Article: Immunosuppression minimization in kidney transplant recipients hospitalized for COVID-19.
2021 Volume 14, Issue 4, Page(s) 1229–1235
Abstract: Background: Immunosuppressed patients such as kidney transplant recipients (KTs) have increased ... that immunosuppression in KTs hospitalized due to COVID-19 could be safely minimized. ... of a cohort of 47 KTs admitted at two Spanish Kidney Transplant Units, who survived COVID-19. The impact ...
Abstract | Background: Immunosuppressed patients such as kidney transplant recipients (KTs) have increased mortality risk in the setting of coronavirus disease 2019 (COVID-19). The role and management of chronic immunosuppressive therapies during COVID-19 must be characterized. Methods: Herein, we report the follow-up of a cohort of 47 KTs admitted at two Spanish Kidney Transplant Units, who survived COVID-19. The impact of the management of immunosuppression during COVID-19 on graft function and immunologic events was evaluated. Results: At least one immunosuppressive agent was withdrawn in 83% of patients, with antimetabolites being the most frequent. Steroids were generally not stopped and the dose was even increased in 15% of patients as part of the treatment of COVID-19. Although immunosuppressive drugs were suspended during a median time of 17 days, no rejection episodes or Conclusions: Our observational study suggests that immunosuppression in KTs hospitalized due to COVID-19 could be safely minimized. |
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Language | English |
Publishing date | 2021-01-29 |
Publishing country | England |
Document type | Journal Article |
ZDB-ID | 2655800-2 |
ISSN | 2048-8513 ; 2048-8505 |
ISSN (online) | 2048-8513 |
ISSN | 2048-8505 |
DOI | 10.1093/ckj/sfab025 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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