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Article: Heart transplant recipient survivor from COVID-19: The first case of Turkey.

Çınar, Güle / Sarıcaoğlu, Cahit / İnan, Bahadır / Dinçer, İrem / Çakıcı, Mehmet / Sayın, Tamer / Azap, Alpay / Akar, Ahmet Rüçhan

Turk gogus kalp damar cerrahisi dergisi

2020  Volume 28, Issue 4, Page(s) 674–679

Abstract: ... empirical. Herein, we report the first COVID-19 case of a heart transplant recipient in Turkey who presented ... recipients suffering from COVID-19. The lack of treatment protocols in the solid organ transplant recipients ... solid organ transplant recipients. The number of data about the spectrum of clinical illness ...

Abstract Any highly infectious and rapidly spreading disease is a primary concern for immunocompromised solid organ transplant recipients. The number of data about the spectrum of clinical illness, the treatment modalities, and the outcomes of COVID-19 in this vulnerable population is scant and still remains empirical. Herein, we report the first COVID-19 case of a heart transplant recipient in Turkey who presented with fever, postnasal discharge, and myalgias for two days. The possibility of lung involvement was ruled out by thoracic computed tomography. Despite stable vital signs, we reduced the intensity of immunosuppressive therapy and maintained home self-isolation promptly. We also commenced a five-day course of hydroxychloroquine 200 mg q12h initially. After confirmation of real-time reverse-transcriptase-polymerasechain- reaction testing of the nasopharyngeal swab positive for COVID-19, the patient was hospitalized. After a loading dose of favipiravir 1,600 mg b.i.d., the patient received a five-day course of favipiravir 600 mg q12h. He was discharged with cure after 23 days of hospital isolation and treatment. In conclusion, treatment process can be affected by the daily electrocardiography, hand-held portable echocardiography, myocardial injury markers, and pulse oximeter for selfmonitoring in the follow-up of previous heart transplant recipients suffering from COVID-19. The lack of treatment protocols in the solid organ transplant recipients with COVID-19 infection and the controversies about the protective effect of immunosuppression invite a global and update discussion.
Language English
Publishing date 2020-10-21
Publishing country Turkey
Document type Case Reports
ISSN 1301-5680
ISSN 1301-5680
DOI 10.5606/tgkdc.dergisi.2020.20291
Database MEDical Literature Analysis and Retrieval System OnLINE

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