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  1. Book ; Audio / Video: Trachoma

    Wellcome Trust (London, England)

    (Topics in international health)

    2005  

    Abstract: ... prevention and treatment of trachoma through interactive tutorials: overview, aetiology and pathology ... Producer) This fully revised and updated CD-ROM provides an introduction to the diagnosis, control ... epidemiology and transmission, antibiotics, health promotion, environmental improvement, evaluation of the SAFE ...

    Author's details Wellcome Trust
    Series title Topics in international health
    Abstract (Producer) This fully revised and updated CD-ROM provides an introduction to the diagnosis, control, prevention and treatment of trachoma through interactive tutorials: overview, aetiology and pathology, epidemiology and transmission, antibiotics, health promotion, environmental improvement, evaluation of the SAFE strategy, clinical signs and grading, community assessment, and surgery.
    MeSH term(s) Trachoma
    Language English
    Size 1 CD-ROM :, col. ;, 4 3/4 in.
    Edition 2nd ed., Windows version.
    Publisher Trustee of the Wellcome Trust ; CABI Pub. distributor
    Publishing place London ; Wallingford, Oxfordshire ; Cambridge, MA
    Document type Book ; Audio / Video
    Note Title from disc label.
    ISBN 9780851999807 ; 0851999808
    Database Catalogue of the US National Library of Medicine (NLM)

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  2. Article ; Online: Trachoma: an update on prevention, diagnosis, and treatment.

    Bhosai, Satasuk Joy / Bailey, Robin L / Gaynor, Bruce D / Lietman, Thomas M

    Current opinion in ophthalmology

    2012  Volume 23, Issue 4, Page(s) 288–295

    Abstract: ... diagnosis, and treatment of trachoma.: Recent findings: Newer studies propose novel diagnostic tests ... Purpose of review: To review recent clinical and epidemiological studies regarding the prevention ... distributions remain a mainstay of treatment; studies have assessed the appropriate frequency and duration ...

    Abstract Purpose of review: To review recent clinical and epidemiological studies regarding the prevention, diagnosis, and treatment of trachoma.
    Recent findings: Newer studies propose novel diagnostic tests that appear sensitive for the detection of ocular chlamydial infection. For example, recent studies with ribosomal RNA-based nucleic acid amplification tests (NAATs) have demonstrated improved sensitivities compared to DNA-based NAATs; and the progression of scarring has now been characterized with confocal microscopy. Immunologic studies have further explored the etiology of clinical sequelae, suggesting that chronic inflammation can lead to progressive scarring even in the absence of Chlamydia. Mass oral azithromycin distributions remain a mainstay of treatment; studies have assessed the appropriate frequency and duration of treatment programs. Current studies have also explored ancillary effects of azithromycin distribution on mortality and bacterial infections.
    Summary: Trachoma programs have had remarkable success at reducing chlamydial infection and clinical signs of trachoma. Recent work suggests improved methods to monitor infection and scarring, and better ways to distribute treatment. Whereas studies continue to demonstrate reduction in infection in hyperendemic areas, more work is necessary to achieve elimination of this blinding disease.
    MeSH term(s) Anti-Bacterial Agents/administration & dosage ; Anti-Bacterial Agents/therapeutic use ; Azithromycin/therapeutic use ; Chlamydia Infections/diagnosis ; Chlamydia Infections/drug therapy ; Chlamydia Infections/prevention & control ; Chlamydia trachomatis/genetics ; Humans ; Nucleic Acid Amplification Techniques ; RNA, Ribosomal/genetics ; Trachoma/diagnosis ; Trachoma/drug therapy ; Trachoma/prevention & control
    Chemical Substances Anti-Bacterial Agents ; RNA, Ribosomal ; Azithromycin (83905-01-5)
    Language English
    Publishing date 2012-05-09
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1049383-9
    ISSN 1531-7021 ; 1040-8738
    ISSN (online) 1531-7021
    ISSN 1040-8738
    DOI 10.1097/ICU.0b013e32835438fc
    Database MEDical Literature Analysis and Retrieval System OnLINE

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