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  1. Article ; Online: Pneumomediastinum in critically ill adult with COVID-19.

    Collercandy, N / Guillon, A

    Medicina intensiva

    2022  Volume 46, Issue 11, Page(s) 663

    MeSH term(s) Humans ; COVID-19/complications ; Mediastinal Emphysema/diagnostic imaging ; Mediastinal Emphysema/etiology ; Critical Illness ; SARS-CoV-2 ; Risk Factors
    Language English
    Publishing date 2022-09-12
    Publishing country Spain
    Document type Journal Article
    ISSN 2173-5727
    ISSN (online) 2173-5727
    DOI 10.1016/j.medine.2020.06.016
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Pneumomediastinum in critically ill adult with COVID-19.

    Collercandy, N / Guillon, A

    Medicina intensiva

    2020  

    Keywords covid19
    Language Spanish
    Publishing date 2020-07-04
    Publishing country Spain
    Document type Journal Article
    ISSN 2173-5727
    ISSN (online) 2173-5727
    DOI 10.1016/j.medin.2020.06.010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Pneumomediastinum in critically ill adult with COVID-19

    Collercandy, N. / Guillon, A.

    Medicina Intensiva ; ISSN 0210-5691

    2020  

    Keywords Critical Care and Intensive Care Medicine ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    DOI 10.1016/j.medin.2020.06.010
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Risk factors of pneumothorax and pneumomediastinum in COVID-19: a matched case-control study.

    Lee, Se Ju / Kim, Jinnam / Lee, Ki Hyun / Lee, Jung Ah / Kim, Chang Hyup / Lee, Su Hwan / Park, Byung Jo / Kim, Jung Ho / Ahn, Jin Young / Jeong, Su Jin / Ku, Nam Su / Yeom, Joon-Sup / Choi, Jun Yong

    BMC infectious diseases

    2023  Volume 23, Issue 1, Page(s) 137

    Abstract: ... enrolled adult patients with COVID-19, admitted to a critical care unit from March 1, 2020, to January 31 ... of pneumothorax (PNX)/pneumomediastinum (PNM) associated with COVID-19 have been reported, and the incidence is ... higher in critically ill patients. Despite using a protective ventilation strategy, PNX/PNM still occurs ...

    Abstract Background: During the novel coronavirus disease-2019 pandemic, a considerable number of pneumothorax (PNX)/pneumomediastinum (PNM) associated with COVID-19 have been reported, and the incidence is higher in critically ill patients. Despite using a protective ventilation strategy, PNX/PNM still occurs in patients on invasive mechanical ventilation (IMV). This matched case-control study aims to identify the risk factors and clinical characteristics of PNX/PNM in COVID-19.
    Methods: This retrospective study enrolled adult patients with COVID-19, admitted to a critical care unit from March 1, 2020, to January 31, 2022. COVID-19 patients with PNX/PNM were compared, in a 1-2 ratio, to COVID-19 patients without PNX/PNM, matched for age, gender, and worst National Institute of Allergy and Infectious Diseases ordinal scale. Conditional logistic regression analysis was performed to assess the risk factors for PNX/PNM in COVID-19.
    Results: 427 patients with COVID-19 were admitted during the period, and 24 patients were diagnosed with PNX/PNM. Body mass index (BMI) was significantly lower in the case group (22.8 kg/m
    Conclusions: Higher BMI tended to show a protective effect against PNX/PNM due to COVID-19 and delayed application of IMV might be a contributive factor for this complication.
    MeSH term(s) Adult ; Humans ; Case-Control Studies ; Pneumothorax/epidemiology ; Pneumothorax/etiology ; Retrospective Studies ; Mediastinal Emphysema/epidemiology ; Mediastinal Emphysema/etiology ; COVID-19/complications
    Language English
    Publishing date 2023-03-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 2041550-3
    ISSN 1471-2334 ; 1471-2334
    ISSN (online) 1471-2334
    ISSN 1471-2334
    DOI 10.1186/s12879-023-08104-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Surgical treatment of tension pneumomediastinum in patients with covid-19 at the field hospital: a case series.

    Thuan, Phan Quang / Phuong, Pham Phan Phuong / Anh, Huynh Phuong Nguyet / Long, Le Phi / Khoi, Le Minh

    Journal of cardiothoracic surgery

    2022  Volume 17, Issue 1, Page(s) 202

    Abstract: ... threatening complication in critically ill COVID-19 patients requiring mechanical ventilation. Surgical ... Background: Tension pneumomediastinum is one of the most serious complications in COVID-19 ... promptly.: Case presentation: We reported 7 COVID-19 patients with tension pneumomediastinum ...

    Abstract Background: Tension pneumomediastinum is one of the most serious complications in COVID-19 patients with respiratory distress requiring invasive mechanical ventilation. This complication can lead to rapid hemodynamic instability and death if it is not recognized in a timely manner and intervenes promptly.
    Case presentation: We reported 7 COVID-19 patients with tension pneumomediastinum at a field hospital. All patients were critically ill with ARDS. These 7 patients, including 3 females and 4 males in this series, were aged between 39 and 70 years. Tension pneumomediastinum occurred on the first day of mechanical ventilation in 3 patients and later in the course of hospital stay, even 10 days after being intubated and ventilated. The tension pneumomediastinum caused hemodynamic instability and worsened respiratory mechanics with imminent cardiopulmonary collapse. In this series, we used two surgical techniques: (i) mediastinal decompression by suprasternal drainage with or without simultaneous pleural drainage in the first two cases and (ii) mediastinal drainage via suprasternal and subxiphoid incisions in 5 patients. The surgical procedures were feasible and reversed the pending cardiopulmonary collapse. Four patients had a favorable postprocedural period and were discharged from the intensive care center. Both patients undergoing suprasternal drainage died of failed/recurrent tension pneumomediastinum and nosocomial infection. Only one in five patients who underwent mediastinal drainage via suprasternal and subxiphoid incisions died of septic shock secondary to ventilator-associated pneumonia.
    Conclusion: Tension pneumomediastinum was a life-threatening complication in critically ill COVID-19 patients requiring mechanical ventilation. Surgical mediastinal decompression was the salvage procedure. The surgical technique of mediastinal drainage via suprasternal and subxiphoid incisions proved an advantage in tension relief, hemodynamic improvement and mortality reduction.
    MeSH term(s) Adult ; Aged ; COVID-19/complications ; Critical Illness ; Female ; Humans ; Male ; Mediastinal Emphysema/etiology ; Mediastinal Emphysema/surgery ; Middle Aged ; Mobile Health Units ; Respiration, Artificial/adverse effects
    Language English
    Publishing date 2022-08-24
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 2227224-0
    ISSN 1749-8090 ; 1749-8090
    ISSN (online) 1749-8090
    ISSN 1749-8090
    DOI 10.1186/s13019-022-01966-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Subcutaneous emphysema and pneumomediastinum in patients with COVID-19 disease; case series from a tertiary care hospital in Pakistan.

    Sethi, S M / Ahmed, A S / Hanif, S / Aqeel, M / Zubairi, A B S

    Epidemiology and infection

    2021  Volume 149, Page(s) e37

    Abstract: ... in critically ill COVID-19 ARDS patients. ... Since December 2019, the clinical symptoms of coronavirus disease 2019 (COVID-19) and ... increasing, so is the incidence of subcutaneous emphysema (SE). We report 10 patients of COVID-19, with SE ...

    Abstract Since December 2019, the clinical symptoms of coronavirus disease 2019 (COVID-19) and its complications are evolving. As the number of COVID patients requiring positive pressure ventilation is increasing, so is the incidence of subcutaneous emphysema (SE). We report 10 patients of COVID-19, with SE and pneumomediastinum. The mean age of the patients was 59 ± 8 years (range, 23-75). Majority of them were men (80%), and common symptoms were dyspnoea (100%), fever (80%) and cough (80%). None of them had any underlying lung disorder. All patients had acute respiratory distress syndrome on admission, with a median PaO2/FiO2 ratio of 122.5. Eight out of ten patients had spontaneous pneumomediastinum on their initial chest x-ray in the emergency department. The median duration of assisted ventilation before the development of SE was 5.5 days (interquartile range, 5-10 days). The highest positive end-expiratory pressure (PEEP) was 10 cmH2O for patients recieving invasive mechanical ventilation, while 8 cmH2O was the average PEEP in patients who had developed subcutaneous emphysema on non-invasive ventilation. All patients received corticosteroids while six also received tocilizumab, and seven received convalescent plasma therapy, respectively. Seven patients died during their hospital stay. All patients either survivor or non-survivor had prolonged hospital stay with an average of 14 days (range 8-25 days). Our findings suggest that it is lung damage secondary to inflammatory response due to COVID-19 triggered by the use of positive pressure ventilation which resulted in this complication. We conclude that the development of spontaneous pneumomediastinum and SE whenever present, is associated with poor outcome in critically ill COVID-19 ARDS patients.
    MeSH term(s) Adult ; Aged ; COVID-19/complications ; COVID-19/epidemiology ; Female ; Humans ; Male ; Mediastinal Emphysema/epidemiology ; Mediastinal Emphysema/etiology ; Middle Aged ; Pakistan/epidemiology ; SARS-CoV-2 ; Subcutaneous Emphysema/epidemiology ; Subcutaneous Emphysema/etiology ; Tertiary Care Centers ; Young Adult
    Language English
    Publishing date 2021-01-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 632982-2
    ISSN 1469-4409 ; 0950-2688
    ISSN (online) 1469-4409
    ISSN 0950-2688
    DOI 10.1017/S095026882100011X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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