Article: Case Report: Management of Malignancy-Exacerbated Pemphigus Vulgaris During COVID-19 Pandemic.
2021 Volume 8, Page(s) 708284
Abstract: ... of pemphigus. Moreover, the infective risks had to be minimized during the peak of the COVID-19 pandemic ... exacerbated pemphigus vulgaris which required a careful diagnostic process in order to rule out paraneoplastic ... Pemphigus vulgaris is an intraepidermal autoimmune mucocutaneous blistering disease ...
| Abstract | Pemphigus vulgaris is an intraepidermal autoimmune mucocutaneous blistering disease whose etiopathogenesis includes various trigger factors, i.e., drugs and malignancies. We present a case of malignancy-exacerbated pemphigus vulgaris which required a careful diagnostic process in order to rule out paraneoplastic pemphigus, along with the challenges posed by the need of treating both cutaneous and oncologic diseases. Possible post-operative complications post-poned the start of first-line immunosuppressive treatment of pemphigus. Moreover, the infective risks had to be minimized during the peak of the COVID-19 pandemic in Italy. Intravenous immunoglobulins were chosen as "bridge" therapy before the tumor surgical excision, followed by rituximab in post-operative phase. |
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| Language | English |
| Publishing date | 2021-08-11 |
| Publishing country | Switzerland |
| Document type | Case Reports |
| ZDB-ID | 2775999-4 |
| ISSN | 2296-858X |
| ISSN | 2296-858X |
| DOI | 10.3389/fmed.2021.708284 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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