Article ; Online: Perceived versus proven SARS-CoV-2-specific immune responses in health-care professionals.
2020 Volume 48, Issue 4, Page(s) 631–634
Abstract: ... at a university hospital with weekly SARS-CoV-2-specific serology (IgA/IgG). Study participants estimated their personal ... in the health-care system. The COVID-19 Contact (CoCo) Study follows 217 frontline health-care professionals ... IgG testing of health-care professionals may aid in directing resources for protective measures and ...
| Abstract | There have been concerns about high rates of thus far undiagnosed SARS-CoV-2 infections in the health-care system. The COVID-19 Contact (CoCo) Study follows 217 frontline health-care professionals at a university hospital with weekly SARS-CoV-2-specific serology (IgA/IgG). Study participants estimated their personal likelihood of having had a SARS-CoV-2 infection with a mean of 21% [median 15%, interquartile range (IQR) 5-30%]. In contrast, anti-SARS-CoV-2 IgG prevalence was about 1-2% at baseline. Regular anti-SARS-CoV-2 IgG testing of health-care professionals may aid in directing resources for protective measures and care of COVID-19 patients in the long run. |
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| MeSH term(s) | Adolescent ; Adult ; Aged ; Antibodies, Viral/blood ; Betacoronavirus ; COVID-19 ; Coronavirus Infections/diagnosis ; Coronavirus Infections/immunology ; Female ; Germany ; Health Personnel ; Hospitals, University ; Humans ; Immunoglobulin A/blood ; Immunoglobulin G/blood ; Male ; Middle Aged ; Pandemics ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/immunology ; Prevalence ; SARS-CoV-2 ; Seroepidemiologic Studies ; Serologic Tests ; Young Adult |
| Chemical Substances | Antibodies, Viral ; Immunoglobulin A ; Immunoglobulin G |
| Keywords | covid19 |
| Language | English |
| Publishing date | 2020-06-10 |
| Publishing country | Germany |
| Document type | Journal Article |
| ZDB-ID | 185104-4 |
| ISSN | 1439-0973 ; 0300-8126 ; 0173-2129 |
| ISSN (online) | 1439-0973 |
| ISSN | 0300-8126 ; 0173-2129 |
| DOI | 10.1007/s15010-020-01461-0 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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