LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 13

Search options

  1. Article ; Online: Liver injury in the era of COVID-19.

    Cichoż-Lach, Halina / Michalak, Agata

    World journal of gastroenterology

    2021  Volume 27, Issue 5, Page(s) 377–390

    Abstract: ... in those with a severe or critical illness. COVID-19 might provoke a deterioration of liver function in patients ... prolongs the hospital stay. In general, patients who develop liver dysfunction in COVID-19 are mainly males ... focuses on a possible relationship between COVID-19 and the liver, potential molecular mechanisms ...

    Abstract Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has undoubtedly revolutionized the whole globe and given a new point of view on respiratory tract infections. Nevertheless, coronavirus disease 2019 (COVID-19) cannot be perceived as a disease limited only to pneumonia with diverse severity. More and more reports have demonstrated a wide range of possible systemic symptoms, including hepatic complications. Liver injury has been observed in a significant proportion of patients, especially in those with a severe or critical illness. COVID-19 might provoke a deterioration of liver function in patients with already diagnosed chronic liver diseases and without pre-existing liver disorders. The deterioration of liver function worsens the prognosis, increases the risk of a severe course of SARS-CoV-2 infection and prolongs the hospital stay. In general, patients who develop liver dysfunction in COVID-19 are mainly males, elderly people, and those with higher body mass index. The underlying mechanisms for hepatic failure in patients infected with SARS-CoV-2 are still unclear, nevertheless liver damage appears to be directly connected with virus-induced cytopathic effects. A liver injury observed during hospitalization might be simultaneously caused by the use of potentially hepatotoxic drugs, mainly antiviral agents. This minireview focuses on a possible relationship between COVID-19 and the liver, potential molecular mechanisms of liver damage, the characteristics of liver injury and suggested factors predisposing to hepatic manifestations in COVID-19 patients.
    MeSH term(s) Antiviral Agents/adverse effects ; COVID-19/complications ; COVID-19/pathology ; COVID-19/physiopathology ; Gastrointestinal Tract/physiopathology ; Host-Pathogen Interactions ; Humans ; Inflammation/complications ; Liver/pathology ; Liver Failure/chemically induced ; Liver Failure/virology ; Metabolic Syndrome/complications ; Prognosis ; SARS-CoV-2/physiology ; COVID-19 Drug Treatment
    Chemical Substances Antiviral Agents
    Language English
    Publishing date 2021-02-15
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2185929-2
    ISSN 2219-2840 ; 1007-9327
    ISSN (online) 2219-2840
    ISSN 1007-9327
    DOI 10.3748/wjg.v27.i5.377
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 6039: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article ; Online: Nintedanib-induced liver injury: Not every liver injury is virus or vaccine-induced in the era of COVID-19.

    Jena, Anuraag / Aggarwal, Tanushi / Mitra, Suvradeep / Singh, Anupam Kumar

    Liver international : official journal of the International Association for the Study of the Liver

    2022  Volume 42, Issue 5, Page(s) 1210–1211

    MeSH term(s) COVID-19 ; Chemical and Drug Induced Liver Injury, Chronic ; Humans ; Indoles ; Vaccines
    Chemical Substances Indoles ; Vaccines ; nintedanib (G6HRD2P839)
    Language English
    Publishing date 2022-02-28
    Publishing country United States
    Document type Letter
    ZDB-ID 2102783-3
    ISSN 1478-3231 ; 1478-3223
    ISSN (online) 1478-3231
    ISSN 1478-3223
    DOI 10.1111/liv.15206
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1632: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article ; Online: Liver and Biliary Tract Disease in Patients with Coronavirus disease-2019 Infection.

    Ekpanyapong, Sirina / Reddy, K Rajender

    Gastroenterology clinics of North America

    2022  Volume 52, Issue 1, Page(s) 13–36

    Abstract: ... liver disease during COVID-19 era are being regularly updated. Patients with chronic liver disease and cirrhosis ... Coronavirus disease-2019 (COVID-19) had become a global pandemic since March 2020 ... SARS-CoV-2 vaccination because it can reduce rate of COVID-19 infection, COVID-19-related ...

    Abstract Coronavirus disease-2019 (COVID-19) had become a global pandemic since March 2020. Although, the most common presentation is of pulmonary involvement, hepatic abnormalities can be encountered in up to 50% of infected individuals, which may be associated with disease severity, and the mechanism of liver injury is thought to be multifactorial. Guidelines for management in patients with chronic liver disease during COVID-19 era are being regularly updated. Patients with chronic liver disease and cirrhosis, including liver transplant candidates and liver transplant recipients are strongly recommended to receive SARS-CoV-2 vaccination because it can reduce rate of COVID-19 infection, COVID-19-related hospitalization, and mortality.
    MeSH term(s) Humans ; COVID-19 ; SARS-CoV-2 ; COVID-19 Vaccines ; Liver Diseases ; Biliary Tract Diseases
    Chemical Substances COVID-19 Vaccines
    Language English
    Publishing date 2022-10-04
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 92114-2
    ISSN 1558-1942 ; 0889-8553
    ISSN (online) 1558-1942
    ISSN 0889-8553
    DOI 10.1016/j.gtc.2022.09.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Se 123: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article: Living with liver disease in the era of COVID-19-the impact of the epidemic and the threat to high-risk populations.

    Barve, Pranav / Choday, Prithi / Nguyen, Anphong / Ly, Tri / Samreen, Isha / Jhooty, Sukhwinder / Umeh, Chukwuemeka A / Chaudhuri, Sumanta

    World journal of clinical cases

    2023  Volume 10, Issue 36, Page(s) 13167–13178

    Abstract: ... of the COVID-19 pandemic and the incidence of liver injury in COVID-19 patients, it is imperative ... of novel studies regarding COVID-19 induced liver injury, compiling data on the effects of the virus ... disease 2019 (COVID-19) infection have complaints of respiratory symptoms, other vital organs and systems ...

    Abstract The cardinal symptoms of severe acute respiratory syndrome coronavirus 2 infection as the pandemic began in 2020 were cough, fever, and dyspnea, thus characterizing the virus as a predominantly pulmonary disease. While it is apparent that many patients presenting acutely to the hospital with coronavirus disease 2019 (COVID-19) infection have complaints of respiratory symptoms, other vital organs and systems are also being affected. In fact, almost half of COVID-19 hospitalized patients were found to have evidence of some degree of liver injury. Incidence and severity of liver injury in patients with underlying liver disease were even greater. According to the Centers of Disease Control and Prevention, from August 1, 2020 to May 31, 2022 there have been a total of 4745738 COVID-19 hospital admissions. Considering the gravity of the COVID-19 pandemic and the incidence of liver injury in COVID-19 patients, it is imperative that we as clinicians understand the effects of the virus on the liver and conversely, the effect of underlying hepatobiliary conditions on the severity of the viral course itself. In this article, we review the spectrum of novel studies regarding COVID-19 induced liver injury, compiling data on the effects of the virus in various age and high-risk groups, especially those with preexisting liver disease, in order to obtain a comprehensive understanding of this disease process. We also provide an update of the impact of the new Omicron variant and the changing nature of COVID-19 pathogenesis.
    Language English
    Publishing date 2023-01-18
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 2307-8960
    ISSN 2307-8960
    DOI 10.12998/wjcc.v10.i36.13167
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  5. Article: The Impact of Alcohol Consumption and Addiction on Liver Transplantation Programs in the COVID-19 Era.

    Manikat, Richie / Ahmed, Aijaz / Kim, Donghee

    Hepatic medicine : evidence and research

    2023  Volume 15, Page(s) 141–149

    Abstract: ... recommended to optimize patient care in the post-COVID-19 era. Adequate planning and compassionate management ... The coronavirus disease 2019 (COVID-19) pandemic has caused significant shifts in alcohol ... at the societal level and bolstering mental health programs to mitigate healthcare workforce moral injury are ...

    Abstract The coronavirus disease 2019 (COVID-19) pandemic has caused significant shifts in alcohol consumption patterns in the United States, with potential long-term implications for liver transplantation (LT) programs. Alcohol consumption has increased, particularly in women, leading to a rise in alcohol-related liver disease (ALD) and alcohol use disorder. Psychological distress associated with the pandemic may further exacerbate alcohol addiction. ALD is now the most common indication for LT, with higher disease severity and complex clinical presentations, demanding a fundamental transformation in LT programs. Multidisciplinary cooperation among medical specialists, telemedicine, and remote healthcare are essential strategies to address these challenges. However, barriers to telemedicine and costs must be overcome. Curbing alcohol consumption at the societal level and bolstering mental health programs to mitigate healthcare workforce moral injury are recommended to optimize patient care in the post-COVID-19 era. Adequate planning and compassionate management of finite resources will be crucial for the successful continuation of LT programs amidst the concerning trends in alcohol consumption and addiction.
    Language English
    Publishing date 2023-09-29
    Publishing country New Zealand
    Document type Journal Article ; Review
    ZDB-ID 2520732-5
    ISSN 1179-1535
    ISSN 1179-1535
    DOI 10.2147/HMER.S384070
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article ; Online: Genetic insight into COVID-19-related liver injury.

    Bianco, Cristiana / Baselli, Guido / Malvestiti, Francesco / Santoro, Luigi / Pelusi, Serena / Manunta, Maria / Grasselli, Giacomo / Bandera, Alessandra / Scudeller, Luigia / Prati, Daniele / Valenti, Luca

    Liver international : official journal of the International Association for the Study of the Liver

    2020  Volume 41, Issue 1, Page(s) 227–229

    MeSH term(s) Alanine Transaminase ; COVID-19 ; Humans ; Liver ; Liver Diseases ; SARS-CoV-2
    Chemical Substances Alanine Transaminase (EC 2.6.1.2)
    Keywords covid19
    Language English
    Publishing date 2020-11-03
    Publishing country United States
    Document type Letter ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 2102783-3
    ISSN 1478-3231 ; 1478-3223
    ISSN (online) 1478-3231
    ISSN 1478-3223
    DOI 10.1111/liv.14708
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1632: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Article ; Online: Genetic insight into Covid-19 related liver injury

    C. Bianco / G. Baselli / F. Malvestiti / L. Santoro / S. Pelusi / M. Manunta / G. Grasselli / A. Bandera / L. Scudeller / D. Prati / L. Valenti

    2020  

    Abstract: ... of inflammation by facilitation of liver injury, which is a frequent feature of severe COVID-19 (3 ... risk of severe COVID-19 requiring hospitalization (1, 2). The mechanism may encompass promotion ... showed that a genetic FLD-risk score does not predispose to severe COVID-19 in UK Biobank population ...

    Abstract Metabolic dysfunction and fatty liver disease (FLD) are epidemiologically associated with increased risk of severe COVID-19 requiring hospitalization (1, 2). The mechanism may encompass promotion of inflammation by facilitation of liver injury, which is a frequent feature of severe COVID-19 (3). However, metabolic dysfunction rather than FLD itself may induce disease progression (2). Indeed, we previously showed that a genetic FLD-risk score does not predispose to severe COVID-19 in UK Biobank population-based cohort (UKBB) (4).
    Keywords Genetics ; Hepatitis ; Infectious disease ; Liver ; Settore MED/09 - Medicina Interna ; covid19
    Language English
    Publisher Wiley Blackwell Publishing
    Publishing country it
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  8. Article: Genetic insight into COVID-19-related liver injury

    Bianco, Cristiana / Baselli, Guido / Malvestiti, Francesco / Santoro, Luigi / Pelusi, Serena / Manunta, Maria / Grasselli, Giacomo / Bandera, Alessandra / Scudeller, Luigia / Prati, Daniele / Valenti, Luca

    Liver int

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #887396
    Database COVID19

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  9. Article ; Online: Genetic insight into Covid‐19 related liver injury

    Bianco, Cristiana / Baselli, Guido / Malvestiti, Francesco / Santoro, Luigi / Pelusi, Serena / Manunta, Maria / Grasselli, Giacomo / Bandera, Alessandra / Scudeller, Luigia / Prati, Daniele / Valenti, Luca

    Liver International ; ISSN 1478-3223 1478-3231

    2020  

    Keywords Hepatology ; covid19
    Language English
    Publisher Wiley
    Publishing country us
    Document type Article ; Online
    DOI 10.1111/liv.14708
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  10. Article ; Online: Alcohol-Related Liver Disease in the Covid-19 Era: Position Paper of the Italian Society on Alcohol (SIA).

    Testino, Gianni / Vignoli, Teo / Patussi, Valentino / Allosio, Pierluigi / Amendola, Maria Francesca / Aricò, Sarino / Baselice, Aniello / Balbinot, Patrizia / Campanile, Vito / Fanucchi, Tiziana / Greco, Giovanni / Macciò, Livia / Meneguzzi, Cristina / Mioni, Davide / Palmieri, Vincenzo Ostilio / Parisi, Michele / Renzetti, Doda / Rossin, Raffaella / Gandin, Claudia /
    Bottaro, Luigi Carlo / Bernardi, Mauro / Addolorato, Giovanni / Lungaro, Lisa / Zoli, Giorgio / Scafato, Emanuele / Caputo, Fabio

    Digestive diseases and sciences

    2021  Volume 67, Issue 6, Page(s) 1975–1986

    Abstract: ... regarding the management of ALD in patients with AUD in the era of COVID-19.: Methods: A panel of experts ... the SIA's criteria for the management of ALD in patients with COVID-19 as follows: (a) liver injury ... transplantation in the COVID-19 era.: Results and conclusions: The COVID-19 pandemic has rapidly carried us toward a new ...

    Abstract Background: Coronavirus Disease 2019 (COVID-19), firstly reported in China last November 2019, became a global pandemic. It has been shown that periods of isolation may induce a spike in alcohol use disorder (AUD). In addition, alcohol-related liver disease (ALD) is the most common consequence of excessive alcohol consumption worldwide. Moreover, liver impairment has also been reported as a common manifestation of COVID-19.
    Aims: The aim of our position paper was to consider some critical issues regarding the management of ALD in patients with AUD in the era of COVID-19.
    Methods: A panel of experts of the Italian Society of Alcohology (SIA) met via "conference calls" during the lockdown period to draft the SIA's criteria for the management of ALD in patients with COVID-19 as follows: (a) liver injury in patients with ALD and COVID-19 infection; (b) toxicity to the liver of the drugs currently tested to treat COVID-19 and the pharmacological interaction between medications used to treat AUD and to treat COVID-19; (c) reorganization of the management of compensated and decompensated ALD and liver transplantation in the COVID-19 era.
    Results and conclusions: The COVID-19 pandemic has rapidly carried us toward a new governance scenario of AUD and ALD which necessarily requires an in-depth review of the management of these diseases with a new safe approach (management of out-patients and in-patients following new rules of safety, telemedicine, telehealth, call meetings with clinicians, nurses, patients, and caregivers) without losing the therapeutic efficacy of multidisciplinary treatment.
    MeSH term(s) Alcoholism/complications ; Alcoholism/epidemiology ; Alcoholism/therapy ; COVID-19 ; Communicable Disease Control ; Humans ; Liver Diseases, Alcoholic/epidemiology ; Liver Diseases, Alcoholic/therapy ; Pandemics
    Language English
    Publishing date 2021-06-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 304250-9
    ISSN 1573-2568 ; 0163-2116
    ISSN (online) 1573-2568
    ISSN 0163-2116
    DOI 10.1007/s10620-021-07006-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Ui V Zs.35: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top