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Article ; Online: Pneumomediastinum in a patient with severe Covid-19 pneumonia.

Chang, Chee Yik

Revista da Sociedade Brasileira de Medicina Tropical

2021 Volume 54, Page(s) e03962021

MeSH term(s)	COVID-19 ; Humans ; Mediastinal Emphysema/diagnostic imaging ; Mediastinal Emphysema/etiology ; SARS-CoV-2 ; Tomography, X-Ray Computed
Language	English
Publishing date	2021-07-23
Publishing country	Brazil
Document type	Journal Article
ZDB-ID	1038126-0
ISSN	1678-9849 ; 0037-8682
ISSN (online)	1678-9849
ISSN	0037-8682
DOI	10.1590/0037-8682-0396-2021
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Article ; Online: Pneumomediastinum in a patient with severe Covid-19 pneumonia

Chee Yik Chang

Revista da Sociedade Brasileira de Medicina Tropical, Vol

2021 Volume 54

Keywords	Arctic medicine. Tropical medicine ; RC955-962
Language	English
Publishing date	2021-07-01T00:00:00Z
Publisher	Sociedade Brasileira de Medicina Tropical (SBMT)
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Spontaneous pneumomediastinum as a complication of COVID-19.

Zygmunt, Wojciech Grzegorz / Mackiewicz, Barbara / Siwiec, Jan / Milanowski, Janusz

Annals of agricultural and environmental medicine : AAEM

2023 Volume 30, Issue 2, Page(s) 394–397

Abstract: ... which in February 2020 was named COVID-19. The disease may have features of interstitial pneumonia and severe ... that it may complicate the course of interstitial lung disease in the course of COVID-19. The report describes two cases ... In December 2019, an atypical form of severe pneumonia emerged in Wuhan in China's Hubei province ...

Abstract	In December 2019, an atypical form of severe pneumonia emerged in Wuhan in China's Hubei province, which in February 2020 was named COVID-19. The disease may have features of interstitial pneumonia and severe respiratory failure requiring intensive oxygen therapy. Spontaneous pneumomediastinum is a rare pathological condition with air in the mediastinum outside the trachea, oesophagus and bronchi. It is potentially life-threatening complication of both invasive and non-invasive mechanical ventilation. There have been reports that it may complicate the course of interstitial lung disease in the course of COVID-19. The report describes two cases of young patients who spontaneously developed this complication. Immediate diagnose is important in order to applicate adequate procedures.
MeSH term(s)	Humans ; COVID-19/complications ; Mediastinal Emphysema/diagnostic imaging ; Mediastinal Emphysema/etiology ; Rare Diseases
Language	English
Publishing date	2023-06-20
Publishing country	Poland
Document type	Case Reports
ZDB-ID	1215115-4
ISSN	1898-2263 ; 1232-1966
ISSN (online)	1898-2263
ISSN	1232-1966
DOI	10.26444/aaem/166324
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Article ; Online: Successful lung-protective ventilatory management during the VV-ECMO in a severe COVID-19 pneumonia patient with extensive pneumomediastinum and subcutaneous emphysema: a case report.

Kohara, Jumpei / Kai, Shinichi / Hashimoto, Kazuya / Takatani, Yudai / Tanabe, Naoya / Hamada, Satoshi / Cho, Kosai / Tanaka, Tomoharu / Ito, Isao / Ohtsuru, Shigeru

JA clinical reports

2022 Volume 8, Issue 1, Page(s) 12

Abstract: ... should be performed thoroughly during VV-ECMO in severe COVID-19 pneumonia with pneumomediastinum ... subcutaneous emphysema is not established. Herein, we report a case of severe COVID-19 pneumonia with extensive ... hospital and diagnosed with COVID-19 pneumonia. His pulmonary parameters worsened during invasive ...

Abstract	Background: Ventilatory management of respiratory failure with pneumomediastinum/subcutaneous emphysema is not established. Herein, we report a case of severe COVID-19 pneumonia with extensive pneumomediastinum/subcutaneous emphysema, rescued by thorough lung-protective ventilatory management after applying the VV-ECMO. Case presentation: A 68-year-old male with no medical history was admitted to a local hospital and diagnosed with COVID-19 pneumonia. His pulmonary parameters worsened during invasive ventilation due to the development of pneumomediastinum/subcutaneous emphysema, and then he was transferred to our hospital. On arrival, we immediately decided to apply VV-ECMO and switch to ultraprotective ventilation. After maintaining the initial ventilation with a neuromuscular blocking agent for 2 days, we gradually increased PEEP while limiting PIP to 25 cmH Conclusions: Lung-protective ventilatory management should be performed thoroughly during VV-ECMO in severe COVID-19 pneumonia with pneumomediastinum/subcutaneous emphysema.
Language	English
Publishing date	2022-02-21
Publishing country	Germany
Document type	Journal Article
ISSN	2363-9024
ISSN (online)	2363-9024
DOI	10.1186/s40981-022-00505-8
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Article ; Online: Pneumomediastinum complicating COVID-19

Sérgio Henrique Bastos Damous / Jones Pessoa dos Santos Junior / Álvaro Vicente Alvarez Pezzano / Mohamad Abdul Majid Chams / Nathaly Haritov / Ricardo Waksman / Helber Vidal Gadelha Lima / Jocielle dos Santos Miranda / Roberto Rasslan / Edivaldo Massazo Utiyama

European Journal of Medical Research, Vol 26, Iss 1, Pp 1-

a case series

2021 Volume 6

Abstract: ... Pneumomediastinum is a rare complication of COVID-19 pneumonia, and the most likely etiopathogenesis is severe ... Abstract Background Pneumomediastinum is a rare complication of COVID-19 pneumonia, which may or ... we present a series of four patients with severe pneumomediastinum requiring intensive care unit ...

Abstract	Abstract Background Pneumomediastinum is a rare complication of COVID-19 pneumonia, which may or may not be associated with invasive ventilatory support. Therefore, the report and findings associated with its evolution can be of great contribution in the management of this unknown disease. Case presentation Here, we present a series of four patients with severe pneumomediastinum requiring intensive care unit. These patients developed pneumomediastinum before or during orotracheal intubation (OTI) or without OTI. The four patients were three men and one woman with a mean age of 60.5 years (48–74 years). No patients had a known history of lung disease or traumatic events, except for one patient who had a history of smoking, but who was without parenchymal disease. All intubations were performed without complications. No cases of pneumomediastinum occurred after tracheostomy, and none of the patients had tomographic or bronchoscopic evidence of tracheal injury. Although the pneumomediastinum observed in our cases was apparently not related to a violation of the aerodigestive track, this complication was associated with a worse prognosis. Conclusion Pneumomediastinum is a rare complication of COVID-19 pneumonia, and the most likely etiopathogenesis is severe pulmonary involvement, which may or may not be associated with invasive ventilatory support. Future studies with a greater number of cases should elucidate the relationship of pneumomediastinum to a probable prognostic factor.
Keywords	COVID-19 ; SARS-CoV-2 ; Pneumomediastinum ; Medicine ; R
Subject code	610 ; 616
Language	English
Publishing date	2021-09-01T00:00:00Z
Publisher	BMC
Document type	Article ; Online
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Article ; Online: Spontaneous pneumomediastinum in patients with COVID-19 pneumonia.

Abid, Narjes / Nemsi, Ella / Loukil, Manel / Gader, Nada / Ben Ali, Mechaal / Ghrairi, Hedia

La Tunisie medicale

2023 Volume 101, Issue 2, Page(s) 313–316

Abstract: ... performed in front of any sudden deterioration in respiratory status of patients with COVID-19 pneumonia ... few cases have been reported during this ongoing global pandemic of Coronavirus-2019 (COVID-19 ... forms of COVID-19. ...

Abstract	Introduction: Spontaneous pneumomediastinum (SPM) is a rare affection in general population. Only few cases have been reported during this ongoing global pandemic of Coronavirus-2019 (COVID-19). The ethipathogeny of this complication is poorly understood. Observations: we reported ten cases of SPM complicating coronavirus pneumonia. There were six me and four women. Age varies from 32 to 66 years. Pneumonia was severe for all cases defined by a bloo oxygen saturation < 90% on admission. All patients were hospitalized in intensive care unit and treated by high-flow oxygen for nine patients and non-rebreather masks for one patient. Repeated chest computed tomography (CT) scan showed resolution of the pneumomediastinum and appearance of signs of pulmonary fibrosis for four cases. Conclusions: Chest CT scan must be performed in front of any sudden deterioration in respiratory status of patients with COVID-19 pneumonia to not miss mechanical complication such as SPM. This complication seems to be associated with severe forms of COVID-19.
MeSH term(s)	Humans ; Female ; Adult ; Middle Aged ; Aged ; Mediastinal Emphysema/diagnosis ; Mediastinal Emphysema/etiology ; COVID-19/complications ; Pneumonia ; Oxygen ; Hospitalization
Chemical Substances	Oxygen (S88TT14065)
Language	English
Publishing date	2023-02-12
Publishing country	Tunisia
Document type	Journal Article
ZDB-ID	128627-4
ISSN	2724-7031 ; 0041-4131
ISSN (online)	2724-7031
ISSN	0041-4131
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Article: COVID-19 Pneumonia Complicated by Pneumomediastinum: A Case Report.

Cardoso, João / Castro, Ivo / Gaspar, Vasco / Esteves, Cristina

Cureus

2022 Volume 14, Issue 12, Page(s) e32508

Abstract: ... with COVID-19 pneumonia and due to severe refractory hypoxemia, she was submitted to therapy ... of considering pneumomediastinum as a complication of COVID-19 pneumonia in cases subjected ... Coronavirus disease 2019 (COVID-19) is a pandemic that spread rapidly around the world, causing ...

Abstract	Coronavirus disease 2019 (COVID-19) is a pandemic that spread rapidly around the world, causing an enormous overload on the health systems of the different affected countries. Among the many different manifestations of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, an uncommon complication is the development of pneumomediastinum. In the clinical case presented, the patient was diagnosed with COVID-19 pneumonia and due to severe refractory hypoxemia, she was submitted to therapy with non-invasive ventilation (NIV). After initial stabilization and improvement, there was unexpected clinical deterioration and pneumomediastinum was diagnosed. The purpose of this report is to highlight the importance of considering pneumomediastinum as a complication of COVID-19 pneumonia in cases subjected to non-invasive ventilation.
Language	English
Publishing date	2022-12-14
Publishing country	United States
Document type	Case Reports
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.32508
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Spontaneous Pneumomediastinum in COVID-19 Pneumonia: A Rare Occurence.

Zafar, Saerah Iffat / Nasir, Hina / Halim, Aliya / Slehria, Atiq Ur Rehman / Zafar, Nadeem

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP

2022 Volume 32, Issue 2, Page(s) 230–232

Abstract: ... with spontaneous pneumomediastinum had moderate to severe degree of COVID pneumonia; mortality in patients ... Imaging (AFIRI), Rawalpindi, Pakistan. All COVID positive patients having spontaneous pneumomediastinum ... Spontaneous pneumomediastinum with COVID pneumonia is a rare occurrence with or ...

Abstract	Spontaneous pneumomediastinum with COVID pneumonia is a rare occurrence with or without accompanying subcutaneous emphysema or pneumothorax. The aim of this study was to establish relation of this complication to severity of lung disease and its clinical outcome. The study was conducted for a period of seven months from April to October 2020 in the CT Department of Armed Forces Institute of Radiology and Imaging (AFIRI), Rawalpindi, Pakistan. All COVID positive patients having spontaneous pneumomediastinum on high resolution CT (HRCT) chest were included (n=14). These patients were assessed for severity of lung disease as per CT severity score (CTSS), and were followed up for their clinical outcome. All patients with spontaneous pneumomediastinum had moderate to severe degree of COVID pneumonia; mortality in patients with pneumomediastinum was 50%; and was seen in those patients who had greater severity of lung disease as per the CTSS. Key Words: Spontaneous, Pneumomediastinum, COVID, Pneumothorax, Subcutaneous, Emphysema.
MeSH term(s)	COVID-19 ; Humans ; Mediastinal Emphysema/diagnostic imaging ; Mediastinal Emphysema/etiology ; Pneumothorax/diagnostic imaging ; Pneumothorax/etiology ; SARS-CoV-2 ; Subcutaneous Emphysema/diagnostic imaging ; Subcutaneous Emphysema/etiology
Language	English
Publishing date	2022-02-02
Publishing country	Pakistan
Document type	Journal Article
ZDB-ID	2276646-7
ISSN	1681-7168 ; 1022-386X
ISSN (online)	1681-7168
ISSN	1022-386X
DOI	10.29271/jcpsp.2022.02.230
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Article: COVID-19 and pneumothorax, pneumomediastinum, subcutaneous emphysema: Analysis of risk factors.

Büyükkarabacak, Yasemin / Pirzirenli, Mehmet Gökhan / Gurz, Selçuk / Abacı, Hasan / Taslak Şengül, Ayşen / Çelik, Burçin / Basoğlu, Ahmet

Turk gogus kalp damar cerrahisi dergisi

2023 Volume 31, Issue 1, Page(s) 69–77

Abstract: ... complication, particularly in mechanically ventilated patients who have COVID-19 pneumonia with severe acute ... followed in the intensive care unit due to novel coronavirus disease 2019 (COVID-19) pneumonia.: Methods ... years; range, 11 to 91 years) who were followed in the intensive care unit due to COVID-19 pneumonia and ...

Abstract	Background: In this study, we aimed to analyze the risk factors of barotrauma in patients who were followed in the intensive care unit due to novel coronavirus disease 2019 (COVID-19) pneumonia. Methods: Between March 2020 and January 2021, a total of 261 patients (155 males, 106 females; mean age: 63.3±15.3 years; range, 11 to 91 years) who were followed in the intensive care unit due to COVID-19 pneumonia and were diagnosed with pneumothorax, pneumomediastinum, and subcutaneous emphysema were retrospectively analyzed. Demographics data of the patients, past and current medical history, clinical management, patient progress, and survival data were obtained from medical records of our hospital. Results: Twenty-seven of the patients were diagnosed with barotrauma. A total of 88.8% of the patients were followed with intubation. The development of pneumothorax, pneumomediastinum, and subcutaneous emphysema due to barotrauma was not dependent on sex, smoking/non-smoking status, using/not using corticosteroids, or comorbid diseases. There was a significant correlation between pneumothorax, pneumomediastinum, and subcutaneous emphysema development in intubated patients with different ventilator modes. Changing the ventilator mode from synchronized intermittent mandatory ventilation to airway pressure release ventilation increased the possibility of barotrauma by 15 times. Conclusion: Despite all lung-protective applications, barotrauma is a common complication, particularly in mechanically ventilated patients who have COVID-19 pneumonia with severe acute respiratory distress syndrome. Mechanical ventilator pressure modes should be patientspecific and followed carefully and frequently for the risk of barotrauma.
Language	English
Publishing date	2023-01-30
Publishing country	Turkey
Document type	Journal Article
ISSN	1301-5680
ISSN	1301-5680
DOI	10.5606/tgkdc.dergisi.2023.23081
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Article ; Online: Pneumomediastinum as a predictor of negative prognosis in patients with coronavirus pneumonia

Yu. S. Kuznetsov / V. M. Durleshter / V. A. Pshukov / V. V. Markin / А. А. Kryachko / S. V. Shchyplyak / D. S. Murashko / V. A. Rudko

Сибирский научный медицинский журнал, Vol 43, Iss 2, Pp 103-

2023 Volume 108

Abstract: ... mediastinal emphysema in patients with COVID-19 signifcantly more often leads to the development of acute respiratory ... outcome. Conclusions. Pneumomediastinum in patients with viral pneumonia caused by a new ... Aim of the study was to analyze the course of coronavirus pneumonia in patients ...

Abstract	Aim of the study was to analyze the course of coronavirus pneumonia in patients with pneumomediastinum. Material and methods. The study included 139 patients, 71 of whom developed spontaneous pneumomediastinum against the background of coronavirus pneumonia. Laboratory, clinical and radiological data were analyzed and compared. Results. The relationship between the severity of viral pneumonia (3rd–4th degree of severity according to MSCT) and pneumomediastinum was revealed. It was found that spontaneous mediastinal emphysema in patients with COVID-19 signifcantly more often leads to the development of acute respiratory distress syndrome, multiple organ failure and can be a predictor of negative prognosis of the disease outcome. Conclusions. Pneumomediastinum in patients with viral pneumonia caused by a new coronavirus infection is a predictor of severe disease and poor prognosis. With an increase in spontaneous mediastinal emphysema without pneumothorax, it is recommended to perform mediastinotomy according to Razumovsky’s indications, and in case of clinically signifcant concomitant pneumothorax – drainage and revision of the mediastinum.
Keywords	covid-19 ; pneumonia ; pneumomediastinum ; unfavorable prognosis ; drainage ; comorbid conditions ; Medicine ; R
Subject code	610
Language	Russian
Publishing date	2023-04-01T00:00:00Z
Publisher	Russian Academy of Sciences, Siberian Branch Publishing House
Document type	Article ; Online
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