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  1. Article ; Online: Coronavirus Positive Patients Presenting with Stroke-Like Symptoms.

    Alam, Shaista / Dharia, Robin N / Miller, Elan / Rincon, Fred / Tzeng, Diana L / Bell, Rodney D

    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association

    2021  Volume 30, Issue 4, Page(s) 105588

    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; COVID-19/complications ; COVID-19/diagnosis ; COVID-19/mortality ; COVID-19/therapy ; Diagnosis, Differential ; Female ; Humans ; Male ; Middle Aged ; Prognosis ; Risk Factors ; Stroke/diagnosis ; Stroke/etiology ; Stroke/mortality ; Stroke/therapy
    Language English
    Publishing date 2021-01-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1131675-5
    ISSN 1532-8511 ; 1052-3057
    ISSN (online) 1532-8511
    ISSN 1052-3057
    DOI 10.1016/j.jstrokecerebrovasdis.2020.105588
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Comments on coronavirus positive patients presenting with stroke-like symptoms.

    Au, Sunny Chi Lik / Ko, Callie Ka Li

    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association

    2021  Volume 30, Issue 7, Page(s) 105741

    MeSH term(s) COVID-19 ; Humans ; SARS-CoV-2 ; Stroke/diagnosis ; Stroke/therapy
    Language English
    Publishing date 2021-03-10
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 1131675-5
    ISSN 1532-8511 ; 1052-3057
    ISSN (online) 1532-8511
    ISSN 1052-3057
    DOI 10.1016/j.jstrokecerebrovasdis.2021.105741
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Characteristics of re-admitted adult patients infected with severe acute respiratory syndrome Coronavirus 2 After initial hospitalization at King Salman Armed Forces Hospital, Tabuk, Saudi Arabia.

    Albalawi, Hanaa / Albalawi, Rashed / Hamza, Riham / Galdagoun, Abdulaziz / Aljofi, Noura S / Elgohary, Khaled / Fallatah, Samira

    Saudi medical journal

    2023  Volume 44, Issue 7, Page(s) 647–654

    Abstract: ... were included.: Results: The commonest presenting symptoms were cough, fever, and dyspnea. The most ... more likely to be readmitted compared to younger patients. Regarding clinical characteristics ... critically ill patients were more likely to be readmitted than less severe cases. Patients with unilateral lung ...

    Abstract Objectives: To describe the clinical characteristics and possible risk factors associated with re-hospitalization within 30 days of discharge among hospitalized adult patients with confirmed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.
    Methods: This is a retrospective cohort study conducted at King Salman Armed Forces Hospital (KSAFH), Tabuk, Saudi Arabia over the period between March to November 2020. The study was conducted over 237 patients who had confirmed SARS-CoV-2 and fulfilled the study inclusion criteria (at least 14 years old, with subsequently discharged alive from the hospital) were included.
    Results: The commonest presenting symptoms were cough, fever, and dyspnea. The most frequent reported comorbid diseases were diabetes mellitus and hypertension. Half of cases were regarded as severe cases whereas 14.8% were critical cases. The rate of readmission was 5.9%. Older patients were more likely to be readmitted compared to younger patients. Regarding clinical characteristics, critically ill patients were more likely to be readmitted than less severe cases. Patients with unilateral lung shadow in chest x-ray, and those with positive history of Intensive care unit (ICU) admission were more likely to be readmitted compared to their peers. Regarding medical history, the only factor significantly associated with readmission were history of cerebrovascular accident (CVA), as 22.2% of those with CVA history compared to only 1.5% of those without CVA history were more likely to be readmitted. Among laboratory findings, high lymphocytic count (>3 per microliter) was significantly associate with likelihood for readmission.
    Conclusion: Readmission rate or patients hospitalization initially for Covid-19 was comparable to rates reported by most of other similar international studies. Further longitudinal larger multicentric study is warranted to have clearer image of the situation.
    MeSH term(s) Humans ; Adult ; Adolescent ; SARS-CoV-2 ; COVID-19/epidemiology ; Retrospective Studies ; Saudi Arabia/epidemiology ; Hospitalization ; Hospitals ; Stroke
    Language English
    Publishing date 2023-07-03
    Publishing country Saudi Arabia
    Document type Journal Article
    ZDB-ID 392302-2
    ISSN 1658-3175 ; 0379-5284
    ISSN (online) 1658-3175
    ISSN 0379-5284
    DOI 10.15537/smj.2023.44.7.20220713
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Covid-19-associated Coagulopathy as a Presentation of Coronavirus Disease 2019: a Patient Presents with a Large Stroke, Pulmonary Embolism, and Dvt

    Ramanathan, R. / Condit, D. / Krishnan, A. M. / Troy, P.

    Chest

    Abstract: ... in patients younger than 50 years of age have been described as presenting symptoms for patients found to have ... COVID-19 Most patients with COVID-19 present with constitutional and respiratory symptoms, symptoms ... of CAC Our patients was found to have a large right MCA stroke, PE and right lower extremity DVT She was ...

    Abstract SESSION TITLE: Medical Student/Resident Pulmonary Vascular Disease Posters SESSION TYPE: Med Student/Res Case Rep Postr PRESENTED ON: October 18-21, 2020 INTRODUCTION: Large-vessel strokes in patients younger than 50 years of age have been described as presenting symptoms for patients found to have COVID-19 Most patients with COVID-19 present with constitutional and respiratory symptoms, symptoms which range from asymptomatic disease to life-threatening disease including acute respiratory distress syndrome, acute kidney injury, multi-organ failure and death Here, we report a case of a patient presenting with both arterial and venous clots in the setting of COVID-19 that represents an extreme presentation of an entity now known as COVID-19 associated coagulopathy (CAC) CASE PRESENTATION: Our patient is a 74 year old female with past medical history of hypertension, hyperlipidemia and diabetes who presented after her daughter noticed that she was experiencing difficulty with balance She was taken to an outside hospital (OSH) where she was found to have left sided weakness and right sided gaze deviation History was notable for recent diagnosis of UTI as well as a new cough, dyspnea and dizziness that developed earlier in the day While at the OSH she suddenly became more unresponsive and was intubated for airway protection Her initial head CT showed a hyperdense right middle cerebral artery Intravenous tissue plasminogen activator was administered for her stroke and subsequently she was transferred to our hospital for further management A CTA head and neck was performed which showed a proximal right MCA occlusion (image 1) CT perfusion showed large infarct core as well as poor ASPECTS score (3-4) and she was therefore not a candidate for mechanical thrombectomy Incidentally, further chest imaging revealed a large pulmonary embolism (PE) in the right pulmonary artery, multiple segmental PE's and diffuse ground glass opacities (image 2) COVID-19 testing returned positive Bilateral lower extremity duplex was performed, this was significant for right soleal vein thrombus (image 3) The patient was started on a heparin infusion given her significant CAC despite the high risk of hemorrhagic transformation of her stroke Her condition improved and she was extubated on hospital day (HD) 4 and discharged to a skilled nursing facility on HD 20 Prior to discharge she was transitioned from heparin to rivaroxaban DISCUSSION: This case demonstrates the severity of CAC Our patients was found to have a large right MCA stroke, PE and right lower extremity DVT She was worked up extensively for other etiologies of her stroke but they were unrevealing The etiology of stroke was thought to be embolic of undetermined source and was most likely in the setting of COVID-19 CONCLUSIONS: CAC can be catastrophic for patients and can present with both arterial and venous thromboses Further studies are needed to elucidate the underlying pathophysiology of CAC and the optimal anticoagulation as well thrombolytic dosage regimens for thromboses secondary to CAC Reference #1: Avula A, Nalleballe K, Narula N, et al COVID-19 presenting as stroke [published online ahead of print, 2020 Apr 28] Brain Behav Immun 2020;S0889-1591(20)30685-1 doi:10 1016/j bbi 2020 04 077 Reference #2: Becker RC COVID-19 update: Covid-19-associated coagulopathy [published online ahead of print, 2020 May 15] J Thromb Thrombolysis 2020;1‐14 doi:10 1007/s11239-020-02134-3 DISCLOSURES: No relevant relationships by Daniel Condit, source=Web ResponseNo relevant relationships by Anand Muthu Krishnan, source=Web ResponseNo relevant relationships by Rudra Ramanathan, source=Web ResponseConsultant relationship with Boston Scientific Please note: $1001 - $5000 Added 06/01/2020 by Patrick Troy, source=Web Response, value=Consulting feeAdvisory Committee Member relationship with Boston Scientific Please note: $1001 - $5000 Added 06/01/2020 by Patrick Troy, source=Web Response, value=Consulting fee
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #871878
    Database COVID19

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