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  1. Article ; Online: SARS-CoV-2 infection affects the lower urinary tract and male genital system: A systematic review.

    Creta, Massimiliano / Sagnelli, Caterina / Celentano, Giuseppe / Napolitano, Luigi / La Rocca, Roberto / Capece, Marco / Califano, Gianluigi / Calogero, Armando / Sica, Antonello / Mangiapia, Francesco / Ciccozzi, Massimo / Fusco, Ferdinando / Mirone, Vincenzo / Sagnelli, Evangelista / Longo, Nicola

    Journal of medical virology

    2021  Volume 93, Issue 5, Page(s) 3133–3142

    Abstract: ... of the involvement of the lower urinary tract and male genital system in COVID-19. ... to December 2020 on the involvement of urinary and male genital systems in COVID-19. Sixteen studies involving ... lower urinary tract symptoms (LUTS) were observed in 43 patients and deterioration of pre-existing LUTS in 7. Bladder ...

    Abstract PubMed, Scopus, and ISI Web of Knowledge databases were searched to identify studies published up to December 2020 on the involvement of urinary and male genital systems in COVID-19. Sixteen studies involving a total of 575 patients (538 males and 37 females) were included in this systematic review. The COVID-19 phase was available for 479 patients: 426 in the acute and 53 in the recovery phase. De novo lower urinary tract symptoms (LUTS) were observed in 43 patients and deterioration of pre-existing LUTS in 7. Bladder hemorrhage was observed in three patients and acute urinary retention in one. Regarding the male genital system, scrotal discomfort was observed in 8 patients, swelling in 14, pain in 16, and erythema in 1; low flow priapism was observed in 2 patients. Ultrasound examination identified acute orchitis in 10 patients, acute epididymitis in 7, and acute epididymo-orchitis in 16. A case-control study reported that patients with moderate COVID-19 show a significant reduction in sperm concertation, the total number of sperms per ejaculate, progressive motility, and complete motility. In contrast to what is known from the first studies on the subject, this review also includes subsequent studies that give evidence of the involvement of the lower urinary tract and male genital system in COVID-19.
    MeSH term(s) COVID-19/pathology ; Genitalia, Male/pathology ; Humans ; Male ; SARS-CoV-2 ; Urinary Tract/pathology
    Language English
    Publishing date 2021-03-01
    Publishing country United States
    Document type Journal Article ; Systematic Review
    ZDB-ID 752392-0
    ISSN 1096-9071 ; 0146-6615
    ISSN (online) 1096-9071
    ISSN 0146-6615
    DOI 10.1002/jmv.26883
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1320: Show issues Location:
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  2. Article ; Online: Does SARS-CoV-2 Affect Male Urogenital System?

    Balawender, Krzysztof / Pliszka, Anna / Krowiak, Anita / Sito, Maksymilian / Grabarek, Beniamin Oskar / Boroń, Dariusz

    Current pharmaceutical biotechnology

    2022  Volume 23, Issue 15, Page(s) 1792–1799

    Abstract: ... urogenital system", "male infertility", "lower urinary tract symptoms". Therefore, there was no explicit and ... the following inclusion criteria: human studies, focus on Sars-CoV-2 and male urogenital system or ... and 8 systematic reviews were accepted. In our review paper, we presented data from 2 systematic ...

    Abstract Background: Widely known facts about Sars-Cov-2 infection's impact on urogenital system may play a relevant role in under-standing, diagnosing, and preventing male urological disorders. Sars-CoV-2 attacks the vascular endothelium of the entire organism; therefore, infection complications are visible in various organs. Relatively small number of original studies are available on Sars-CoV-2 infection and the effect on the reproductive system and fertility in men. The vast majority of publications focus only on discussing the effects of COVID-19 infection on just one aspect of male urology or fertility.
    Objectives: The aim of this review was to present the current understanding of the effects of COVID-19 infection on the male genitourinary system in the context of nephrological and reproductive system complications in men, considering the potential pathomechanisms causing significant nephrological disorders in the course of viral infection, as well as long-term effects of Sars-CoV-2 infection. We tried to make clinicians aware of urogenital complications in the course of COVID-19 occurrence and encourage them to create preventive procedures.
    Methods: The article presented has been classified by us as "review". Of course, when searching for publications and making their critique, we focused primarily on the words: "Sars-CoV-2", "male urogenital system", "male infertility", "lower urinary tract symptoms". Therefore, there was no explicit and rigorous work selection methodology. Search strategies were based on the experience of the authors of the work. In order to select articles for the systematic review, literature searches were conducted on PubMed (https://pubmed.ncbi.nlm.nih.gov) using the following keywords: "Sars-CoV- 2" AND "male urogenital system" OR "male infertility" The search results were retrieved and manually screened for duplicate removal. Then abstracts and titles were checked for relevance. The articles were selected if they met the following inclusion criteria: human studies, focus on Sars-CoV-2 and male urogenital system or male infertility, published from 2020 to 2021, written in English, free full-text available. We included clinical trials, meta-analyses, randomized controlled studies, reviews, systematic reviews.
    Results: After the literature search, a total of 267 articles were retrieved, including 153 reviews, 53 systematic reviews, and 61 original articles. Eventually, after abstract and title screening, 2 original articles, 29 reviews, and 8 systematic reviews were accepted. In our review paper, we presented data from 2 systematic reviews, 17 reviews, 2 meta-analyses, 1 case study, and 18 original articles, including 3 animals studies, 2 in vitro studies, and 14 human studies.
    Conclusion: Serious concerns for urologists among COVID-19 patients should be mainly orchitis, male infertility, priapism, erectile dysfunction, and lower urinary tract symptoms. It seems that the conclusions drawn should be treated with caution because, as mentioned above, in a pandemic, urinary complications are underdiagnosed and there are too few clinical trials and case reports.
    MeSH term(s) Humans ; Male ; SARS-CoV-2 ; COVID-19 ; Pandemics ; Urinary Tract ; Infertility
    Language English
    Publishing date 2022-03-07
    Publishing country Netherlands
    Document type Review ; Journal Article
    ZDB-ID 2132197-8
    ISSN 1873-4316 ; 1389-2010
    ISSN (online) 1873-4316
    ISSN 1389-2010
    DOI 10.2174/1389201023666220307102147
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6212: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

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