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  1. Article ; Online: Brainstem clinical and neurophysiological involvement in COVID-19.

    Bocci, Tommaso / Bulfamante, Gaetano / Campiglio, Laura / Coppola, Silvia / Falleni, Monica / Chiumello, Davide / Priori, Alberto

    Journal of neurology

    2021  Volume 268, Issue 10, Page(s) 3598–3600

    MeSH term(s) Brain Stem/diagnostic imaging ; COVID-19 ; Humans ; Neurophysiology ; SARS-CoV-2
    Language English
    Publishing date 2021-03-18
    Publishing country Germany
    Document type Letter
    ZDB-ID 187050-6
    ISSN 1432-1459 ; 0340-5354 ; 0012-1037 ; 0939-1517 ; 1619-800X
    ISSN (online) 1432-1459
    ISSN 0340-5354 ; 0012-1037 ; 0939-1517 ; 1619-800X
    DOI 10.1007/s00415-021-10474-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ui II Zs.40: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Brainstem involvement and respiratory failure in COVID-19.

    Manganelli, Fiore / Vargas, Maria / Iovino, Aniello / Iacovazzo, Carmine / Santoro, Lucio / Servillo, Giuseppe

    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology

    2020  Volume 41, Issue 7, Page(s) 1663–1665

    Abstract: ... that brainstem involvement may play a role in respiratory failure and perhaps in the high death rate of COVID-19 ... with an involvement of the brainstem and especially of respiratory centre thus possibly explaining the weaning failure ... suggested that brainstem might play a role in severe respiratory failure of COVID-19 patients. We described ...

    Abstract Respiratory failure is the most worrisome problem of COVID-19. Patients may develop severe pneumonia requiring invasive mechanical ventilation and a significant proportion of them dies. It has been suggested that brainstem might play a role in severe respiratory failure of COVID-19 patients. We described three COVID-19 patients in ICU at Federico II Hospital in Naples that, although had recovered from pneumonia, could not be weaned from invasive mechanical ventilation. Our clinical evaluation was consistent with an involvement of the brainstem and especially of respiratory centre thus possibly explaining the weaning failure in patients that were awake and had recovered from lung involvement. Our data, though limited, indicate that brainstem involvement may play a role in respiratory failure and perhaps in the high death rate of COVID-19 patients. Moreover, the weaning failure from mechanical ventilation due to central respiratory drive depression might underlie the unusual long stay in ICU reported for COVID-19 patients.
    MeSH term(s) Betacoronavirus ; Brain Stem/virology ; COVID-19 ; Coronavirus Infections/etiology ; Coronavirus Infections/mortality ; Coronavirus Infections/virology ; Humans ; Pandemics ; Pneumonia, Viral/etiology ; Pneumonia, Viral/mortality ; Pneumonia, Viral/virology ; Respiration, Artificial ; Respiratory Insufficiency/virology ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-05-29
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2016546-8
    ISSN 1590-3478 ; 1590-1874
    ISSN (online) 1590-3478
    ISSN 1590-1874
    DOI 10.1007/s10072-020-04487-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1877: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: Delayed onset Bickerstaff brainstem encephalitis overlapping Miller-Fisher Syndrome during SARS-CoV-2 infection.

    Acampora, R / de Falco, A / Lanfranchi, F / Montella, S / Scala, R / Lieto, M / Durante, L / Bruno, R

    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology

    2023  Volume 44, Issue 12, Page(s) 4179–4182

    Abstract: ... are included in the clinical spectrum of the "Fisher-Bickerstaff syndrome" ( Shahrizaila and Yuki in J ... Bickerstaff brainstem encephalitis (BBE) is a neuroimmunologic disease characterized by the acute ... onset of external ophthalmoplegia, ataxia, and consciousness disturbance, mostly subsequent ...

    Abstract Bickerstaff brainstem encephalitis (BBE) is a neuroimmunologic disease characterized by the acute onset of external ophthalmoplegia, ataxia, and consciousness disturbance, mostly subsequent to an infection. BBE is considered to be a variant of Miller-Fisher syndrome (MFS), which also exhibits external ophthalmoplegia and ataxia but not presenting consciousness alterations. Therefore, these two medical conditions are included in the clinical spectrum of the "Fisher-Bickerstaff syndrome" ( Shahrizaila and Yuki in J Neurol Neurosurg Psychiatry 84(5):576-583) [1]. With regard to the etiopathogenesis, increasing evidence worldwide suggests that SARS-CoV-2 infection-enhanced immune response is involved in a wide range of neurological complications such as Guillain-Barré syndrome (GBS), MFS, acute necrotizing encephalitis (ANE), myelitis, acute disseminated encephalomyelitis (ADEM), and, although very rarely, BBE either (Hosseini et al. in Rev Neurosci 32:671-691) [2]. We report a case of a patient affected by delayed onset BBE overlapping MFS during a mild SARS-CoV-2 infection. To the best of our knowledge, similar cases have never been reported.
    MeSH term(s) Humans ; Miller Fisher Syndrome/complications ; Miller Fisher Syndrome/diagnosis ; COVID-19/complications ; COVID-19/pathology ; SARS-CoV-2 ; Guillain-Barre Syndrome/complications ; Guillain-Barre Syndrome/diagnosis ; Encephalitis/complications ; Encephalitis/diagnosis ; Ophthalmoplegia ; Ataxia/complications ; Eye Diseases/complications ; Brain Stem/diagnostic imaging ; Brain Stem/pathology
    Language English
    Publishing date 2023-10-27
    Publishing country Italy
    Document type Case Reports ; Journal Article
    ZDB-ID 2016546-8
    ISSN 1590-3478 ; 1590-1874
    ISSN (online) 1590-3478
    ISSN 1590-1874
    DOI 10.1007/s10072-023-07142-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1877: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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