Article ; Online: Acral Changes in pediatric patients during COVID 19 pandemic: Registry report from the COVID 19 response task force of the society of pediatric dermatology (SPD) and pediatric dermatology research alliance (PeDRA).
2021 Volume 38, Issue 2, Page(s) 364–370
Abstract: ... COVID-19 Response Task Force of the Society for Pediatric Dermatology (SPD) and Pediatric Dermatology ... for demographics, description of acral lesions, symptoms before and after acral changes, COVID-19 positive contacts ... Research Alliance (PeDRA) and was managed by Children's Hospital of Philadelphia using REDCap.: Results ...
| Abstract | Background/objective: In spring 2020, high numbers of children presented with acral pernio-like skin rashes, concurrent with the coronavirus disease 2019 (COVID-19) pandemic. Understanding their clinical characteristics/ infection status may provide prognostic information and facilitate decisions about management. Methods: A pediatric-specific dermatology registry was created by the Pediatric Dermatology COVID-19 Response Task Force of the Society for Pediatric Dermatology (SPD) and Pediatric Dermatology Research Alliance (PeDRA) and was managed by Children's Hospital of Philadelphia using REDCap. Results: Data from 378 children 0-18 years entered into the registry between April 13 and July 17, 2020 were analyzed. Data were drawn from a standardized questionnaire completed by clinicians which asked for demographics, description of acral lesions, symptoms before and after acral changes, COVID-19 positive contacts, treatment, duration of skin changes, laboratory testing including SARS-CoV-2 PCR and antibody testing, as well as histopathology. 229 (60.6%) were male with mean age of 13.0 years (± 3.6 years). Six (1.6%) tested positive for SARS-CoV-2. Pedal lesions (often with pruritus and/or pain) were present in 96%. 30% (114/378) had COVID-19 symptoms during the 30 days prior to presentation. Most (69%) had no other symptoms and an uneventful course with complete recovery. Conclusions and relevance: Children with acral pernio-like changes were healthy and all recovered with no short-term sequelae. We believe these acral changes are not just a temporal epiphenomenon of shelter in place during the spring months of the first wave of the COVID-19 pandemic and may be a late phase reaction that needs further study. |
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| MeSH term(s) | Adolescent ; COVID-19 ; Child ; Dermatology/trends ; Humans ; Male ; Pandemics ; Pediatrics/trends ; Philadelphia ; Registries ; Skin Diseases/epidemiology | |||||
| Language | English | |||||
| Publishing date | 2021-03-20 | |||||
| Publishing country | United States | |||||
| Document type | Journal Article | |||||
| ZDB-ID | 605539-4 | |||||
| ISSN | 1525-1470 ; 0736-8046 | |||||
| ISSN (online) | 1525-1470 | |||||
| ISSN | 0736-8046 | |||||
| DOI | 10.1111/pde.14566 | |||||
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| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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