LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 2 of total 2

Search options

  1. Article ; Online: Mucocutaneous manifestations in children hospitalized with COVID-19.

    Andina-Martinez, David / Nieto-Moro, Montserrat / Alonso-Cadenas, Jose Antonio / Añon-Hidalgo, Juan / Hernandez-Martin, Angela / Perez-Suarez, Esther / Colmenero-Blanco, Isabel / Iglesias-Bouza, Maria Isabel / Cano-Fernandez, Julia / Mateos-Mayo, Ana / Torrelo, Antonio

    Journal of the American Academy of Dermatology

    2021  Volume 85, Issue 1, Page(s) 88–94

    Abstract: ... Children hospitalized with COVID-19 frequently had mucocutaneous involvement, with most symptoms fulfilling criteria ... on a series of 50 children hospitalized with COVID-19 between March 1, 2020, and November 30, 2020.: Results ... Background: Cutaneous manifestations in hospitalized children with SARS-CoV-2 have not been ...

    Abstract Background: Cutaneous manifestations in hospitalized children with SARS-CoV-2 have not been studied systematically.
    Objective: To describe the mucocutaneous involvement in pediatric patients with COVID-19 admitted to a pediatric institution in Madrid (Spain), located in a zone reporting among the highest prevalence of COVID-19 in Europe.
    Methods: A descriptive, analytical study was conducted on a series of 50 children hospitalized with COVID-19 between March 1, 2020, and November 30, 2020.
    Results: Twenty-one patients presented with mucocutaneous symptoms: 18 patients with macular and/or papular exanthem, 17 with conjunctival hyperemia, and 9 with red cracked lips or strawberry tongue. Eighteen patients fulfilled criteria for multisystem inflammatory syndrome in children. Patients with mucocutaneous involvement tended to be older and presented to the emergency department with poor general status and extreme tachycardia, higher C-reactive protein and D-dimer levels, and lower lymphocyte counts than patients without skin signs. Mucocutaneous manifestations pose a higher risk of admission to the pediatric intensive care unit (odds ratio, 10.24; 95% confidence interval, 2.23-46.88; P = .003).
    Conclusions: Children hospitalized with COVID-19 frequently had mucocutaneous involvement, with most symptoms fulfilling criteria for multisystem inflammatory syndrome in children. Patients with an exanthem or conjunctival hyperemia at admission have a higher probability of pediatric intensive care admission than patients without mucocutaneous symptoms.
    MeSH term(s) COVID-19/complications ; COVID-19/diagnosis ; Child ; Child, Preschool ; Female ; Hospitalization ; Humans ; Infant ; Male ; Mucous Membrane ; Retrospective Studies ; Skin Diseases/diagnosis ; Skin Diseases/etiology ; Systemic Inflammatory Response Syndrome/diagnosis
    Language English
    Publishing date 2021-04-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 603641-7
    ISSN 1097-6787 ; 0190-9622
    ISSN (online) 1097-6787
    ISSN 0190-9622
    DOI 10.1016/j.jaad.2021.03.083
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1540: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article ; Online: Mucocutaneous Manifestations of Multisystem Inflammatory Syndrome in Children During the COVID-19 Pandemic.

    Young, Trevor K / Shaw, Katharina S / Shah, Jinal K / Noor, Asif / Alperin, Risa A / Ratner, Adam J / Orlow, Seth J / Betensky, Rebecca A / Shust, Gail F / Kahn, Philip J / Oza, Vikash S

    JAMA dermatology

    2020  Volume 157, Issue 2, Page(s) 207–212

    Abstract: ... in children with MIS-C during the height of the coronavirus disease 2019 (COVID-19) pandemic in New York City ... with suspected MIS-C during the COVID-19 pandemic, a wide spectrum of mucocutaneous findings was identified ... in hospitalized children with multisystem inflammatory syndrome in children (MIS-C) or the temporal association ...

    Abstract Importance: To date, no study has characterized the mucocutaneous features seen in hospitalized children with multisystem inflammatory syndrome in children (MIS-C) or the temporal association of these findings with the onset of systemic symptoms.
    Objective: To describe the mucocutaneous findings seen in children with MIS-C during the height of the coronavirus disease 2019 (COVID-19) pandemic in New York City in 2020.
    Design, setting, and participants: A retrospective case series was conducted of 35 children admitted to 2 hospitals in New York City between April 1 and July 14, 2020, who met Centers for Disease Control and Prevention and/or epidemiologic criteria for MIS-C.
    Main outcomes and measures: Laboratory and clinical characteristics, with emphasis on mucocutaneous findings, of children who met criteria for MIS-C. The characterization of mucocutaneous features was verified by 2 board-certified pediatric dermatologists.
    Results: Twenty-five children (11 girls [44%]; median age, 3 years [range, 0.7-17 years]) were identified who met definitional criteria for MIS-C; an additional 10 children (5 girls [50%]; median age, 1.7 years [range, 0.2-15 years]) were included as probable MIS-C cases (patients met all criteria with the exception of laboratory test evidence of severe acute respiratory syndrome coronavirus 2 [SARS-CoV-2] infection or known exposure). The results of polymerase chain reaction tests for SARS-CoV-2 were positive for 10 patients (29%), and the results of SARS-CoV-2 immunoglobulin G tests were positive for 19 patients (54%). Of the 35 patients, 29 (83%) exhibited mucocutaneous changes, with conjunctival injection (n = 21), palmoplantar erythema (n = 18), lip hyperemia (n = 17), periorbital erythema and edema (n = 7), strawberry tongue (n = 8), and malar erythema (n = 6) being the most common findings. Recognition of mucocutaneous findings occurred a mean of 2.7 days (range, 1-7 days) after the onset of fever. The duration of mucocutaneous findings varied from hours to days (median duration, 5 days [range, 0-11 days]). Neither the presence nor absence of mucocutaneous findings was significantly associated with overall disease severity.
    Conclusions and relevance: In this case series of hospitalized children with suspected MIS-C during the COVID-19 pandemic, a wide spectrum of mucocutaneous findings was identified. Despite their protean and transient nature, these mucocutaneous features serve as important clues in the recognition of MIS-C.
    MeSH term(s) Adolescent ; COVID-19/complications ; Child ; Child, Preschool ; Female ; Humans ; Infant ; Male ; Mucous Membrane ; New York City ; Retrospective Studies ; Skin Diseases/etiology ; Systemic Inflammatory Response Syndrome/complications
    Language English
    Publishing date 2020-12-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2701761-8
    ISSN 2168-6084 ; 2168-6068
    ISSN (online) 2168-6084
    ISSN 2168-6068
    DOI 10.1001/jamadermatol.2020.4779
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Ui VI Zs.32: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top