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  1. Article ; Online: Multisystem inflammatory syndrome associated with SARS-CoV-2 in a Japanese girl.

    Baba, Tomoaki / Maruyama, Tomoko / Katsuragi, Shinichi / Maeda, Kyohei / Kogaki, Shigetoyo

    Pediatrics international : official journal of the Japan Pediatric Society

    2021  Volume 64, Issue 1, Page(s) e14704

    MeSH term(s) COVID-19 ; Female ; Humans ; Japan ; Mucocutaneous Lymph Node Syndrome ; SARS-CoV-2
    Language English
    Publishing date 2021-05-19
    Publishing country Australia
    Document type Journal Article ; Comment
    ZDB-ID 1470376-2
    ISSN 1442-200X ; 1328-8067
    ISSN (online) 1442-200X
    ISSN 1328-8067
    DOI 10.1111/ped.14704
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    ab Jg. 2022: Lesesaal (EG)

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  2. Article: Case Report: A case of multisystem inflammatory syndrome in an 11-year-old female after COVID-19 inactivated vaccine.

    Saeed, Saboor / Cao, Jianqing / Xu, Jinjiao / Zhang, Yi / Zheng, Xuyang / Jiang, Liya / Jiang, Chunming / Zhang, Xinjuan

    Frontiers in pediatrics

    2023  Volume 11, Page(s) 1068301

    Abstract: ... inflammatory, multisystem syndrome temporally associated with SARS-CoV-2, is a rare but serious complication ... of SARS-CoV-2 infection in children that typically occurs 2-6 weeks after SARS-CoV-2 infection ... her 2nd SARS-CoV-2 inactivated vaccination dose five days before hospital admission. On day 3 & 4 ...

    Abstract Background: Multisystem inflammatory syndrome in children (MIS-C), also known as pediatric inflammatory, multisystem syndrome temporally associated with SARS-CoV-2, is a rare but serious complication of SARS-CoV-2 infection in children that typically occurs 2-6 weeks after SARS-CoV-2 infection. The pathophysiology of MIS-C is unknown. MIS-C, first recognized in April 2020, is characterized by fever, systemic inflammation, and multi-system organ involvement. Post-vaccination adverse effects have increased with COVID-19 vaccinations, and MIS linked to immunization with COVID-19 vaccines has also been observed.
    Case report: An 11-year-old Chinese girl presented with a high-grade fever, rash, and dry cough for 2 days. She had her 2nd SARS-CoV-2 inactivated vaccination dose five days before hospital admission. On day 3 & 4, she experienced bilateral conjunctivitis, hypotension (66/47 mmHg), and a high CRP level. She was diagnosed with MIS-C. The patient's condition deteriorated rapidly, necessitating intensive care unit admission. The patient's symptoms improved after intravenous immunoglobulin, methylprednisolone, and oral aspirin therapy. She was discharged from the hospital after 16 days as her general condition, and laboratory biomarkers returned to normal.
    Conclusion: Inactivated Covid-19 vaccination might trigger MIS-C. Further research is needed to evaluate whether a correlation exists between COVID-19 vaccination and MIS-C development.
    Language English
    Publishing date 2023-02-14
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2711999-3
    ISSN 2296-2360
    ISSN 2296-2360
    DOI 10.3389/fped.2023.1068301
    Database MEDical Literature Analysis and Retrieval System OnLINE

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