Article ; Online: One year on: an updated systematic review of SARS-CoV-2, COVID-19 and audio-vestibular symptoms.
International journal of audiology
2021 Volume 60, Issue 12, Page(s) 935–945
Abstract: ... to provide a timely summary of evidence on SARS-CoV-2, COVID-19 and audio-vestibular symptoms.: Design ... Conclusion: There are multiple reports of audio-vestibular symptoms associated with COVID-19. However, there ... is a dearth of high-quality studies comparing COVID-19 cases and controls.: Review registration ...
| Abstract | Objective: The aim was to systematically review the literature to December 2020, in order to provide a timely summary of evidence on SARS-CoV-2, COVID-19 and audio-vestibular symptoms. Design: The protocol was registered in the International Prospective Register of Systematic Reviews. The methods were developed in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines. Risk of bias was assessed using the National Institutes of Heath quality assessment tools. Study sample: After rejecting 850 records, 28 case reports/series and 28 cross-sectional studies met the inclusion criteria. Results: There are multiple reports of hearing loss (e.g. sudden sensorineural), tinnitus and rotatory vertigo in adults having a wide range of COVID-19 symptom severity. The pooled estimate of prevalence based primarily on retrospective recall of symptoms, was 7.6% (CI: 2.5-15.1), 14.8% (CI: 6.3-26.1) and 7.2% (CI: 0.01-26.4), for hearing loss, tinnitus and rotatory vertigo, respectively. However, these could be an over-estimate because it was not always clear that studies report a change in symptom. Conclusion: There are multiple reports of audio-vestibular symptoms associated with COVID-19. However, there is a dearth of high-quality studies comparing COVID-19 cases and controls. Review registration: Prospective Register of Systematic Reviews (PROSPERO); registration number CRD42020227038). |
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| MeSH term(s) | Adult ; COVID-19 ; Cross-Sectional Studies ; Humans ; Retrospective Studies ; SARS-CoV-2 ; Vertigo/diagnosis ; Vertigo/epidemiology | |||||
| Language | English | |||||
| Publishing date | 2021-03-22 | |||||
| Publishing country | England | |||||
| Document type | Journal Article ; Research Support, Non-U.S. Gov't ; Systematic Review | |||||
| ZDB-ID | 2073098-6 | |||||
| ISSN | 1708-8186 ; 1499-2027 | |||||
| ISSN (online) | 1708-8186 | |||||
| ISSN | 1499-2027 | |||||
| DOI | 10.1080/14992027.2021.1896793 | |||||
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| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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