Article: Severe acute respiratory syndrome coronavirus 2 indirectly damages kidney structures.
2020 Volume 13, Issue 6, Page(s) 1101–1104
Abstract: Background: The objectives were to characterize Severe acute respiratory syndrome coronavirus 2 ... SARS-CoV-2) disease 2019 (COVID-19) in patients with acute kidney injury (AKI).: Methods: Kidney ... to angiotensin-converting enzyme 2 and transmembrane protease serine 2 kidney staining.: Conclusions ...
| Abstract | Background: The objectives were to characterize Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) disease 2019 (COVID-19) in patients with acute kidney injury (AKI). Methods: Kidney biopsy samples in two Caucasian patients and one African with COVID-19 AKI were investigated. Results: All patients had a high-level non-selective glomerular proteinuria. SARS-CoV-2 samples by real-time polymerase chain reaction (RT- PCR) assay were all-negative, as well as for virus particles in the kidney by electron microscopy. The three patients and patients with other AKI did not differ significantly with regard to angiotensin-converting enzyme 2 and transmembrane protease serine 2 kidney staining. Conclusions: The kidney damage particularly in Caucasians in COVID-19 seems to be an AKI, possibly by the systemic inflammatory response. |
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| Language | English | |||||
| Publishing date | 2020-12-14 | |||||
| Publishing country | England | |||||
| Document type | Journal Article | |||||
| ZDB-ID | 2655800-2 | |||||
| ISSN | 2048-8513 ; 2048-8505 | |||||
| ISSN (online) | 2048-8513 | |||||
| ISSN | 2048-8505 | |||||
| DOI | 10.1093/ckj/sfaa209 | |||||
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| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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