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  1. Article ; Online: Understanding Obesity: The Role of Adipose Tissue Microenvironment and the Gut Microbiome.

    Awan, Nusrat M / Meurling, Imran J / O'Shea, Donal

    Saudi journal of medicine & medical sciences

    2020  Volume 9, Issue 1, Page(s) 10–15

    Abstract: ... on the immune system and its interaction with both the adipose tissue organ and the gut microbiome ... As our understanding of the causes and effects of obesity improves, opportunities should emerge, underpinned ... In this article, we review advances in our understanding of the pathophysiology underlying obesity, with a focus ...

    Abstract The prevalence of obesity has more than doubled globally over the past few decades, with a 12-fold rise in extreme levels. Obesity, with its multiple complications, remains a major ongoing challenge for health-care professionals, as highlighted by the COVID-19 pandemic, where people with obesity had poorer outcomes. In this article, we review advances in our understanding of the pathophysiology underlying obesity, with a focus on the immune system and its interaction with both the adipose tissue organ and the gut microbiome. As our understanding of the causes and effects of obesity improves, opportunities should emerge, underpinned by rigorous laboratory and clinical research, to both better prevent and treat this global epidemic.
    Language English
    Publishing date 2020-12-26
    Publishing country India
    Document type Journal Article ; Review
    ZDB-ID 2734896-9
    ISSN 2321-4856 ; 1658-631X
    ISSN (online) 2321-4856
    ISSN 1658-631X
    DOI 10.4103/sjmms.sjmms_561_20
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Understanding Obesity

    Nusrat M Awan / Imran J Meurling / Donal O'Shea

    Saudi Journal of Medicine and Medical Sciences, Vol 9, Iss 1, Pp 10-

    The Role of Adipose Tissue Microenvironment and the Gut Microbiome

    2021  Volume 15

    Abstract: ... on the immune system and its interaction with both the adipose tissue organ and the gut microbiome ... As our understanding of the causes and effects of obesity improves, opportunities should emerge, underpinned ... In this article, we review advances in our understanding of the pathophysiology underlying obesity, with a focus ...

    Abstract The prevalence of obesity has more than doubled globally over the past few decades, with a 12-fold rise in extreme levels. Obesity, with its multiple complications, remains a major ongoing challenge for health-care professionals, as highlighted by the COVID-19 pandemic, where people with obesity had poorer outcomes. In this article, we review advances in our understanding of the pathophysiology underlying obesity, with a focus on the immune system and its interaction with both the adipose tissue organ and the gut microbiome. As our understanding of the causes and effects of obesity improves, opportunities should emerge, underpinned by rigorous laboratory and clinical research, to both better prevent and treat this global epidemic.
    Keywords adipose tissue ; gut microbiome ; immune cells ; inflammation ; obesity ; Medicine ; R
    Language English
    Publishing date 2021-01-01T00:00:00Z
    Publisher Wolters Kluwer Medknow Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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