Article: Presentation and Management of Cutaneous Manifestations of COVID-19.
Journal of drugs in dermatology : JDD
2020 Volume 20, Issue 1, Page(s) 76–83
Abstract: ... South America with positive COVID-19 PCR and/or serology presenting cutaneous manifestations were included ... at risk, and optimal disease management. While the COVID-19 illness is largely associated with respiratory ... and disease management were documented.: Results: Seven main types of cutaneous manifestations were ...
| Abstract | Introduction: The spread of the new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has instigated a fervent race of the medical community to identify its manifestations, the patients at risk, and optimal disease management. While the COVID-19 illness is largely associated with respiratory consequences, there is increased reporting of other organ-specific disease sequelae that include the skin. Objective: To identify, describe, and classify the main skin manifestations of COVID-19 and associated protocols for management. Methods: Forty-five patients from three clinical centers in North and South America with positive COVID-19 PCR and/or serology presenting cutaneous manifestations were included in this retrospective chart review. Medical history, biopsies, dermoscopy, laboratory findings, clinical photography, and disease management were documented. Results: Seven main types of cutaneous manifestations were identified: exanthema/molbilliform, urticaria, papular/pustular/vesicular, petechiae/purpura, livedo reticularis, chilblains, and alopecia. Histopathogical analysis from skin biopsies and/or dermoscopy highlighted an inflammatory or vascular pathophysiology depending on the type of manifestation. While the first three types of COVID-19 skin manifestations preceded or coincided with other symptoms such as anosmia, fever, chills, chilblains, and livedo were found in later disease stages. All cases had a positive resolution with appropriate treatment. Conclusions: Cutaneous symptoms are part of the COVID-19 disease spectrum. Early identification, diagnosis, and management through a multidisciplinary approach can facilitate safe disease resolution for patients. J Drugs Dermatol. 2021;20(1):76-83. doi:10.36849/JDD5676. |
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| MeSH term(s) | Adolescent ; Adult ; Aged ; COVID-19/diagnosis ; COVID-19/epidemiology ; COVID-19/therapy ; Child ; Child, Preschool ; Diagnosis, Differential ; Disease Management ; Female ; Humans ; Infant ; Male ; Middle Aged ; Retrospective Studies ; Skin Diseases/diagnosis ; Skin Diseases/epidemiology ; Skin Diseases/therapy ; Young Adult |
| Language | English |
| Publishing date | 2020-08-03 |
| Publishing country | United States |
| Document type | Journal Article ; Multicenter Study |
| ZDB-ID | 2145090-0 |
| ISSN | 1545-9616 |
| ISSN | 1545-9616 |
| DOI | 10.36849/JDD.5676 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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