processed meat, and processed red meat might increase all-cause mortality, while breakfast cereals might decrease it. Future studies are needed to address lack of standardized methods in UPF categorization.
MeSH term(s)	Eating ; Fast Foods/adverse effects ; Humans ; Meat ; Prospective Studies ; Sweetening Agents/adverse effects
Chemical Substances	Sweetening Agents
Language	English
Publishing date	2022-02-26
Publishing country	United States
Document type	Journal Article ; Meta-Analysis ; Systematic Review
ZDB-ID	2937-3
ISSN	1476-6256 ; 0002-9262
ISSN (online)	1476-6256
ISSN	0002-9262
DOI	10.1093/aje/kwac039
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Protocol for the development of a core outcome set for neonatal sepsis (NESCOS).

Petek Eylul Taneri / Jamie J Kirkham / Eleanor J Molloy / Linda Biesty / Richard A Polin / James L Wynn / Barbara J Stoll / Niranjan Kissoon / Kondwani Kawaza / Mandy Daly / Aoife Branagan / Lívia Nagy Bonnard / Eric Giannoni / Tobias Strunk / Magdalena Ohaja / Kenneth Mugabe / Denise Suguitani / Fiona Quirke / Declan Devane

PLoS ONE, Vol 18, Iss 12, p e

2023 Volume 0295325

Abstract	Neonatal sepsis is a serious public health problem; however, there is substantial heterogeneity in the outcomes measured and reported in research evaluating the effectiveness of the treatments. Therefore, we aim to develop a Core Outcome Set (COS) for studies evaluating the effectiveness of treatments for neonatal sepsis. Since a systematic review of key outcomes from randomised trials of therapeutic interventions in neonatal sepsis was published recently, we will complement this with a qualitative systematic review of the key outcomes of neonatal sepsis identified by parents, other family members, parent representatives, healthcare providers, policymakers, and researchers. We will interpret the outcomes of both studies using a previously established framework. Stakeholders across three different groups i.e., (1) researchers, (2) healthcare providers, and (3) patients' parents/family members and parent representatives will rate the importance of the outcomes in an online Real-Time Delphi Survey. Afterwards, consensus meetings will be held to agree on the final COS through online discussions with key stakeholders. This COS is expected to minimize outcome heterogeneity in measurements and publications, improve comparability and synthesis, and decrease research waste.
Keywords	Medicine ; R ; Science ; Q
Subject code	306
Language	English
Publishing date	2023-01-01T00:00:00Z
Publisher	Public Library of Science (PLoS)
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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