Article ; Online: Introduction of ORF3a-Q57H SARS-CoV-2 Variant Causing Fourth Epidemic Wave of COVID-19, Hong Kong, China.
2021 Volume 27, Issue 5, Page(s) 1492–1495
Abstract: ... a fourth wave of coronavirus disease in Hong Kong. The virus has an ORF3a-Q57H mutation, causing truncation ... We describe an introduction of clade GH severe acute respiratory syndrome coronavirus 2 causing ...
Abstract | We describe an introduction of clade GH severe acute respiratory syndrome coronavirus 2 causing a fourth wave of coronavirus disease in Hong Kong. The virus has an ORF3a-Q57H mutation, causing truncation of ORF3b. This virus evades induction of cytokine, chemokine, and interferon-stimulated gene expression in primary human respiratory cells. |
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MeSH term(s) | COVID-19 ; China ; Epidemics ; Hong Kong/epidemiology ; Humans ; SARS-CoV-2 |
Language | English |
Publishing date | 2021-04-26 |
Publishing country | United States |
Document type | Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't |
ZDB-ID | 1380686-5 |
ISSN | 1080-6059 ; 1080-6040 |
ISSN (online) | 1080-6059 |
ISSN | 1080-6040 |
DOI | 10.3201/eid2705.210015 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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