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Article ; Online: Management of liver diseases during the pandemic of coronavirus disease-19.

Cho, Ju-Yeon / Kim, Soon Sun / Lee, Young-Sun / Song, Do Seon / Lee, Jeong-Hoon / Kim, Ji Hoon

2020 Volume 26, Issue 3, Page(s) 243–250

MeSH term(s)	Antiviral Agents/therapeutic use ; Betacoronavirus/isolation & purification ; COVID-19 ; Carcinoma, Hepatocellular/pathology ; Carcinoma, Hepatocellular/therapy ; Coronavirus Infections/complications ; Coronavirus Infections/drug therapy ; Coronavirus Infections/epidemiology ; Coronavirus Infections/pathology ; Cross Infection/prevention & control ; Drug Interactions ; Humans ; Immunosuppressive Agents/therapeutic use ; Liver Diseases/complications ; Liver Diseases/pathology ; Liver Diseases/prevention & control ; Liver Neoplasms/pathology ; Liver Neoplasms/therapy ; Liver Transplantation ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/drug therapy ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/pathology ; SARS-CoV-2
Chemical Substances	Antiviral Agents ; Immunosuppressive Agents
Keywords	covid19
Language	English
Publishing date	2020-06-23
Publishing country	Korea (South)
Document type	Journal Article ; Practice Guideline
ZDB-ID	2672560-5
ISSN	2287-285X ; 2287-2728
ISSN (online)	2287-285X
ISSN	2287-2728
DOI	10.3350/cmh.2020.0111
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Article ; Online: Update on liver disease management during the pandemic of coronavirus disease 2019 (COVID-19): 2021 KASL guideline.

Cho, Ju-Yeon / Lee, Young-Sun / Kim, Soon Sun / Song, Do Seon / Lee, Jeong-Hoon / Kim, Ji Hoon

Clinical and molecular hepatology

2021 Volume 27, Issue 4, Page(s) 515–523

MeSH term(s)	COVID-19 ; Disease Management ; Humans ; Liver Neoplasms/epidemiology ; Pandemics ; SARS-CoV-2
Language	English
Publishing date	2021-09-17
Publishing country	Korea (South)
Document type	Journal Article
ZDB-ID	2672560-5
ISSN	2287-285X ; 2287-2728
ISSN (online)	2287-285X
ISSN	2287-2728
DOI	10.3350/cmh.2021.0293
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Article: Management of liver diseases during the pandemic of coronavirus disease-19

Cho, Ju-Yeon / Kim, Soon Sun / Lee, Young-Sun / Song, Do Seon / Lee, Jeong-Hoon / Kim, Ji Hoon

Clin Mol Hepatol

Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #612052
Database	COVID19

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Article ; Online: Management of liver diseases during the pandemic of coronavirus disease-19

Ju-Yeon Cho / Soon Sun Kim / Young-Sun Lee / Do Seon Song / Jeong-Hoon Lee / Ji Hoon Kim

Clinical and Molecular Hepatology, Vol 26, Iss 3, Pp 243-

2020 Volume 250

Keywords	sars-cov-2 ; covid-19 ; hepatocelluar carcinoma ; liver cirrhosis ; hepatitis ; Diseases of the digestive system. Gastroenterology ; RC799-869 ; covid19
Language	English
Publishing date	2020-07-01T00:00:00Z
Publisher	Korean Association for the Study of the Liver
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Worldwide management of hepatocellular carcinoma during the COVID-19 pandemic.

Inchingolo, Riccardo / Acquafredda, Fabrizio / Tedeschi, Michele / Laera, Letizia / Surico, Gianmarco / Surgo, Alessia / Fiorentino, Alba / Spiliopoulos, Stavros / de'Angelis, Nicola / Memeo, Riccardo

World journal of gastroenterology

2021 Volume 27, Issue 25, Page(s) 3780–3789

Abstract: ... worldwide regarding the management of hepatocellular carcinoma during the COVID-19 pandemic were reviewed. ... The coronavirus disease 2019 (COVID-19) pandemic has impacted hospital organization ... types of liver cancer, has also required a different management during this period in order to optimize ...

Abstract	The coronavirus disease 2019 (COVID-19) pandemic has impacted hospital organization, with the necessity to quickly react to face the pandemic. The management of the oncological patient has been modified by necessity due to different allocation of nurses and doctors, requiring new strategies to guarantee the correct assistance to the patients. Hepatocellular carcinoma, considered as one of the most aggressive types of liver cancer, has also required a different management during this period in order to optimize the management of patients at risk for and with this cancer. The aim of this document is to review recommendations on hepatocellular carcinoma surveillance and management, including surgery, liver transplantation, interventional radiology, oncology, and radiotherapy. Publications and guidelines from the main scientific societies worldwide regarding the management of hepatocellular carcinoma during the COVID-19 pandemic were reviewed.
MeSH term(s)	COVID-19 ; Carcinoma, Hepatocellular/epidemiology ; Carcinoma, Hepatocellular/therapy ; Humans ; Liver Neoplasms/epidemiology ; Liver Neoplasms/therapy ; Pandemics ; SARS-CoV-2
Language	English
Publishing date	2021-07-28
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	2185929-2
ISSN	2219-2840 ; 1007-9327
ISSN (online)	2219-2840
ISSN	1007-9327
DOI	10.3748/wjg.v27.i25.3780
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Article ; Online: Assessing the impact of COVID-19 on liver cancer management (CERO-19).

Muñoz-Martínez, Sergio / Sapena, Victor / Forner, Alejandro / Nault, Jean-Charles / Sapisochin, Gonzalo / Rimassa, Lorenza / Sangro, Bruno / Bruix, Jordi / Sanduzzi-Zamparelli, Marco / Hołówko, Wacław / El Kassas, Mohamed / Mocan, Tudor / Bouattour, Mohamed / Merle, Philippe / Hoogwater, Frederik J H / Alqahtani, Saleh A / Reeves, Helen L / Pinato, David J / Giorgakis, Emmanouil /

Meyer, Tim / Villadsen, Gerda Elisabeth / Wege, Henning / Salati, Massimiliano / Mínguez, Beatriz / Di Costanzo, Giovan Giuseppe / Roderburg, Christoph / Tacke, Frank / Varela, María / Galle, Peter R / Alvares-da-Silva, Mario Reis / Trojan, Jörg / Bridgewater, John / Cabibbo, Giuseppe / Toso, Christian / Lachenmayer, Anja / Casadei-Gardini, Andrea / Toyoda, Hidenori / Lüdde, Tom / Villani, Rosanna / Matilla Peña, Ana María / Guedes Leal, Cassia Regina / Ronzoni, Monica / Delgado, Manuel / Perelló, Christie / Pascual, Sonia / Lledó, José Luis / Argemi, Josepmaria / Basu, Bristi / da Fonseca, Leonardo / Acevedo, Juan / Siebenhüner, Alexander R / Braconi, Chiara / Meyers, Brandon M / Granito, Alessandro / Sala, Margarita / Rodríguez-Lope, Carlos / Blaise, Lorraine / Romero-Gómez, Manuel / Piñero, Federico / Gomez, Dhanny / Mello, Vivianne / Pinheiro Alves, Rogerio Camargo / França, Alex / Branco, Fernanda / Brandi, Giovanni / Pereira, Gustavo / Coll, Susanna / Guarino, Maria / Benítez, Carlos / Anders, Maria Margarita / Bandi, Juan C / Vergara, Mercedes / Calvo, Mariona / Peck-Radosavljevic, Markus / García-Juárez, Ignacio / Cardinale, Vincenzo / Lozano, Mar / Gambato, Martina / Okolicsanyi, Stefano / Morales-Arraez, Dalia / Elvevi, Alessandra / Muñoz, Alberto E / Lué, Alberto / Iavarone, Massimo / Reig, Maria

JHEP reports : innovation in hepatology

2021 Volume 3, Issue 3, Page(s) 100260

Abstract: Background & aims: The coronavirus disease 2019 (COVID-19) pandemic has posed unprecedented ... decision-making.: Lay summary: The coronavirus disease 2019 (COVID-19) pandemic has posed unprecedented ... intrahepatic cholangiocarcinoma, cared for around the world during the first COVID-19 pandemic wave.: Results ...

Abstract	Background & aims: The coronavirus disease 2019 (COVID-19) pandemic has posed unprecedented challenges to healthcare systems and it may have heavily impacted patients with liver cancer (LC). Herein, we evaluated whether the schedule of LC screening or procedures has been interrupted or delayed because of the COVID-19 pandemic. Methods: An international survey evaluated the impact of the COVID-19 pandemic on clinical practice and clinical trials from March 2020 to June 2020, as the first phase of a multicentre, international, and observational project. The focus was on patients with hepatocellular carcinoma or intrahepatic cholangiocarcinoma, cared for around the world during the first COVID-19 pandemic wave. Results: Ninety-one centres expressed interest to participate and 76 were included in the analysis, from Europe, South America, North America, Asia, and Africa (73.7%, 17.1%, 5.3%, 2.6%, and 1.3% per continent, respectively). Eighty-seven percent of the centres modified their clinical practice: 40.8% the diagnostic procedures, 80.9% the screening programme, 50% cancelled curative and/or palliative treatments for LC, and 41.7% modified the liver transplantation programme. Forty-five out of 69 (65.2%) centres in which clinical trials were running modified their treatments in that setting, but 58.1% were able to recruit new patients. The phone call service was modified in 51.4% of centres which had this service before the COVID-19 pandemic (n = 19/37). Conclusions: The first wave of the COVID-19 pandemic had a tremendous impact on the routine care of patients with liver cancer. Modifications in screening, diagnostic, and treatment algorithms may have significantly impaired the outcome of patients. Ongoing data collection and future analyses will report the benefits and disadvantages of the strategies implemented, aiding future decision-making. Lay summary: The coronavirus disease 2019 (COVID-19) pandemic has posed unprecedented challenges to healthcare systems globally. Herein, we assessed the impact of the first wave pandemic on patients with liver cancer and found that routine care for these patients has been majorly disrupted, which could have a significant impact on outcomes.
Language	English
Publishing date	2021-02-23
Publishing country	Netherlands
Document type	Journal Article
ISSN	2589-5559
ISSN (online)	2589-5559
DOI	10.1016/j.jhepr.2021.100260
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Article: [Liver disease during the pandemic of COVID-19 infection: prediction of the course and tactics of management: A review].

Maev, I V / Osadchuk, M A

Terapevticheskii arkhiv

2022 Volume 94, Issue 11, Page(s) 1326–1332

Abstract: ... of CoronaVIrus Disease 2019 (COVID-19). This aspect is most clinically relevant in patients with pre-existing ... chronic liver disease (CKD), who are at extremely high risk of severe COVID-19 and death. Risk factors ... for severe CKD, especially in people with liver cirrhosis and non-alcoholic fatty liver disease, are ...

Abstract	The hepatic consequences of SARS-CoV-2 infection are now recognized as an important component of CoronaVIrus Disease 2019 (COVID-19). This aspect is most clinically relevant in patients with pre-existing chronic liver disease (CKD), who are at extremely high risk of severe COVID-19 and death. Risk factors for severe CKD, especially in people with liver cirrhosis and non-alcoholic fatty liver disease, are the direct and indirect cytotoxic effects of coronavirus against the background of systemic inflammation, blood clotting disorders and immune dysfunction. The severe negative impact of the pandemic in the presence of CKD and the difficulties of patient relationships contribute to the progressive increase in the global burden of liver disease on the health system.
MeSH term(s)	Humans ; COVID-19 ; Pandemics ; SARS-CoV-2 ; Non-alcoholic Fatty Liver Disease/diagnosis ; Non-alcoholic Fatty Liver Disease/epidemiology ; Non-alcoholic Fatty Liver Disease/therapy ; Renal Insufficiency, Chronic
Language	Russian
Publishing date	2022-12-26
Publishing country	Russia (Federation)
Document type	Review ; English Abstract ; Journal Article
ZDB-ID	40718-5
ISSN	2309-5342 ; 0040-3660
ISSN (online)	2309-5342
ISSN	0040-3660
DOI	10.26442/00403660.2022.11.201934
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Article ; Online: Management of Liver Tumors during the COVID-19 Pandemic

Irene Bargellini / Giuseppe Boni / Antonio Claudio Traino / Elena Bozzi / Giulia Lorenzoni / Francesca Bianchi / Rosa Cervelli / Tommaso Depalo / Laura Crocetti / Duccio Volterrani / Roberto Cioni

Journal of Clinical Medicine, Vol 10, Iss 4315, p

The Added Value of Selective Internal Radiation Therapy (SIRT)

2021 Volume 4315

Abstract: Background: In the context of the coronavirus disease 2019 (COVID-19) pandemic, liver-directed ... of this study is to present our experience with SIRT during the first wave of COVID-19 pandemic and provide ... 56.7% and 72.2%, respectively. Conclusion: The first wave of the COVID-19 pandemic was characterized ...

Abstract	Background: In the context of the coronavirus disease 2019 (COVID-19) pandemic, liver-directed therapies (LDTs) may offer minimally invasive integrative tools for tumor control. Among them, selective internal radiation therapy (SIRT) represents a safe, flexible and effective treatment. Purpose of this study is to present our experience with SIRT during the first wave of COVID-19 pandemic and provide an overview of the indications and challenges of SIRT in this scenario. Methods: We retrospectively analyzed the number of patients evaluated by Multidisciplinary Liver Tumor Board (MLTB) and who were undergoing LDTs between March and July 2020 and compared it with 2019. For patients treated with SIRT, clinical data, treatment details and the best radiological response were collected. Results: Compared to 2019, we observed a 27.5% reduction in the number of patients referred to MLTB and a 28.3% decrease in percutaneous ablations; transarterial chemoembolizations were stable, while SIRT increased by 64%. The majority of SIRT patients (75%) had primary tumors, mostly HCC. The best objective response and disease control rates were 56.7% and 72.2%, respectively. Conclusion: The first wave of the COVID-19 pandemic was characterized by an increased demand for SIRT, which represents a safe, flexible and effective treatment, whose manageability will further improve by simplifying the treatment workflow, developing user-friendly and reliable tools for personalized dosimetry and improving interdisciplinary communication.
Keywords	radioembolization ; yttrium ; holmium ; hepatocellular carcinoma ; cholangiocarcinoma ; liver cancer ; Medicine ; R
Subject code	610
Language	English
Publishing date	2021-09-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Unchanged surgical management of patients with Cholangiocarcinoma during the COVID-19 pandemic.

Gringeri, Enrico / Gambato, Martina / Furlanetto, Alessandro / Ballo, Mattia / Nieddu, Eleonora / Cillo, Umberto

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver

2020 Volume 52, Issue 9, Page(s) 944–945

MeSH term(s)	Betacoronavirus ; Bile Duct Neoplasms ; Bile Ducts, Intrahepatic ; COVID-19 ; Cholangiocarcinoma ; Coronavirus Infections ; Humans ; Klatskin Tumor ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2
Keywords	covid19
Language	English
Publishing date	2020-07-06
Publishing country	Netherlands
Document type	Letter ; Comment
ZDB-ID	1459373-7
ISSN	1878-3562 ; 1125-8055
ISSN (online)	1878-3562
ISSN	1125-8055
DOI	10.1016/j.dld.2020.06.033
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Article ; Online: Management of patients with autoimmune liver disease during COVID-19 pandemic.

Lleo, Ana / Invernizzi, Pietro / Lohse, Ansgar W / Aghemo, Alessio / Carbone, Marco

Journal of hepatology

2020 Volume 73, Issue 2, Page(s) 453–455

MeSH term(s)	Betacoronavirus ; COVID-19 ; Coronavirus Infections/prevention & control ; Coronavirus Infections/virology ; Hepatitis, Autoimmune/drug therapy ; Humans ; Immunocompromised Host ; Immunosuppressive Agents/therapeutic use ; Infection Control/methods ; Liver Cirrhosis/drug therapy ; Pandemics/prevention & control ; Pneumonia, Viral/prevention & control ; Pneumonia, Viral/virology ; SARS-CoV-2 ; Telemedicine/methods
Chemical Substances	Immunosuppressive Agents
Keywords	covid19
Language	English
Publishing date	2020-04-10
Publishing country	Netherlands
Document type	Letter
ZDB-ID	605953-3
ISSN	1600-0641 ; 0168-8278
ISSN (online)	1600-0641
ISSN	0168-8278
DOI	10.1016/j.jhep.2020.04.002
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