Article: HIGD1A-mediated dormancy and tumor survival.
Molecular & cellular oncology
2015 Volume 2, Issue 4, Page(s) e1030537
Abstract: ... modulates oxygen consumption and reactive oxygen species production to enable tumor cell survival ... Solid tumors contain regions of anoxia that are also glucose deprived. How cancer cells survive ... inducible gene domain family member 1 A (HIGD1A) via epigenetic mechanisms during glucose starvation ...
| Abstract | Solid tumors contain regions of anoxia that are also glucose deprived. How cancer cells survive such extreme conditions remains unclear. Here, we discuss our recent findings that regulation of hypoxia inducible gene domain family member 1 A (HIGD1A) via epigenetic mechanisms during glucose starvation modulates oxygen consumption and reactive oxygen species production to enable tumor cell survival through the activation of dormancy mechanisms. |
|---|---|
| Language | English |
| Publishing date | 2015-04-14 |
| Publishing country | United States |
| Document type | Journal Article |
| ISSN | 2372-3556 |
| ISSN | 2372-3556 |
| DOI | 10.1080/23723556.2015.1030537 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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