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Article: Severe Acute Respiratory Syndrome Coronavirus 2: The Emergence of Important Genetic Variants and Testing Options for Clinical Laboratories.

Buchan, Blake W / Yao, Joseph D

Clinical microbiology newsletter

2021  Volume 43, Issue 11, Page(s) 89–96

Abstract: Monitoring the spread of emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 ... variants of concern and their potential impacts and briefly describes testing strategies. ... variants relies on rapid genetic testing of the viral genome. The sequencing method commonly called next ...

Abstract Monitoring the spread of emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants relies on rapid genetic testing of the viral genome. The sequencing method commonly called next-generation sequencing can identify virus variants. At times, for target-specific mutation detection, reverse transcriptase polymerase chain reaction is used to identify specific variants. The Centers for Disease Control and Prevention's national SARS-CoV-2 Strain Surveillance Program is a comprehensive, population-based U.S. surveillance system to monitor SARS-CoV-2 genes, identifying emerging SARS-CoV-2 variants to determine implications for coronavirus disease 2019 (COVID-19) diagnostics, therapy, and vaccines. This review describes the main viral variants of concern and their potential impacts and briefly describes testing strategies.
Language English
Publishing date 2021-05-21
Publishing country United States
Document type Journal Article
ZDB-ID 985782-5
ISSN 1873-4391 ; 0196-4399
ISSN (online) 1873-4391
ISSN 0196-4399
DOI 10.1016/j.clinmicnews.2021.05.004
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