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  1. Article: Splenic abscess: An unusual presentation of COVID-19?

    Al-Ozaibi, Labib S. / Alshaikh, Mohammed O. / Makhdoom, Maahroo / Alzoabi, Osama M. / Busharar, Hajar A. / Keloth, Tasnim R.

    Dubai Med. J

    Abstract: Most patients with coronavirus disease 2019 (COVID-19) present with respiratory symptoms that range ... diarrhea, and fever. He tested positive for COVID-19. Computed tomography (CT) abdomen showed the presence ... with multiorgan failure and died on postoperative day 16. COVID-19 mainly affects the respiratory system ...

    Abstract Most patients with coronavirus disease 2019 (COVID-19) present with respiratory symptoms that range from mild symptoms to severe illness leading to mortality. Some might be asymptomatic and others may present with unusual presentations. A 55-year-old male with a past history of ischemic stroke, ischemic heart disease, and type 2 diabetes mellitus presented with right-sided weakness and a history of abdominal pain, diarrhea, and fever. He tested positive for COVID-19. Computed tomography (CT) abdomen showed the presence of splenic abscess and small intraperitoneal gas indicating pneumoperitoneum. Laparotomy revealed ruptured splenic abscess and splenectomy was done. The patient continued to show features of severe sepsis with multiorgan failure and died on postoperative day 16. COVID-19 mainly affects the respiratory system but extrapulmonary affection has been reported. Direct invasion and damage to the organs by the virus could be the reason behind the development of the extrapulmonary manifestations.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #798889
    Database COVID19

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  2. Article ; Online: Splenic Abscess

    Al-Ozaibi, Labib S. / Alshaikh, Mohammed O. / Makhdoom, Maahroo / Alzoabi, Osama M. / Busharar, Hajar A. / Keloth, Tasnim R.

    Dubai Medical Journal

    An Unusual Presentation of COVID-19?

    2020  , Page(s) 1–4

    Keywords covid19
    Language English
    Publisher S. Karger AG
    Publishing country ch
    Document type Article ; Online
    ISSN 2571-726X
    DOI 10.1159/000509644
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Splenic Abscess

    Labib S. Al-Ozaibi / Mohammed O. Alshaikh / Maahroo Makhdoom / Osama M. Alzoabi / Hajar A. Busharar / Tasnim R. Keloth

    Dubai Medical Journal, Pp 1-

    An Unusual Presentation of COVID-19?

    2020  Volume 4

    Abstract: Most patients with coronavirus disease 2019 (COVID-19) present with respiratory symptoms that range ... diarrhea, and fever. He tested positive for COVID-19. Computed tomography (CT) abdomen showed the presence ... with multiorgan failure and died on postoperative day 16. COVID-19 mainly affects the respiratory system ...

    Abstract Most patients with coronavirus disease 2019 (COVID-19) present with respiratory symptoms that range from mild symptoms to severe illness leading to mortality. Some might be asymptomatic and others may present with unusual presentations. A 55-year-old male with a past history of ischemic stroke, ischemic heart disease, and type 2 diabetes mellitus presented with right-sided weakness and a history of abdominal pain, diarrhea, and fever. He tested positive for COVID-19. Computed tomography (CT) abdomen showed the presence of splenic abscess and small intraperitoneal gas indicating pneumoperitoneum. Laparotomy revealed ruptured splenic abscess and splenectomy was done. The patient continued to show features of severe sepsis with multiorgan failure and died on postoperative day 16. COVID-19 mainly affects the respiratory system but extrapulmonary affection has been reported. Direct invasion and damage to the organs by the virus could be the reason behind the development of the extrapulmonary manifestations.
    Keywords splenic abscess ; covid-19 ; novel coronavirus disease 2019 ; Medicine ; R ; covid19
    Language English
    Publishing date 2020-09-01T00:00:00Z
    Publisher Karger Publishers
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  4. Article ; Online: Rare and Unusual Follow-up Sequelae of Coronavirus Disease 2019: Splenic Mucormycosis in a Renal Transplant Recipient.

    Meshram, Hari Shankar / Kumar, Deepak / Kute, Vivek B

    Transplantation proceedings

    2021  Volume 54, Issue 6, Page(s) 1554–1556

    Abstract: Background: Coronavirus disease 2019 (COVID-19) is associated with adverse outcomes ... the double infection of mucormycosis and COVID-19 is a lethal combination but is rarely described ... kidney transplant recipient with diabetes who acquired severe COVID-19, followed by disseminated mucormycosis ...

    Abstract Background: Coronavirus disease 2019 (COVID-19) is associated with adverse outcomes in transplantation communities. Mucormycosis, although a rare infection, has been classically linked to organ transplantation and is associated with exceptionally high morbidity and mortality rates. In this pandemic era, the double infection of mucormycosis and COVID-19 is a lethal combination but is rarely described in the literature on organ transplantation.
    Case presentation: This article presents the case of a young kidney transplant recipient with diabetes who acquired severe COVID-19, followed by disseminated mucormycosis. The patient was a health care worker who developed severe COVID-19, for which he received remdesivir, anticoagulation, and dexamethasone. No immunomodulatory therapy was used. His maximum oxygen support was bilevel positive airway pressure ventilation. His sugar levels were frequently deranged during the stay. He developed secondary sepsis with Klebsiella, followed by nonhealing lung consolidation. He later developed pleural effusion and splenic abscess, which was detected incidentally. He underwent an emergency splenectomy, the culture of which yielded mucormycosis. Liposomal amphotericin B 5 mg/kg was administered. The patient deteriorated, and a repeat laparotomy yielded gastric perforation, with pus culture showing mucormycosis. The patient died after a long hospital stay.
    Conclusions: The diagnosis and management of this dual infection during the pandemic is extremely challenging. In this case, the unusual location of mucormycosis complicating COVID-19 calls for a meticulous approach to opportunistic fungal infections in organ transplant recipients who are positive for COVID-19, especially in those patients with diabetes.
    MeSH term(s) Anticoagulants ; Antifungal Agents/therapeutic use ; COVID-19 ; Dexamethasone ; Diabetes Mellitus/etiology ; Follow-Up Studies ; Humans ; Kidney Transplantation/adverse effects ; Male ; Mucormycosis/etiology ; Oxygen ; Splenic Diseases/diagnosis ; Sugars
    Chemical Substances Anticoagulants ; Antifungal Agents ; Sugars ; Dexamethasone (7S5I7G3JQL) ; Oxygen (S88TT14065)
    Language English
    Publishing date 2021-10-02
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 82046-5
    ISSN 1873-2623 ; 0041-1345
    ISSN (online) 1873-2623
    ISSN 0041-1345
    DOI 10.1016/j.transproceed.2021.09.010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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