Article: Paper biosensors for detecting elevated IL-6 levels in blood and respiratory samples from COVID-19 patients.
Sensors and actuators. B, Chemical
2020 Volume 330, Page(s) 129333
Abstract: ... We introduce biosensors aimed at detecting severe cases of COVID-19 in decentralized healthcare settings ... Decentralizing COVID-19 care reduces contagions and affords a better use of hospital resources ... been proposed as a prognosis biomarker of COVID-19. This is achieved by combining a paper-based signal ...
| Abstract | Decentralizing COVID-19 care reduces contagions and affords a better use of hospital resources. We introduce biosensors aimed at detecting severe cases of COVID-19 in decentralized healthcare settings. They consist of a paper immunosensor interfaced with a smartphone. The immunosensors have been designed to generate intense colorimetric signals when the sample contains ultralow concentrations of IL-6, which has been proposed as a prognosis biomarker of COVID-19. This is achieved by combining a paper-based signal amplification mechanism with polymer-filled reservoirs for dispensing antibody-decorated nanoparticles and a bespoken app for color quantification. With this design we achieved a low limit of detection (LOD) of 10 |
|---|---|
| Language | English |
| Publishing date | 2020-12-14 |
| Publishing country | Switzerland |
| Document type | Journal Article |
| ZDB-ID | 1021505-0 |
| ISSN | 0925-4005 |
| ISSN | 0925-4005 |
| DOI | 10.1016/j.snb.2020.129333 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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