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  1. Article ; Online: Diabetes in COVID-19 pandemic-prevalence, patient characteristics and adverse outcomes.

    Abdelhafiz, Ahmed H / Emmerton, Demelza / Sinclair, Alan J

    International journal of clinical practice

    2021  Volume 75, Issue 7, Page(s) e14112

    Abstract: ... the prevalence of diabetes in COVID-19 pandemic, effect of diabetes on clinical outcomes and to characterise ... characteristics.: Results: The prevalence of diabetes in COVID-19 patients appears similar ... of diabetes on outcomes and characteristics of patients at risk is not clear.: Objectives: To explore ...

    Abstract Background: Current literature on COVID-19 pandemic has identified diabetes as a common comorbidity in patients affected. However, the evidence that diabetes increases the risk of infection, effect of diabetes on outcomes and characteristics of patients at risk is not clear.
    Objectives: To explore the prevalence of diabetes in COVID-19 pandemic, effect of diabetes on clinical outcomes and to characterise the patients with diabetes affected by COVID-19.
    Methods: A literature review of articles published in English language and reported outcomes on prevalence and effect of diabetes on outcomes and patients' characteristics.
    Results: The prevalence of diabetes in COVID-19 patients appears similar to that in the general population. The evidence of diabetes increasing the risk of severe infection and adverse outcomes is substantial. The progression of the disease into acute respiratory distress syndrome, the requirement for intensive care admission or mechanical ventilation and mortality all have been increased by the presence of diabetes. Patients with diabetes at risk of COVID-19 appear to be obese, of older age, have uncontrolled glycaemia and have coexisting comorbidities especially cardiovascular disease and hypertension. Tight glycaemic control on admission to hospital using insulin infusion has shown some beneficial effects; however, the role of hypoglycaemic medications in the management of these patients is not yet clear.
    Conclusion: High risk group should be identified and prioritised in future vaccination programmes. Future research is required to optimise management of patients with diabetes and develop new ways to manage them via technological developments such as telecare.
    MeSH term(s) Aged ; COVID-19 ; Comorbidity ; Diabetes Mellitus/epidemiology ; Hospitalization ; Humans ; Pandemics ; Prevalence ; Respiration, Artificial ; SARS-CoV-2
    Language English
    Publishing date 2021-03-14
    Publishing country India
    Document type Journal Article ; Review
    ZDB-ID 1386246-7
    ISSN 1742-1241 ; 1368-5031
    ISSN (online) 1742-1241
    ISSN 1368-5031
    DOI 10.1111/ijcp.14112
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Diabetes mellitus in the context of COVID-19

    Carlos Enrique Medina Campaña / Elizabeth Hernández González

    Revista Científica Estudiantil 2 de Diciembre, Vol 3, Iss 3, Pp e81-e

    2020  Volume 81

    Abstract: ... 2019 (COVID-19) pandemic. DM represents an important risk factor for adverse outcomes in patients ... treatment options among patients with COVID-19 and diabetes mellitus. Method: a literature review was ... its Spanish translation “diabetes mellitus”, “infección por coronavirus”. Development: COVID-19 and diabetic ...

    Abstract A high prevalence of diabetes mellitus (DM) represents a challenge during the coronavirus disease 2019 (COVID-19) pandemic. DM represents an important risk factor for adverse outcomes in patients with COVID-19. Objective: to describe the clinical, epidemiological and molecular characteristics; including treatment options among patients with COVID-19 and diabetes mellitus. Method: a literature review was conducted in articles published by peer-reviewed journals up to June 2020. SciELO and PubMed databases were screened in search of articles. The search terms included diabetes mellitus, coronavirus infection, and its Spanish translation “diabetes mellitus”, “infección por coronavirus”. Development: COVID-19 and diabetic patients may be predisposed to immune dysfunction that results in severe late illness. Most patients with mild infection can continue with the usual antihyperglycemic medications. The result of the use of corticosteroids is not yet clear. There are safety concerns regarding treatment with chloroquine/hydroxychloroquine, due to its hypoglycemic role and adverse effects. Conclusions: the molecular and pathophysiological mechanisms between COVID-19 and diabetes mellitus are still not fully understood. The poor prognosis observed in these patients requires the creation of a novel treatment protocol.
    Keywords diabetes ; mellitus diabetes ; coronavirus infections ; sars-cov-2 ; Public aspects of medicine ; RA1-1270
    Subject code 571
    Language English
    Publishing date 2020-08-01T00:00:00Z
    Publisher Universidad de Ciencias Médicas de Granma
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Diabetes mellitus in the context of COVID-19 ; La diabetes mellitus en el contexto de la COVID-19

    Medina Campaña, Carlos Enrique / Hernández González, Elizabeth

    Student Scientific Journal "2 de Diciembre"; Vol. 3, No.; e81 ; Revista científica estudiantil 2 de Diciembre; Vol. 3, No. 3 (2020): JULIO - SEPTIEMBRE; e81

    2020  Volume 3, Issue : JULIO - SEPTIEMBRE

    Abstract: ... 2019 (COVID-19) pandemic. DM represents an important risk factor for adverse outcomes in patients with ... treatment options among patients with COVID-19 and diabetes mellitus.Method: a literature review was ... Spanish translation “diabetes mellitus”, “infección por coronavirus”.Development: COVID-19 and diabetic ...

    Abstract A high prevalence of diabetes mellitus (DM) represents a challenge during the coronavirus disease 2019 (COVID-19) pandemic. DM represents an important risk factor for adverse outcomes in patients with COVID-19.Objective: to describe the clinical, epidemiological and molecular characteristics; including treatment options among patients with COVID-19 and diabetes mellitus.Method: a literature review was conducted in articles published by peer-reviewed journals up to June 2020. SciELO and PubMed databases were screened in search of articles. The search terms included diabetes mellitus, coronavirus infection, and its Spanish translation “diabetes mellitus”, “infección por coronavirus”.Development: COVID-19 and diabetic patients may be predisposed to immune dysfunction that results in severe late illness. Most patients with mild infection can continue with the usual antihyperglycemic medications. The result of the use of corticosteroids is not yet clear. There are safety concerns regarding treatment with chloroquine/hydroxychloroquine, due to its hypoglycemic role and adverse effects.Conclusions: the molecular and pathophysiological mechanisms between COVID-19 and diabetes mellitus are still not fully understood. The poor prognosis observed in these patients requires the creation of a novel treatment protocol.

    Introducción: una alta prevalencia de la diabetes mellitus representa un desafío durante la pandemia de la enfermedad por coronavirus 2019 o COVID-19. La diabetes mellitus constituye un importante factor de riesgo de complicaciones en pacientes con COVID-19.Objetivo: describir las características clínicas, epidemiológicas y moleculares; así como opciones de tratamiento en los pacientes con COVID-19 y diabetes mellitus.Método: se realizó una revisión bibliográfica en artículos publicados en revistas biomédicas revisadas por pares hasta junio de 2020. Se revisaron las bases de datos SciELO y PubMed. Los términos de búsqueda incluyeron diabetes mellitus, coronavirus infection, y su traducción al español «diabetes mellitus», «infección por coronavirus».Desarrollo: La COVID-19 y los pacientes diabéticos pueden estar predispuestos a una disfunción inmunológica que resulta en una enfermedad tardía severa. La mayoría de los pacientes con infección leve pueden continuar con los medicamentos anti-hiperglucémicos habituales. El resultado del uso de corticoesteroides aún no está claro. Existen preocupaciones de seguridad con respecto al tratamiento con cloroquina/hidroxicloroquina, en relación con su función hipoglucémica y demás efectos adversos.Conclusiones: los mecanismos moleculares fisiopatológicos entre la COVID-19 y la diabetes mellitus todavía no están del todo dilucidados. El mal pronóstico que se observa en pacientes con ambas enfermedades requiere la creación de nuevos protocolos de tratamiento.
    Keywords Diabetes ; Mellitus diabetes ; Coronavirus Infections ; SARS-Cov-2 ; Diabetes Mellitus ; Infeción por Coronavirus ; covid19
    Language English
    Publishing date 2020-08-18
    Publisher Centro Provincial de Información de Ciencias Médicas de Granma
    Publishing country cu
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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