Article ; Online: BRASH Syndrome with Hyperkalemia: An Under-Recognized Clinical Condition.
Methodist DeBakey cardiovascular journal
2020 Volume 16, Issue 3, Page(s) 241–244
Abstract: BRASH syndrome is characterized by bradycardia, renal failure, use of an atrioventricular nodal ... renal function to worsen, thereby perpetuating the cycle of BRASH syndrome. ... blocker (AVNB), shock, and hyperkalemia. These symptoms represent an ongoing vicious cycle in a patient ...
| Abstract | BRASH syndrome is characterized by bradycardia, renal failure, use of an atrioventricular nodal blocker (AVNB), shock, and hyperkalemia. These symptoms represent an ongoing vicious cycle in a patient with a low glomerular filtration rate taking an AVNB. Decreased clearance of the medication and hyperkalemia associated with renal failure synergize to cause bradycardia and hypoperfusion. This reaction causes renal function to worsen, thereby perpetuating the cycle of BRASH syndrome. |
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| MeSH term(s) | Antihypertensive Agents/adverse effects ; Atrioventricular Node/drug effects ; Atrioventricular Node/physiopathology ; Bradycardia/chemically induced ; Bradycardia/diagnosis ; Bradycardia/physiopathology ; Bradycardia/therapy ; Diltiazem/adverse effects ; Female ; Glomerular Filtration Rate ; Humans ; Hyperkalemia/diagnosis ; Hyperkalemia/etiology ; Hyperkalemia/physiopathology ; Hyperkalemia/therapy ; Kidney/physiopathology ; Middle Aged ; Renal Insufficiency, Chronic/complications ; Renal Insufficiency, Chronic/diagnosis ; Renal Insufficiency, Chronic/therapy ; Syndrome ; Treatment Outcome |
| Chemical Substances | Antihypertensive Agents ; Diltiazem (EE92BBP03H) |
| Language | English |
| Publishing date | 2020-10-24 |
| Publishing country | United States |
| Document type | Case Reports |
| ZDB-ID | 2544079-2 |
| ISSN | 1947-6108 ; 1947-6094 |
| ISSN (online) | 1947-6108 |
| ISSN | 1947-6094 |
| DOI | 10.14797/mdcj-16-3-241 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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