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  1. Article ; Online: Complex case of COVID-19 and infective endocarditis.

    Alizadeh, Katrin / Bucke, Danielle / Khan, Sadia

    BMJ case reports

    2021  Volume 14, Issue 8

    Abstract: ... dyspnoea. He tested positive for coronavirus (COVID-19), and subsequently, was admitted ... A 50-year-old man with no medical history of note presented with new onset of confusion and ... to the intensive care unit due to severe sepsis and acute renal failure requiring haemodialysis. Shortly afterwards, he was ...

    Abstract A 50-year-old man with no medical history of note presented with new onset of confusion and dyspnoea. He tested positive for coronavirus (COVID-19), and subsequently, was admitted to the intensive care unit due to severe sepsis and acute renal failure requiring haemodialysis. Shortly afterwards, he was intubated due to haemodynamic instability. His blood culture was positive for
    MeSH term(s) Bacteremia ; COVID-19 ; Endocarditis ; Endocarditis, Bacterial/complications ; Endocarditis, Bacterial/diagnosis ; Endocarditis, Bacterial/drug therapy ; Humans ; Male ; Middle Aged ; SARS-CoV-2 ; Staphylococcal Infections/complications ; Staphylococcal Infections/diagnosis ; Staphylococcal Infections/drug therapy ; Staphylococcus aureus
    Language English
    Publishing date 2021-08-03
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2021-242205
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Navigating Complex Diagnostics During COVID-19: Repeated Testing Unveils Infective Endocarditis in a 61-Year-Old Woman.

    Mine, Yuichiro / Miyagami, Taiju / Furuya, Satoshi / Kondo, Yusuke / Furusaka, Takayuki / Naito, Toshio

    The American journal of case reports

    2023  Volume 24, Page(s) e939793

    Abstract: ... to delays, especially amidst the complexities of the ongoing COVID-19 pandemic. CASE REPORT A 61-year-old ... like the COVID-19 pandemic. A single inconclusive test should not preclude a diagnosis, underscoring ... of suspicion and flexible diagnostic approach, particularly in high-risk patients and complex care environments ...

    Abstract BACKGROUND Infective endocarditis (IE), a systemic infection characterized by bacterial vegetative growths on heart valves and endothelium, often manifests variably and leads to severe complications, sometimes even death. Accurate and timely diagnosis is paramount, yet the variety of symptoms can lead to delays, especially amidst the complexities of the ongoing COVID-19 pandemic. CASE REPORT A 61-year-old woman with a history of mitral valve regurgitation was admitted after a month of low-grade fever, night sweats, and polyarthritis. Initial blood cultures and CT scans were inconclusive. Upon admission, clinical examination uncovered a heart murmur, leukocytosis, and elevated C-reactive protein levels. Further examination by another physician revealed conjunctival hemorrhage and Janeway lesions. Subsequent blood cultures tested positive for Streptococcus oralis, and transesophageal echocardiography revealed mitral valve prolapse with vegetation, leading to a diagnosis of IE. Following a 6-week course of ampicillin, the patient recovered successfully. CONCLUSIONS This case underlines the necessity of maintaining a high index of suspicion and flexible diagnostic approach, particularly in high-risk patients and complex care environments like the COVID-19 pandemic. A single inconclusive test should not preclude a diagnosis, underscoring the importance of repeated testing and comprehensive assessments in timely disease identification.
    MeSH term(s) Female ; Humans ; Middle Aged ; Pandemics ; COVID-19 ; Endocarditis, Bacterial/diagnosis ; Endocarditis/diagnosis ; Ampicillin ; COVID-19 Testing
    Chemical Substances Ampicillin (7C782967RD)
    Language English
    Publishing date 2023-07-13
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2517183-5
    ISSN 1941-5923 ; 1941-5923
    ISSN (online) 1941-5923
    ISSN 1941-5923
    DOI 10.12659/AJCR.939793
    Database MEDical Literature Analysis and Retrieval System OnLINE

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