Article ; Online: Persistierende Beschwerden 6 Monate nach COVID-19 – Erfahrungen aus der COVID-19-Nachsorgeambulanz des Universitätsklinikums Freiburg.
Pneumologie (Stuttgart, Germany)
2022 Volume 76, Issue 10, Page(s) 679–688
Abstract: ... of persistently symptomatic patients presenting to our clinic at least 6 months after onset of acute COVID-19 ... Patients presenting 6 months after onset of acute COVID-19 suffer from a diverse spectrum of symptoms ... to the post-COVID clinic at the University Medical Center Freiburg.: Methods: Retrospective data analysis ...
| Title translation | Complaints and clinical findings six months after COVID-19: outpatient follow-up at the University Medical Center Freiburg. |
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| Abstract | Background: Increasing evidence suggests that some patients suffer from persistent symptoms for months after recovery from acute COVID-19. However, the clinical phenotype and its pathogenesis remain unclear. We here present data on complaints and results of a diagnostic workup of patients presenting to the post-COVID clinic at the University Medical Center Freiburg. Methods: Retrospective data analysis of persistently symptomatic patients presenting to our clinic at least 6 months after onset of acute COVID-19. All patients were assessed by a doctor and routine laboratory analysis was carried out. Quality of life was assessed using SF-36 questionnaire. In case of specific persisting symptoms, further organ-specific diagnostic evaluation was performed, and patients were referred to respective departments/specialists. Findings: 132 Patients (58 male, 74 female; mean age 53.8 years) presented to our clinic at least 6 months after COVID-19. 79 (60 %) had been treated as outpatients and 53 (40 %) as inpatients. Most common complaints were persistent fatigue (82 %) and dyspnea on exertion (61 %). Further common complaints were impairments of concentration (54 %), insomnia (43 %), and impairments of smell or taste (35 %). Quality of life was reduced in all sections of the SF-36 questionnaire, yielding a reduced working capacity. Significant pathological findings in laboratory, echocardiographic and radiological work-up were rare. Impairments in lung function tests were more common in previously hospitalized patients. Conclusion: Patients presenting 6 months after onset of acute COVID-19 suffer from a diverse spectrum of symptoms with impaired quality of life, also referred to as Long COVID or Post-Acute Sequelae of SARS-CoV-2 infection (PASC). Further research is needed to determine the frequency of these post-COVID syndromes and their pathogenesis, natural course and treatment options. Evaluation and management should be multi-disciplinary. |
| MeSH term(s) | Male ; Female ; Humans ; COVID-19 ; SARS-CoV-2 ; Outpatients ; Quality of Life ; Retrospective Studies ; Follow-Up Studies ; Academic Medical Centers |
| Language | German |
| Publishing date | 2022-10-18 |
| Publishing country | Germany |
| Document type | English Abstract ; Journal Article |
| ZDB-ID | 607630-0 |
| ISSN | 1438-8790 ; 0934-8387 |
| ISSN (online) | 1438-8790 |
| ISSN | 0934-8387 |
| DOI | 10.1055/a-1916-1405 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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