Article ; Online: COVID-19 and Candida duobushaemulonii superinfection: A case report.
2021 Volume 31, Issue 3, Page(s) 101168
Abstract: ... to COVID-19 infection and developed Candida duobushaemulonii fungemia after multiple courses of antibiotics ... patients is scarce, and nonexistent regarding Candida duobushaemulonii superinfections.: Case description ... broad-spectrum antibiotics. Data regarding multidrug resistant (MDR) Candida species in COVID-19 ...
Abstract | Introduction: Critically ill COVID-19 patients are at high risk for nosocomial bacterial and fungal infections due to several predisposing factors such as intensive care unit stay, mechanical ventilation, and broad-spectrum antibiotics. Data regarding multidrug resistant (MDR) Candida species in COVID-19 patients is scarce, and nonexistent regarding Candida duobushaemulonii superinfections. Case description: A 34-year-old male presented to our institution with acute respiratory distress syndrome (ARDS) due to COVID-19 infection and developed Candida duobushaemulonii fungemia after multiple courses of antibiotics and prolonged mechanical ventilation. He died after recurrent pneumothorax led to respiratory failure and cardiac arrest. Discussion: Bacterial and fungal infections are common complications of viral pneumonia in critically ill patients. Data regarding these infections in COVID-19 patients has been poorly studied with only a few cases reporting secondary infection, mostly without identifying specific pathogens. Prolonged hospital stays, invasive interventions (central venous catheter, mechanical ventilation), and the use of broad-spectrum antibiotics in COVID-19 infections could carry a high risk of bacterial and/or fungal superinfections. Conclusion: Strategies to improve outcome in COVID-19 ICU patients should include early recognition of candidemia and appropriate antifungal therapy. |
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MeSH term(s) | Adult ; Antifungal Agents/therapeutic use ; COVID-19/complications ; Candida ; Candidemia/complications ; Candidemia/drug therapy ; Fatal Outcome ; Humans ; Male ; Respiration, Artificial ; Respiratory Distress Syndrome ; Saccharomycetales ; Superinfection/complications ; Superinfection/drug therapy | |||||
Chemical Substances | Antifungal Agents | |||||
Language | English | |||||
Publishing date | 2021-06-16 | |||||
Publishing country | France | |||||
Document type | Case Reports ; Journal Article | |||||
ZDB-ID | 1067006-3 | |||||
ISSN | 1773-0449 ; 1156-5233 | |||||
ISSN (online) | 1773-0449 | |||||
ISSN | 1156-5233 | |||||
DOI | 10.1016/j.mycmed.2021.101168 | |||||
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Database | MEDical Literature Analysis and Retrieval System OnLINE |
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