LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 6 of total 6

Search options

  1. Article ; Online: Prolonged Unconsciousness Following Severe COVID-19.

    Abdo, Wilson F / Broerse, Catharina I / Grady, Bart P / Wertenbroek, Agnes A A C M / Vijlbrief, Onno / Buise, Marc P / Beukema, Menno / van der Kuil, Mark / Tuladhar, Anil M / Meijer, Frederick J A / van der Hoeven, Johannes G

    Neurology

    2020  Volume 96, Issue 10, Page(s) e1437–e1442

    Abstract: ... coronavirus disease 2019 (COVID-19)-related severe respiratory failure.: Methods: A case series of patients ... commands ranged from 8 to 31 days.: Conclusion: Prolonged unconsciousness in patients with severe ... who were admitted to the intensive care unit due to COVID-19-related acute respiratory failure is described ...

    Abstract Objective: We report a case series of patients with prolonged but reversible unconsciousness after coronavirus disease 2019 (COVID-19)-related severe respiratory failure.
    Methods: A case series of patients who were admitted to the intensive care unit due to COVID-19-related acute respiratory failure is described.
    Results: After cessation of sedatives, the described cases all showed a prolonged comatose state. Diagnostic neurologic workup did not show signs of devastating brain injury. The clinical pattern of awakening started with early eye opening without obeying commands and persistent flaccid weakness in all cases. Time between cessation of sedatives to the first moment of being fully responsive with obeying commands ranged from 8 to 31 days.
    Conclusion: Prolonged unconsciousness in patients with severe respiratory failure due to COVID-19 can be fully reversible, warranting a cautious approach for prognostication based on a prolonged state of unconsciousness.
    MeSH term(s) Adult ; Aged ; COVID-19/complications ; Coma/diagnostic imaging ; Coma/etiology ; Coma/pathology ; Female ; Humans ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Respiratory Insufficiency/complications ; Respiratory Insufficiency/etiology ; Time Factors ; Treatment Outcome ; White Matter/diagnostic imaging ; White Matter/pathology
    Language English
    Publishing date 2020-12-21
    Publishing country United States
    Document type Case Reports ; Journal Article ; Multicenter Study
    ZDB-ID 207147-2
    ISSN 1526-632X ; 0028-3878
    ISSN (online) 1526-632X
    ISSN 0028-3878
    DOI 10.1212/WNL.0000000000011355
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article ; Online: Author Response: Prolonged Unconsciousness Following Severe COVID-19.

    Abdo, Wilson F / Van der Hoeven, Johannes G

    Neurology

    2021  Volume 97, Issue 11, Page(s) 557

    MeSH term(s) Brain Injuries ; COVID-19 ; Humans ; SARS-CoV-2 ; Unconsciousness/etiology
    Language English
    Publishing date 2021-09-13
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 207147-2
    ISSN 1526-632X ; 0028-3878
    ISSN (online) 1526-632X
    ISSN 0028-3878
    DOI 10.1212/WNL.0000000000012548
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article ; Online: Editors' Note: Prolonged Unconsciousness Following Severe COVID-19.

    Ganesh, Aravind / Galetta, Steven

    Neurology

    2021  Volume 97, Issue 11, Page(s) 555

    MeSH term(s) COVID-19 ; Humans ; SARS-CoV-2 ; Unconsciousness/etiology
    Language English
    Publishing date 2021-09-13
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 207147-2
    ISSN 1526-632X ; 0028-3878
    ISSN (online) 1526-632X
    ISSN 0028-3878
    DOI 10.1212/WNL.0000000000012544
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article ; Online: Reader Response: Prolonged Unconsciousness Following Severe COVID-19.

    Machado, Calixto

    Neurology

    2021  Volume 97, Issue 11, Page(s) 555–556

    MeSH term(s) Brain Injuries ; COVID-19 ; Humans ; SARS-CoV-2 ; Unconsciousness/etiology
    Language English
    Publishing date 2021-09-13
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 207147-2
    ISSN 1526-632X ; 0028-3878
    ISSN (online) 1526-632X
    ISSN 0028-3878
    DOI 10.1212/WNL.0000000000012546
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Article ; Online: Reader Response: Prolonged Unconsciousness Following Severe COVID-19.

    Vogrig, Alberto / Valente, Mariarosaria / Nilo, Annacarmen / Gigli, Gian Luigi

    Neurology

    2021  Volume 97, Issue 11, Page(s) 556

    MeSH term(s) Brain Injuries ; COVID-19 ; Humans ; SARS-CoV-2 ; Unconsciousness/etiology
    Language English
    Publishing date 2021-09-13
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 207147-2
    ISSN 1526-632X ; 0028-3878
    ISSN (online) 1526-632X
    ISSN 0028-3878
    DOI 10.1212/WNL.0000000000012547
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  6. Article ; Online: Prolonged Unconsciousness is Common in COVID-19 and Associated with Hypoxemia.

    Waldrop, Greer / Safavynia, Seyed A / Barra, Megan E / Agarwal, Sachin / Berlin, David A / Boehme, Amelia K / Brodie, Daniel / Choi, Jacky M / Doyle, Kevin / Fins, Joseph J / Ganglberger, Wolfgang / Hoffman, Katherine / Mittel, Aaron M / Roh, David / Mukerji, Shibani S / Der Nigoghossian, Caroline / Park, Soojin / Schenck, Edward J / Salazar-Schicchi, John /
    Shen, Qi / Sholle, Evan / Velazquez, Angela G / Walline, Maria C / Westover, M Brandon / Brown, Emery N / Victor, Jonathan / Edlow, Brian L / Schiff, Nicholas D / Claassen, Jan

    Annals of neurology

    2022  Volume 91, Issue 6, Page(s) 740–755

    Abstract: ... hospitals because of severe coronavirus disease 2019 (COVID-19), required endotracheal intubation ... of an arterial partial pressure of oxygen (PaO: Interpretation: Survivors of severe COVID-19 commonly recover ... Objective: The purpose of this study was to estimate the time to recovery of command-following and ...

    Abstract Objective: The purpose of this study was to estimate the time to recovery of command-following and associations between hypoxemia with time to recovery of command-following.
    Methods: In this multicenter, retrospective, cohort study during the initial surge of the United States' pandemic (March-July 2020) we estimate the time from intubation to recovery of command-following, using Kaplan Meier cumulative-incidence curves and Cox proportional hazard models. Patients were included if they were admitted to 1 of 3 hospitals because of severe coronavirus disease 2019 (COVID-19), required endotracheal intubation for at least 7 days, and experienced impairment of consciousness (Glasgow Coma Scale motor score <6).
    Results: Five hundred seventy-one patients of the 795 patients recovered command-following. The median time to recovery of command-following was 30 days (95% confidence interval [CI] = 27-32 days). Median time to recovery of command-following increased by 16 days for patients with at least one episode of an arterial partial pressure of oxygen (PaO
    Interpretation: Survivors of severe COVID-19 commonly recover consciousness weeks after cessation of mechanical ventilation. Long recovery periods are associated with more severe hypoxemia. This relationship is not explained by sedation or brain injury identified on clinical imaging and should inform decisions about life-sustaining therapies. ANN NEUROL 2022;91:740-755.
    MeSH term(s) Brain Injuries/complications ; COVID-19/complications ; Cohort Studies ; Humans ; Hypoxia ; Retrospective Studies ; Unconsciousness/complications
    Language English
    Publishing date 2022-04-21
    Publishing country United States
    Document type Journal Article ; Multicenter Study ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 80362-5
    ISSN 1531-8249 ; 0364-5134
    ISSN (online) 1531-8249
    ISSN 0364-5134
    DOI 10.1002/ana.26342
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top