Article ; Online: Potential Interaction Between SARS-CoV-2 and Thyroid: A Review.
2021 Volume 162, Issue 3
Abstract: ... interaction between SARS-CoV-2 and the thyroid is poorly understood. In contrast to SARS-CoV-1, limited ... its metabolism. COVID-19 and thyroid disease may mutually aggravate the disease burden. Patients with SARS-CoV-2 ... available evidence indicates there is no pathological evidence of thyroid injury caused by SARS-CoV-2 ...
| Abstract | The novel coronavirus disease 2019 (COVID-19) produced by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is sweeping the world in a very short time. Although much has been learned about the clinical course, prognostic inflammatory markers, and disease complications of COVID-19, the potential interaction between SARS-CoV-2 and the thyroid is poorly understood. In contrast to SARS-CoV-1, limited available evidence indicates there is no pathological evidence of thyroid injury caused by SARS-CoV-2. However, subacute thyroiditis caused by SARS-CoV-2 has been reported for the first time. Thyroid dysfunction is common in patients with COVID-19 infection. By contrast, certain thyroid diseases may have a negative impact on the prevention and control of COVID-19. In addition, some anti-COVID-19 agents may cause thyroid injury or affect its metabolism. COVID-19 and thyroid disease may mutually aggravate the disease burden. Patients with SARS-CoV-2 infection should not ignore the effect on thyroid function, especially when there are obvious related symptoms. In addition, patients with thyroid diseases should follow specific management principles during the epidemic period. |
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| MeSH term(s) | Adrenal Cortex Hormones/therapeutic use ; COVID-19/complications ; COVID-19/epidemiology ; Comorbidity ; Female ; Heparin, Low-Molecular-Weight/therapeutic use ; Humans ; Male ; SARS-CoV-2 ; Thyroid Diseases/epidemiology ; Thyroid Diseases/physiopathology ; Thyroid Diseases/therapy ; Thyroid Gland/drug effects ; Thyroid Gland/physiopathology ; Thyroid Gland/virology ; Thyroiditis/virology ; Thyrotropin/blood ; Triiodothyronine/therapeutic use ; COVID-19 Drug Treatment | |||||
| Chemical Substances | Adrenal Cortex Hormones ; Heparin, Low-Molecular-Weight ; Triiodothyronine (06LU7C9H1V) ; Thyrotropin (9002-71-5) | |||||
| Language | English | |||||
| Publishing date | 2021-02-05 | |||||
| Publishing country | United States | |||||
| Document type | Journal Article ; Research Support, Non-U.S. Gov't ; Review | |||||
| ZDB-ID | 427856-2 | |||||
| ISSN | 1945-7170 ; 0013-7227 | |||||
| ISSN (online) | 1945-7170 | |||||
| ISSN | 0013-7227 | |||||
| DOI | 10.1210/endocr/bqab004 | |||||
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| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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