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  1. Article: Multifocal atrial tachycardia responsive to parenteral magnesium.

    Cohen, L / Kitzes, R / Shnaider, H

    Magnesium research

    1988  Volume 1, Issue 3-4, Page(s) 239–242

    Abstract: Two groups of patients with multifocal atrial tachycardia (MAT) were treated with the intramuscular ... a higher and more sustained serum magnesium concentration, converted the arrhythmia to normal sinus rhythm ... in a shorter period of time (1-2 hours) than the intravenous regimen (4-8 hours). Magnesium-sparing diuretics ...

    Abstract Two groups of patients with multifocal atrial tachycardia (MAT) were treated with the intramuscular and continuous intravenous magnesium sulphate regimens used in pre-eclampsia. Both routes of administration were successful in causing reversion to sinus rhythm but the intramuscular regimen, by attaining a higher and more sustained serum magnesium concentration, converted the arrhythmia to normal sinus rhythm in a shorter period of time (1-2 hours) than the intravenous regimen (4-8 hours). Magnesium-sparing diuretics should be used in the treatment of patients with chronic obstructive pulmonary disease and congestive heart failure, which are both conditions associated with magnesium deficiency and MAT.
    MeSH term(s) Aged ; Humans ; Infusions, Intravenous ; Injections, Intramuscular ; Kinetics ; Magnesium/blood ; Magnesium Sulfate/administration & dosage ; Magnesium Sulfate/therapeutic use ; Male ; Middle Aged ; Tachycardia/drug therapy ; Tachycardia/physiopathology
    Chemical Substances Magnesium Sulfate (7487-88-9) ; Magnesium (I38ZP9992A)
    Language English
    Publishing date 1988-12
    Publishing country England
    Document type Comparative Study ; Journal Article
    ZDB-ID 1036384-1
    ISSN 0953-1424
    ISSN 0953-1424
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  2. Article: Magnesium and potassium therapy in multifocal atrial tachycardia.

    Iseri, L T / Fairshter, R D / Hardemann, J L / Brodsky, M A

    American heart journal

    1985  Volume 110, Issue 4, Page(s) 789–794

    Abstract: Eight patients with multifocal atrial tachycardia received 7 to 12 gm of magnesium ... There were seven patients who retained more than 20 mEq of the infused magnesium. Multifocal atrial ... tachycardia respond favorably to parenteral magnesium and potassium. We believe that serum magnesium ...

    Abstract Eight patients with multifocal atrial tachycardia received 7 to 12 gm of magnesium sulfate intravenously over a 5-hour period. Potassium supplements were given initially or added later. Initial arterial blood gases showed mean pH 7.48 +/- 0.03, PcO2 39.7 torr, PO2 72 torr, HCO-3 29.8 +/- 4.5 mEq/L, and base excess 6.84 +/- 3.78 mEq/L. Initial serum magnesium correlated well with initial serum potassium. Three patients had subnormal levels of magnesium and potassium. The level of serum magnesium rose with an intravenous injection magnesium and serum potassium levels tended to fall unless they were supplanted with potassium. There were seven patients who retained more than 20 mEq of the infused magnesium. Multifocal atrial tachycardia was successfully converted to sinus rhythm or sinus tachycardia in seven patients. Multifocal atrial rhythm (at slow rate) persisted in one patient. Two patients with falling serum potassium levels required potassium supplements. Results of this study confirm that patients with multifocal atrial tachycardia respond favorably to parenteral magnesium and potassium. We believe that serum magnesium administered together with serum potassium stabilizes the ionic balance of atrial cells and thus prevents spontaneous ectopy.
    MeSH term(s) Aged ; Atrioventricular Node/physiopathology ; Electrocardiography ; Female ; Heart Atria/physiopathology ; Humans ; Infusions, Parenteral ; Magnesium/blood ; Magnesium Sulfate/therapeutic use ; Male ; Middle Aged ; Potassium/blood ; Potassium/therapeutic use ; Tachycardia/drug therapy ; Tachycardia/physiopathology
    Chemical Substances Magnesium Sulfate (7487-88-9) ; Magnesium (I38ZP9992A) ; Potassium (RWP5GA015D)
    Language English
    Publishing date 1985-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80026-0
    ISSN 1097-6744 ; 0002-8703
    ISSN (online) 1097-6744
    ISSN 0002-8703
    DOI 10.1016/0002-8703(85)90458-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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