Article ; Online: Fatal Exacerbations of Systemic Capillary Leak Syndrome Complicating Coronavirus Disease.
2021 Volume 27, Issue 10, Page(s) 2529–2534
Abstract: We report 2 fatal exacerbations of systemic capillary leak syndrome (SCLS), also known ... to complications of SCLS induced by infection with severe acute respiratory syndrome coronavirus 2. Persons ... as Clarkson disease, associated with coronavirus disease (COVID-19) in the United States. One patient carried ...
| Abstract | We report 2 fatal exacerbations of systemic capillary leak syndrome (SCLS), also known as Clarkson disease, associated with coronavirus disease (COVID-19) in the United States. One patient carried an established diagnosis of SCLS and the other sought treatment for new-onset hypotensive shock, hemoconcentration, and anasarca, classic symptoms indicative of an SCLS flare. Both patients had only mild-to-moderate symptoms of COVID-19. This clinical picture suggests that these patients succumbed to complications of SCLS induced by infection with severe acute respiratory syndrome coronavirus 2. Persons with known or suspected SCLS may be at increased risk for developing a disease flare in the setting of mild-to-moderate COVID-19 infection. |
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| MeSH term(s) | COVID-19 ; Capillary Leak Syndrome/diagnosis ; Capillary Leak Syndrome/etiology ; Humans ; SARS-CoV-2 ; United States |
| Language | English |
| Publishing date | 2021-07-27 |
| Publishing country | United States |
| Document type | Journal Article ; Research Support, N.I.H., Intramural ; Review |
| ZDB-ID | 1380686-5 |
| ISSN | 1080-6059 ; 1080-6040 |
| ISSN (online) | 1080-6059 |
| ISSN | 1080-6040 |
| DOI | 10.3201/eid2710.211155 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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