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  1. Article ; Online: Prone positioning improves oxygenation and lung recruitment in patients with SARS-CoV-2 acute respiratory distress syndrome; a single centre cohort study of 20 consecutive patients.

    Clarke, Jennifer / Geoghegan, Pierce / McEvoy, Natalie / Boylan, Maria / Ní Choileáin, Orna / Mulligan, Martin / Hogan, Grace / Keogh, Aoife / McElvaney, Oliver J / McElvaney, Oisín F / Bourke, John / McNicholas, Bairbre / Laffey, John G / McElvaney, Noel G / Curley, Gerard F

    BMC research notes

    2021  Volume 14, Issue 1, Page(s) 20

    Abstract: ... oxygenation in invasively ventilated patients with SARS-CoV-2 ARDS.: Results: This was a prospective ... cohort study in the Intensive Care Unit (ICU) of a tertiary referral centre. We included 20 consecutive ... invasively ventilated patients with laboratory confirmed SARS-CoV-2 related ARDS who underwent ...

    Abstract Objective: We aimed to characterize the effects of prone positioning on respiratory mechanics and oxygenation in invasively ventilated patients with SARS-CoV-2 ARDS.
    Results: This was a prospective cohort study in the Intensive Care Unit (ICU) of a tertiary referral centre. We included 20 consecutive, invasively ventilated patients with laboratory confirmed SARS-CoV-2 related ARDS who underwent prone positioning in ICU as part of their management. The main outcome was the effect of prone positioning on gas exchange and respiratory mechanics. There was a median improvement in the PaO
    MeSH term(s) COVID-19/metabolism ; COVID-19/therapy ; Cohort Studies ; Humans ; Lung/metabolism ; Male ; Middle Aged ; Oxygen/metabolism ; Prone Position ; Prospective Studies ; Respiration, Artificial
    Chemical Substances Oxygen (S88TT14065)
    Language English
    Publishing date 2021-01-09
    Publishing country England
    Document type Clinical Trial ; Journal Article
    ZDB-ID 2413336-X
    ISSN 1756-0500 ; 1756-0500
    ISSN (online) 1756-0500
    ISSN 1756-0500
    DOI 10.1186/s13104-020-05426-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Prone positioning improves oxygenation and lung recruitment in patients with SARS-CoV-2 acute respiratory distress syndrome; a single centre cohort study of 20 consecutive patients

    Jennifer Clarke / Pierce Geoghegan / Natalie McEvoy / Maria Boylan / Orna Ní Choileáin / Martin Mulligan / Grace Hogan / Aoife Keogh / Oliver J. McElvaney / Oisín F. McElvaney / John Bourke / Bairbre McNicholas / John G. Laffey / Noel G. McElvaney / Gerard F. Curley

    BMC Research Notes, Vol 14, Iss 1, Pp 1-

    2021  Volume 6

    Abstract: ... were partly due to lung recruitment. Prone positioning should be considered in patients with SARS-CoV-2 ... on respiratory mechanics and oxygenation in invasively ventilated patients with SARS-CoV-2 ARDS. Results This was ... with prone positioning. Prone positioning was effective in improving oxygenation in SARS-CoV-2 ARDS. Furthermore, poor ...

    Abstract Abstract Objective We aimed to characterize the effects of prone positioning on respiratory mechanics and oxygenation in invasively ventilated patients with SARS-CoV-2 ARDS. Results This was a prospective cohort study in the Intensive Care Unit (ICU) of a tertiary referral centre. We included 20 consecutive, invasively ventilated patients with laboratory confirmed SARS-CoV-2 related ARDS who underwent prone positioning in ICU as part of their management. The main outcome was the effect of prone positioning on gas exchange and respiratory mechanics. There was a median improvement in the PaO2/FiO2 ratio of 132 in the prone position compared to the supine position (IQR 67–228). We observed lower PaO2/FiO2 ratios in those with low (< median) baseline respiratory system static compliance, compared to those with higher (> median) static compliance (P < 0.05). There was no significant difference in respiratory system static compliance with prone positioning. Prone positioning was effective in improving oxygenation in SARS-CoV-2 ARDS. Furthermore, poor respiratory system static compliance was common and was associated with disease severity. Improvements in oxygenation were partly due to lung recruitment. Prone positioning should be considered in patients with SARS-CoV-2 ARDS.
    Keywords Respiratory distress syndrome ; Adult ; Prone position ; Severe acute respiratory syndrome coronavirus 2 ; Medicine ; R ; Biology (General) ; QH301-705.5 ; Science (General) ; Q1-390
    Subject code 610
    Language English
    Publishing date 2021-01-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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