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  1. Article: Exploring AyuGenomics approach for understanding COVID-19 predisposition and progression.

    Bhat, Vedika / Borse, Swapnil / Chavan-Gautam, Preeti / Joshi, Kalpana

    Journal of Ayurveda and integrative medicine

    2021  Volume 13, Issue 1, Page(s) 100463

    Abstract: Recent reports on COVID-19 suggest that, the susceptibility to COVID-19 infection and ... its progression have a genetic predisposition. Majorly associated genetic variants are found in human leukocyte ...

    Abstract Recent reports on COVID-19 suggest that, the susceptibility to COVID-19 infection and its progression have a genetic predisposition. Majorly associated genetic variants are found in human leukocyte antigen (HLA), angiotensin convertase enzyme (ACE; rs1799752: ACE2; rs73635825
    Language English
    Publishing date 2021-06-17
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 0975-9476
    ISSN 0975-9476
    DOI 10.1016/j.jaim.2021.06.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Exploring AyuGenomics approach for understanding COVID-19 predisposition and progression

    Vedika Bhat / Swapnil Borse / Preeti Chavan-Gautam / Kalpana Joshi

    Journal of Ayurveda and Integrative Medicine, Vol 13, Iss 1, Pp 100463- (2022)

    2022  

    Abstract: Recent reports on COVID-19 suggest that, the susceptibility to COVID-19 infection and ... strategies for management of COVID-19 based on differences in Prakriti, immune response, and drug response ... 19 prone and resistant populations. ...

    Abstract Recent reports on COVID-19 suggest that, the susceptibility to COVID-19 infection and its progression have a genetic predisposition. Majorly associated genetic variants are found in human leukocyte antigen (HLA), angiotensin convertase enzyme (ACE; rs1799752: ACE2; rs73635825), and transmembrane protease serine 2 (TMPRSS-2; rs12329760) genes. Identifying highly prone population having these variants is imperative for determining COVID-19 therapeutic strategies. Ayurveda (Indian traditional system of medicine) concept of Prakriti holds potential to predict genomic and phenotypic variations. Reported work on Prakriti correlates HLA-DR alleles with three broad phenotypes (Tridosha) described in Ayurveda (AyuGenomics). This is suggestive of differences in immune responses in individuals with specific constitutions. Therefore, the reported studies provide clues for clinically relevant hypotheses to be tested in systematic studies. The proposed approach of Ayurveda-based phenotype screening may offer a way ahead to design customized strategies for management of COVID-19 based on differences in Prakriti, immune response, and drug response. However, this needs clinical evaluation of the relation between Prakriti and genetic or phenotypic variants in COVID-19 prone and resistant populations.
    Keywords AyuGenomics ; Ayurveda ; Genomics ; Personalized medicine ; Integrative medicine ; SARS-CoV-2 ; Miscellaneous systems and treatments ; RZ409.7-999
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  3. Article: Exploring AyuGenomics approach for understanding COVID-19 predisposition and progression

    Bhat, Vedika / Borse, Swapnil / Chavan-Gautam, Preeti / Joshi, Kalpana

    Journal of Ayurveda and integrative medicine. 2022 Jan., Mar., v. 13, no. 1

    2022  

    Abstract: Recent reports on COVID-19 suggest that, the susceptibility to COVID-19 infection and ... strategies for management of COVID-19 based on differences in Prakriti, immune response, and drug response ... 19 prone and resistant populations. ...

    Abstract Recent reports on COVID-19 suggest that, the susceptibility to COVID-19 infection and its progression have a genetic predisposition. Majorly associated genetic variants are found in human leukocyte antigen (HLA), angiotensin convertase enzyme (ACE; rs1799752: ACE2; rs73635825), and transmembrane protease serine 2 (TMPRSS-2; rs12329760) genes. Identifying highly prone population having these variants is imperative for determining COVID-19 therapeutic strategies. Ayurveda (Indian traditional system of medicine) concept of Prakriti holds potential to predict genomic and phenotypic variations. Reported work on Prakriti correlates HLA-DR alleles with three broad phenotypes (Tridosha) described in Ayurveda (AyuGenomics). This is suggestive of differences in immune responses in individuals with specific constitutions. Therefore, the reported studies provide clues for clinically relevant hypotheses to be tested in systematic studies. The proposed approach of Ayurveda-based phenotype screening may offer a way ahead to design customized strategies for management of COVID-19 based on differences in Prakriti, immune response, and drug response. However, this needs clinical evaluation of the relation between Prakriti and genetic or phenotypic variants in COVID-19 prone and resistant populations.
    Keywords Ayurvedic medicine ; COVID-19 infection ; HLA antigens ; clinical examination ; drugs ; genetic predisposition to disease ; genomics ; immune response ; phenotype ; proteinases ; serine ; therapeutics
    Language English
    Dates of publication 2022-01
    Publishing place Elsevier B.V.
    Document type Article
    ISSN 0975-9476
    DOI 10.1016/j.jaim.2021.06.003
    Database NAL-Catalogue (AGRICOLA)

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    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

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