Article ; Online: Intracranial microhemorrhages in the setting of COVID-19: what we know so far.
2021 Volume 34, Issue 5, Page(s) 435–439
Abstract: ... studies on intracranial microhemorrhages in the setting of COVID-19 were searched on PubMed, Google ... on magnetic resonance imaging in patients with COVID-19. If multiple patients were described, only patients with intracranial ... Conclusions: Intracranial microbleeds are a well-documented finding in patients with severe COVID-19, and are ...
| Abstract | Background: Diffuse intracranial susceptibility abnormalities have recently been described among patients with coronavirus disease 2019 (COVID-19), although prior studies have consisted of case reports and/or series. This brief literature review seeks to compile and catalogue the available data to elucidate characteristic features of such findings. Materials and methods: Scientific articles and studies on intracranial microhemorrhages in the setting of COVID-19 were searched on PubMed, Google Scholar, and the Cochrane Library. Included studies described intracranial microbleed(s) on magnetic resonance imaging in patients with COVID-19. If multiple patients were described, only patients with intracranial microhemorrhage on magnetic resonance imaging were included for analysis. Patient demographics, severity of illness (e.g. intensive care unit admission and/or intubation), time from diagnosis of COVID-19 to magnetic resonance imaging, and location(s) of any observed microhemorrhages were noted. Results: A total of 39 patients with suspected intracranial microhemorrhages have been described in prior studies. The average age of patients was 64.7 years; 21.9% were women. The average time between COVID-19 diagnosis and magnetic resonance imaging was 31.7 days. All patients in the cohort were admitted to critical care and were either intubated or treated with extracorporeal membrane oxygenation during their clinical course. Microhemorrhages were most commonly located in the subcortical/juxtacortical white matter and corpus callosum. Conclusions: Intracranial microbleeds are a well-documented finding in patients with severe COVID-19, and are most commonly callosal and subcortical/juxtacortical in location. |
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| MeSH term(s) | COVID-19/complications ; COVID-19/epidemiology ; COVID-19 Testing ; Disease Susceptibility ; Humans ; Intracranial Hemorrhages/epidemiology ; Intracranial Hemorrhages/etiology ; Magnetic Resonance Imaging ; Neuroimaging | |||||
| Language | English | |||||
| Publishing date | 2021-03-26 | |||||
| Publishing country | United States | |||||
| Document type | Journal Article ; Review | |||||
| ZDB-ID | 2257770-1 | |||||
| ISSN | 2385-1996 ; 1971-4009 ; 1120-9976 | |||||
| ISSN (online) | 2385-1996 | |||||
| ISSN | 1971-4009 ; 1120-9976 | |||||
| DOI | 10.1177/19714009211004144 | |||||
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| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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