Article ; Online: Cryptic transmission of SARS-CoV-2 in Washington state.
2020 Volume 370, Issue 6516, Page(s) 571–575
Abstract: ... the reconstruction of its transmission history, although this is contingent on sampling. We analyzed 453 SARS-CoV-2 ... in the United States. We find that most SARS-CoV-2 infections sampled during this time derive from a single ... genomes collected between 20 February and 15 March 2020 from infected patients in Washington state ...
| Abstract | After its emergence in Wuhan, China, in late November or early December 2019, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus rapidly spread globally. Genome sequencing of SARS-CoV-2 allows the reconstruction of its transmission history, although this is contingent on sampling. We analyzed 453 SARS-CoV-2 genomes collected between 20 February and 15 March 2020 from infected patients in Washington state in the United States. We find that most SARS-CoV-2 infections sampled during this time derive from a single introduction in late January or early February 2020, which subsequently spread locally before active community surveillance was implemented. |
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| MeSH term(s) | Bayes Theorem ; Betacoronavirus/genetics ; COVID-19 ; Coronavirus Infections/epidemiology ; Coronavirus Infections/transmission ; Genome, Viral ; Humans ; Likelihood Functions ; Pandemics ; Phylogeny ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/transmission ; SARS-CoV-2 ; Washington/epidemiology |
| Keywords | covid19 |
| Language | English |
| Publishing date | 2020-09-10 |
| Publishing country | United States |
| Document type | Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't |
| ZDB-ID | 128410-1 |
| ISSN | 1095-9203 ; 0036-8075 |
| ISSN (online) | 1095-9203 |
| ISSN | 0036-8075 |
| DOI | 10.1126/science.abc0523 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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