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Article ; Online: Evaluation of cochlear functions in infants exposed to SARS-CoV-2 intrauterine.

Celik, Turgut / Simsek, Agit / Koca, Cigdem Firat / Aydin, Sukru / Yasar, Seyma

American journal of otolaryngology

2021  Volume 42, Issue 4, Page(s) 102982

Abstract: ... Our results suggest an insufficiency in medial olivocochlear efferent system in infants exposed to SARS-CoV-2 ... intrauterine. Cochlear functions should be examined in infants whose mothers had COVID-19. ... Purpose: The novel coronavirus (SARS-CoV-2) caused an acute respiratory illness named COVID-19 and ...

Abstract Purpose: The novel coronavirus (SARS-CoV-2) caused an acute respiratory illness named COVID-19 and the disease spread all over the World. Fever, cough, fatigue, gastrointestinal infection symptoms form the main clinical symptoms. Pregnants and newborns form a vulnerable population and urgent measures must be addressed. Studies about the effect of COVID-19 on pregnant women, developing fetuses, and infants are limited. Various viral diseases can cause congenital or acquired, unilateral or bilateral hearing loss.
Methods: 37 infants whose mother was pregnant between March 2020 and December 2020 and were born after the diagnosis of COVID- 19 during pregnancy and 36 healthy infants were included in the study. Transient evoked otoacoustic emission (TEOAE), distortion product otoacoustic emission (DPOAE) and contralateral suppression of OAE (CLS OAE) tests were performed on all infants.
Results: According to the TEOAE results of patients and controls in the silent a statistically significant difference was observed between the two groups at 3 kHz and 4 kHz (p < 0.05). Contralateral suppression of OAE test results of patients and controls a statistically significant difference was found in all frequencies (p< 0.05). Suppression was much more effective at all frequencies in the normal group than patient group. This difference was found to be more significant at higher frequencies (2,3 and 4 kHz) (p < 0.001).
Conclusions: Our results suggest an insufficiency in medial olivocochlear efferent system in infants exposed to SARS-CoV-2 intrauterine. Cochlear functions should be examined in infants whose mothers had COVID-19.
MeSH term(s) Adult ; COVID-19/complications ; COVID-19/physiopathology ; Case-Control Studies ; Cochlea/physiopathology ; Evoked Potentials, Auditory/physiology ; Female ; Humans ; Infant, Newborn ; Male ; Otoacoustic Emissions, Spontaneous/physiology ; Pregnancy ; Pregnancy Complications, Infectious/physiopathology ; Pregnancy Complications, Infectious/virology ; SARS-CoV-2 ; Young Adult
Language English
Publishing date 2021-02-18
Publishing country United States
Document type Journal Article
ZDB-ID 604541-8
ISSN 1532-818X ; 0196-0709
ISSN (online) 1532-818X
ISSN 0196-0709
DOI 10.1016/j.amjoto.2021.102982
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