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  1. Article: Síndrome de Guillain-Barré como forma de presentación de la infección por SARS-CoV-2./ Síndrome de Guillain-Barré como forma de presentación de la infección por SARS-CoV-2./ Guillain-Barré syndrome as the first manifestation of SARS-CoV-2 infection

    Barrachina-Esteve, O / Palau Domínguez, A / Hidalgo-Torrico, I / Viguera Martínez, M L

    Neurologia (Barc., Ed. impr.)

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #654380
    Database COVID19

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  2. Article ; Online: Síndrome de Guillain-Barré como forma de presentación de la infección por SARS-CoV-2.

    Barrachina-Esteve, O / Palau Domínguez, A / Hidalgo-Torrico, I / Viguera Martínez, M L

    Neurologia (Barcelona, Spain)

    2020  Volume 35, Issue 9, Page(s) 710–712

    Title translation Guillain-Barré syndrome as the first manifestation of SARS-CoV-2 infection.
    Language Spanish
    Publishing date 2020-07-16
    Publishing country Spain
    Document type Journal Article
    ZDB-ID 1056021-x
    ISSN 1578-1968 ; 0213-4853
    ISSN (online) 1578-1968
    ISSN 0213-4853
    DOI 10.1016/j.nrl.2020.07.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 3093: Show issues Location:
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  3. Article ; Online: Síndrome de Guillain-Barré como forma de presentación de la infección por SARS-CoV-2.

    Barrachina-Esteve, O / Palau Domínguez, A / Hidalgo-Torrico, I / Viguera Martínez, M L

    Neurologia (Barcelona, Spain)

    2020  Volume 35, Issue 9, Page(s) 710–712

    Title translation Guillain-Barré syndrome as the first manifestation of SARS-CoV-2 infection.
    MeSH term(s) Azithromycin/therapeutic use ; COVID-19/complications ; COVID-19/diagnosis ; COVID-19/drug therapy ; COVID-19/physiopathology ; Ceftriaxone/therapeutic use ; Drug Combinations ; Female ; Guillain-Barre Syndrome/physiopathology ; Guillain-Barre Syndrome/virology ; Humans ; Hydroxychloroquine/therapeutic use ; Lopinavir/therapeutic use ; Male ; Middle Aged ; Pandemics ; Ritonavir/therapeutic use ; SARS-CoV-2/drug effects
    Chemical Substances Drug Combinations ; lopinavir-ritonavir drug combination ; Lopinavir (2494G1JF75) ; Hydroxychloroquine (4QWG6N8QKH) ; Ceftriaxone (75J73V1629) ; Azithromycin (83905-01-5) ; Ritonavir (O3J8G9O825)
    Keywords covid19
    Language Spanish
    Publishing date 2020-07-16
    Publishing country Spain
    Document type Case Reports ; Letter
    ZDB-ID 2654369-2
    ISSN 2173-5808 ; 2173-5808
    ISSN (online) 2173-5808
    ISSN 2173-5808
    DOI 10.1016/j.nrl.2020.07.001
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  4. Article ; Online: Guillain-Barré Syndrome Associated with SARS-CoV-2 Infection in a Pediatric Patient.

    Frank, Carlos Henrique Michiles / Almeida, Taynná Vernalha Rocha / Marques, Elyana Almeida / de Sousa Monteiro, Quezia / Feitoza, Pablo Vinícius Silveira / Borba, Mayla Gabriela Silva / Vasconcelos, Heline Lira / de Souza Bastos, Michele / Lacerda, Marcus Vinicius Guimarães

    Journal of tropical pediatrics

    2020  Volume 67, Issue 3

    Abstract: ... reported pediatric case of SARS-CoV-2 infection associated with GBS. Evidence reveals that SARS-CoV-2 ... of Guillain-Barré syndrome. No cases involving young patients have been presented to date. Therefore, this is the first ... positive for SARS-CoV-2. The blood tests, cerebral spinal fluid (CSF) analysis and CSF aerobic culture ...

    Abstract We report the case of a 15-year-old male patient presenting frontal headaches with retro-orbital pain accompanied by fever evolving to weakness and pain of the lower limbs, which ascended to upper limbs. A COVID-19 rapid test (IgG and IgM) and nasopharyngeal swab polymerase chain reaction (PCR) was positive for SARS-CoV-2. The blood tests, cerebral spinal fluid (CSF) analysis and CSF aerobic culture revealed no abnormalities. PCR testing of the CSF was negative for the most prevalent etiologies as well as for SARS-CoV-2. Electroneurography study was compatible with the acute motor axonal neuropathy variant of Guillain-Barré syndrome. No cases involving young patients have been presented to date. Therefore, this is the first reported pediatric case of SARS-CoV-2 infection associated with GBS. Evidence reveals that SARS-CoV-2 infection is not limited to the respiratory tract. Neurotropism could explain this important neurologic manifestation of COVID-19 in children.
    MeSH term(s) Adolescent ; COVID-19 ; Child ; Guillain-Barre Syndrome/diagnosis ; Headache ; Humans ; Male ; Pain ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-07-09
    Publishing country England
    Document type Case Reports ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 800065-7
    ISSN 1465-3664 ; 0449-3281 ; 0142-6338
    ISSN (online) 1465-3664
    ISSN 0449-3281 ; 0142-6338
    DOI 10.1093/tropej/fmaa044
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    Zs.A 932: Show issues Location:
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  5. Article ; Online: Guillain–Barré syndrome as the first manifestation of SARS-CoV-2 infection

    Barrachina-Esteve, O. / Palau Domínguez, A. / Hidalgo Torrico, I. / Viguera Martinez, M.L.

    Neurología (English Edition) ; ISSN 2173-5808

    2020  

    Keywords covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    DOI 10.1016/j.nrleng.2020.07.002
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article: Guillain-Barre Syndrome Associated with SARS-CoV-2 Infection in a Pediatric Patient

    Frank, C. H. M. / Almeida, T. V. R. / Marques, E. A. / de Sousa Monteiro, Q. / Feitoza, P. V. S. / Borba, M. G. S. / Vasconcelos, H. L. / de Souza Bastos, M. / Lacerda, M. V. G.

    Journal of tropical pediatrics

    Abstract: ... reported pediatric case of SARS-CoV-2 infection associated with GBS Evidence reveals that SARS-CoV-2 ... of Guillain-Barre syndrome No cases involving young patients have been presented to date Therefore, this is the first ... positive for SARS-CoV-2 The blood tests, cerebral spinal fluid (CSF) analysis and CSF aerobic culture ...

    Abstract We report the case of a 15-year-old male patient presenting frontal headaches with retro-orbital pain accompanied by fever evolving to weakness and pain of the lower limbs, which ascended to upper limbs A COVID-19 rapid test (IgG and IgM) and nasopharyngeal swab polymerase chain reaction (PCR) was positive for SARS-CoV-2 The blood tests, cerebral spinal fluid (CSF) analysis and CSF aerobic culture revealed no abnormalities PCR testing of the CSF was negative for the most prevalent etiologies as well as for SARS-CoV-2 Electroneurography study was compatible with the acute motor axonal neuropathy variant of Guillain-Barre syndrome No cases involving young patients have been presented to date Therefore, this is the first reported pediatric case of SARS-CoV-2 infection associated with GBS Evidence reveals that SARS-CoV-2 infection is not limited to the respiratory tract Neurotropism could explain this important neurologic manifestation of COVID-19 in children Copyright © The Author(s) [2020] Published by Oxford University Press All rights reserved For permissions, please email: journals permissions@oup com
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #656391
    Database COVID19

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  8. Article ; Online: Guillain-Barré syndrome as a parainfectious manifestation of SARS-CoV-2 infection: A case series.

    Abolmaali, Meysam / Heidari, Matineh / Zeinali, Marjan / Moghaddam, Parichehr / Ramezani Ghamsari, Mona / Jamshidi Makiani, Mahin / Mirzaasgari, Zahra

    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia

    2020  Volume 83, Page(s) 119–122

    Abstract: The global SARS-CoV-2 pandemic posed an unprecedented challenge to almost all fields of medicine ... to severe autonomic dysfunction. We suggest SARS-CoV-2 might be associated with rather a severe, rapidly ... conditions will help clinicians to become more confident in managing this disease. Guillain-Barre Syndrome ...

    Abstract The global SARS-CoV-2 pandemic posed an unprecedented challenge to almost all fields of medicine and Neurology is not an exception. Collecting information about its complications and related conditions will help clinicians to become more confident in managing this disease. Guillain-Barre Syndrome (GBS) is mostly described as a post-infectious phenomenon and its occurrence during acute phase of illness is of interest. GBS has recently been reported during the active phase of COVID-19 for the first time. Severity and fast progression of GBS associated with COVID-19 have also been shown in recent studies. Here we report three cases of GBS during the active phase of COVID-19 with severe symptoms and fast progression to quadriplegia and facial diplegia over 2 days, which led to death in one case due to severe autonomic dysfunction. We suggest SARS-CoV-2 might be associated with rather a severe, rapidly progressive and life-threatening phenotype of GBS.
    MeSH term(s) Aged, 80 and over ; COVID-19/complications ; Disease Progression ; Facial Paralysis/etiology ; Fatal Outcome ; Female ; Guillain-Barre Syndrome/etiology ; Humans ; Male ; Middle Aged ; Neural Conduction ; Neurologic Examination ; Quadriplegia/etiology ; Treatment Outcome
    Language English
    Publishing date 2020-11-14
    Publishing country Scotland
    Document type Case Reports ; Journal Article
    ZDB-ID 1193674-5
    ISSN 1532-2653 ; 0967-5868
    ISSN (online) 1532-2653
    ISSN 0967-5868
    DOI 10.1016/j.jocn.2020.11.013
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    Zs.A 3999: Show issues Location:
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  9. Article ; Online: Guillain-Barré syndrome: The first documented COVID-19-triggered autoimmune neurologic disease: More to come with myositis in the offing.

    Dalakas, Marinos C

    Neurology(R) neuroimmunology & neuroinflammation

    2020  Volume 7, Issue 5

    Abstract: ... disease-like GBS, encephalomyelitis or myositis-even without systemic symptoms, may represent the first ... enhancing early diagnostic suspicion. In Miller-Fisher Syndrome, ganglioside antibodies against GD1b ... manifestation of COVID-19. Anosmia, ageusia, other cranial neuropathies and lymphocytopenia are red flags ...

    Abstract Objective: To present the COVID-19-associated GBS, the prototypic viral-triggered autoimmune disease, in the context of other emerging COVID-19-triggered autoimmunities, and discuss potential concerns with ongoing neuroimmunotherapies.
    Methods: Eleven GBS cases in four key COVID-19 hotspots are discussed regarding presenting symptoms, response to therapies and cross-reactivity of COVID spike proteins with nerve glycolipids. Emerging cases of COVID-19-triggered autoimmune necrotizing myositis (NAM) and encephalopathies are also reviewed in the context of viral invasion, autoimmunity and ongoing immunotherapies.
    Results: Collective data indicate that in this pandemic any patient presenting with an acute paralytic disease-like GBS, encephalomyelitis or myositis-even without systemic symptoms, may represent the first manifestation of COVID-19. Anosmia, ageusia, other cranial neuropathies and lymphocytopenia are red flags enhancing early diagnostic suspicion. In Miller-Fisher Syndrome, ganglioside antibodies against GD1b, instead of QG1b, were found; because the COVID-19 spike protein also binds to sialic acid-containing glycoproteins for cell-entry and anti-GD1b antibodies typically cause ataxic neuropathy, cross-reactivity between COVID-19-bearing gangliosides and peripheral nerve glycolipids was addressed. Elevated Creatine Kinase (>10,000) is reported in 10% of COVID-19-infected patients; two such patients presented with painful muscle weakness responding to IVIg indicating that COVID-19-triggered NAM is an overlooked entity. Cases of acute necrotizing brainstem encephalitis, cranial neuropathies with leptomeningeal enhancement, and tumefactive postgadolinium-enhanced demyelinating lesions are now emerging with the need to explore neuroinvasion and autoimmunity. Concerns for modifications-if any-of chronic immunotherapies with steroids, mycophenolate, azathioprine, IVIg, and anti-B-cell agents were addressed; the role of complement in innate immunity to viral responses and anti-complement therapeutics (i.e. eculizumab) were reviewed.
    Conclusions: Emerging data indicate that COVID-19 can trigger not only GBS but other autoimmune neurological diseases necessitating vigilance for early diagnosis and therapy initiation. Although COVID-19 infection, like most other viruses, can potentially worsen patients with pre-existing autoimmunity, there is no evidence that patients with autoimmune neurological diseases stable on common immunotherapies are facing increased risks of infection.
    MeSH term(s) Aged ; Aged, 80 and over ; Autoimmune Diseases of the Nervous System/diagnosis ; Autoimmune Diseases of the Nervous System/etiology ; Autoimmune Diseases of the Nervous System/immunology ; Betacoronavirus/immunology ; COVID-19 ; Coronavirus Infections/complications ; Coronavirus Infections/diagnosis ; Coronavirus Infections/immunology ; Female ; Guillain-Barre Syndrome/diagnosis ; Guillain-Barre Syndrome/etiology ; Guillain-Barre Syndrome/immunology ; Humans ; Male ; Myositis/diagnosis ; Myositis/etiology ; Myositis/immunology ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/immunology ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-06-09
    Publishing country United States
    Document type Case Reports ; Journal Article ; Review
    ZDB-ID 2767740-0
    ISSN 2332-7812 ; 2332-7812
    ISSN (online) 2332-7812
    ISSN 2332-7812
    DOI 10.1212/NXI.0000000000000781
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Concurrent Longitudinally Extensive Transverse Myelitis and Guillain-Barré Syndrome in a Child Secondary to COVID-19 Infection: A Severe Neuroimmunologic Complication of COVID-19.

    Khera, Daisy / Didel, Siyaram / Panda, Samhita / Tiwari, Sarbesh / Singh, Kuldeep

    The Pediatric infectious disease journal

    2021  Volume 40, Issue 6, Page(s) e236–e239

    Abstract: ... Guillain-Barré Syndrome (GBS). She failed to respond to immune suppressive therapy and needed plasma exchange for recovery ... This is probably the first pediatric case with concurrent GBS and LETM secondary to COVID-19 infection. ... Neurologic manifestation of coronavirus disease 2019 (COVID-19) in children is evolving with time ...

    Abstract Neurologic manifestation of coronavirus disease 2019 (COVID-19) in children is evolving with time. We are reporting a young girl who presented to us with acute febrile illness followed by acute onset severe flaccid paralysis requiring prolonged intensive care unit stay and ventilator support. She was evaluated extensively and found to be positive for COVID serology, and neuroimaging revealed features of longitudinally extensive transverse myelitis (LETM) with enhancing cauda equina nerve roots, suggesting Guillain-Barré Syndrome (GBS). She failed to respond to immune suppressive therapy and needed plasma exchange for recovery. Like other common viral illnesses, COVID-19 can also act as a trigger for GBS-like illness and LETM, and we need to suspect these diagnoses in the cases with COVID-19 infection in compatible cases. This is probably the first pediatric case with concurrent GBS and LETM secondary to COVID-19 infection.
    MeSH term(s) COVID-19/complications ; COVID-19/diagnosis ; COVID-19/immunology ; COVID-19 Serological Testing ; Child ; Female ; Guillain-Barre Syndrome/immunology ; Guillain-Barre Syndrome/virology ; Humans ; Myelitis, Transverse/immunology ; SARS-CoV-2/isolation & purification
    Language English
    Publishing date 2021-04-23
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 392481-6
    ISSN 1532-0987 ; 0891-3668
    ISSN (online) 1532-0987
    ISSN 0891-3668
    DOI 10.1097/INF.0000000000003124
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    Zs.A 1852: Show issues Location:
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