Article ; Online: Joint Investigation of 2-Month Post-diagnosis IgG Antibody Levels and Psychological Measures for Assessing Longer Term Multi-Faceted Recovery Among COVID-19 Cases in Northern Cyprus.
2021 Volume 8, Page(s) 590096
Abstract: ... of the outbreak in Northern Cyprus. Associations of antibody titers and psychological survey measures ... effects of the COVID-19 infection and the complete recovery is still scarce. With regards to long-term consequences ... address the physiological and psychological effects of COVID-19 among the cases. ...
| Abstract | Following the outbreak of COVID-19, multidisciplinary research focusing on the long-term effects of the COVID-19 infection and the complete recovery is still scarce. With regards to long-term consequences, biomarkers of physiological effects as well as the psychological experiences are of significant importance for comprehensively understanding the complete COVID-19 recovery. The present research surveys the IgG antibody titers and the impact of COVID-19 as a traumatic experience in the aftermath of the active infection period, around 2 months after diagnosis, in a subset of COVID-19 patients from the first wave (March-April 2020) of the outbreak in Northern Cyprus. Associations of antibody titers and psychological survey measures with baseline characteristics and disease severity were explored, and correlations among various measures were evaluated. Of the 47 serology tests conducted for presence of IgG antibodies, 39 (83%) were positive. We identified trends demonstrating individuals experiencing severe or critical COVID-19 disease and/or those with comorbidities are more heavily impacted both physiologically and mentally, with higher IgG titers and negative psychological experience compared to those with milder disease and without comorbidities. We also observed that more than half of the COVID-19 cases had negative psychological experiences, being subjected to discrimination and verbal harassment/insult, by family/friends. In summary, as the first study co-evaluating immune response together with mental status in COVID-19, our findings suggest that further multidisciplinary research in larger sample populations as well as community intervention plans are needed to holistically address the physiological and psychological effects of COVID-19 among the cases. |
|---|---|
| MeSH term(s) | Adolescent ; Adult ; Antibodies, Viral/blood ; Biomarkers/blood ; COVID-19/immunology ; COVID-19/psychology ; COVID-19 Serological Testing ; Cyprus ; Female ; Follow-Up Studies ; Humans ; Immunoglobulin G/blood ; Male ; Middle Aged ; Psychological Tests ; SARS-CoV-2/immunology |
| Chemical Substances | Antibodies, Viral ; Biomarkers ; Immunoglobulin G |
| Language | English |
| Publishing date | 2021-02-02 |
| Publishing country | Switzerland |
| Document type | Journal Article ; Research Support, Non-U.S. Gov't |
| ZDB-ID | 2711781-9 |
| ISSN | 2296-2565 ; 2296-2565 |
| ISSN (online) | 2296-2565 |
| ISSN | 2296-2565 |
| DOI | 10.3389/fpubh.2020.590096 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
More links
Kategorien
Order via subito
This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.